Journal of Yeungnam Medical Science

Yeungnam University College of Medicine, Yeungnam University Institute Medical Science (영남대 의대 학술지 편집위원회)
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Rheumatoid arthritis accompanied by Gitelman syndrome

류마티스관절염 환자에 동반된 Gitelman 증후군

  • Park, Min Gi (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center) ;
  • Lee, Ji Hyun (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center) ;
  • Kim, Sung Jun (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center) ;
  • Park, Su Ho (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center) ;
  • Park, Suk Ki (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center) ;
  • Choi, Joon Sul (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center) ;
  • Hwang, Ji Yeon (Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center)
  • 박민기 (메리놀병원 류마티스 내과) ;
  • 이지현 (메리놀병원 류마티스 내과) ;
  • 김성준 (메리놀병원 류마티스 내과) ;
  • 박수호 (메리놀병원 류마티스 내과) ;
  • 박석기 (메리놀병원 류마티스 내과) ;
  • 최준설 (메리놀병원 류마티스 내과) ;
  • 황지연 (메리놀병원 류마티스 내과)
  • Received : 2016.03.04
  • Accepted : 2016.06.02
  • Published : 2017.06.30
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Abstract

Gitelman syndrome is a condition caused by a mutation of the thiazide sensitive Na-Cl cotransporter gene on the distal convoluted tubule. It results in a variety of clinical features, including hypokalemia, hypomagnesemia, hypocalciuria, and metabolic alkalosis. It is often diagnosed in asymptomatic adults presented with unexplained hypokalemia; however, it is sometimes associated with muscular cramps, numbness, fatigue, weakness, or paralysis. We experienced a case of rheumatoid arthritis accompanied by Gitelman syndrome, presented with hand tremor. We diagnosed her using renal clearance study and genetic analysis. Here, we report our experiences regarding this case along with a literature review.

Keywords

References

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