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Asymptomatic Pulmonary Tuberculosis in Infant

유아의 무증상 폐결핵

  • Hwang, Ji Hyen (Department of Pediatrics, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Je, Bo-Kyung (Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine) ;
  • Kim, Yun-Kyung (Department of Pediatrics, Korea University Ansan Hospital, Korea University College of Medicine)
  • 황지현 (고려대학교 의과대학 고려대학교 안산병원 소아청소년과) ;
  • 제보경 (고려대학교 의과대학 고려대학교 안산병원 영상의학과) ;
  • 김윤경 (고려대학교 의과대학 고려대학교 안산병원 소아청소년과)
  • Received : 2016.09.13
  • Accepted : 2016.09.21
  • Published : 2017.08.25

Abstract

A 3-month-old asymptomatic infant presented with bilateral extensive consolidation of the lungs, which was diagnosed as pulmonary tuberculosis. Evaluation of the baby for tuberculosis was initiated because of a history of contact with a known tuberculosis patient. This case is interesting because the baby rarely showed symptoms during the whole course of the disease.

영아에서의 결핵은 소아나 성인의 결핵에 비해 더 심한 증상과 합병증을 초래할 수 있다. 하지만 증상이 전형적이지 않거나 균 검출이 잘 되지 않는 경우가 많아 진단에 어려움이 있다. 본 증례는 폐결핵으로 진단된 3개월 환아에 대한 보고이다. 환아는 광범위한 양측 폐의 병변에도 불구하고 발열이나 호흡곤란, 기침 등의 증상을 보이지 않았으며 항결핵제 투약 6개월째 폐병변이 호전되었다. 일부 영아 결핵에서 증상이 나타나지 않는 것은 면역반응의 미성숙으로 부분적으로 설명될 수 있을 것이다. 따라서 영아에서 결핵 접촉자 검진의 중요성이 강조된다.

Keywords

References

  1. Amodio J, Abramson S, Berdon W. Primary pulmonary tuberculosis in infancy: a resurgent disease in the urban United States. Pediatr Radiol 1986;16:185-9. https://doi.org/10.1007/BF02456283
  2. Schaaf HS, Gie RP, Beyers N, Smuts N, Donald PR. Tuberculosis in infants less than 3 months of age. Arch Dis Child 1993;69:371-4. https://doi.org/10.1136/adc.69.3.371
  3. Vallejo JG, Ong LT, Starke JR. Clinical features, diagnosis, and treatment of tuberculosis in infants. Pediatrics 1994;94:1-7.
  4. Snider DE Jr, Bloch AB. Congenital tuberculosis. Tubercle 1984;65:81-2. https://doi.org/10.1016/0041-3879(84)90057-6
  5. Hageman J, Shulman S, Schreiber M, Luck S, Yogev R. Congenital tuberculosis: critical reappraisal of clinical findings and diagnostic procedures. Pediatrics 1980;66:980-4.
  6. Myers JP, Perlstein PH, Light IJ, Towbin RB, Dincsoy HP, Dincsoy MY. Tuberculosis in pregnancy with fatal congenital infection. Pediatrics 1981;67:89-94.
  7. Nemir RL, O'Hare D. Congenital tuberculosis. Review and diagnostic guidelines. Am J Dis Child 1985;139:284-7. https://doi.org/10.1001/archpedi.1985.02140050078028
  8. Newton SM, Brent AJ, Anderson S, Whittaker E, Kampmann B. Paediatric tuberculosis. Lancet Infect Dis 2008;8:498-510. https://doi.org/10.1016/S1473-3099(08)70182-8
  9. Madhi SA, Huebner RE, Doedens L, Aduc T, Wesley D, Cooper PA. HIV-1 co-infection in children hospitalised with tuberculosis in South Africa. Int J Tuberc Lung Dis 2000;4:448-54.
  10. Hussey G, Chisholm T, Kibel M. Miliary tuberculosis in children: a review of 94 cases. Pediatr Infect Dis J 1991;10:832-6. https://doi.org/10.1097/00006454-199111000-00008
  11. Kim WS, Choi JI, Cheon JE, Kim IO, Yeon KM, Lee HJ. Pulmonary tuberculosis in infants: radiographic and CT findings. AJR Am J Roentgenol 2006;187:1024-33. https://doi.org/10.2214/AJR.04.0751