Acupuncture for Prehypertension and Stage 1 Hypertension in Postmenopausal Women: A Randomized Controlled Pilot Trial

폐경 후 고혈압 전단계 및 1기 고혈압에 대한 침 치료 효과: 무작위 대조 예비연구

  • Kim, Jung-Eun (Clinical Research Division, Korea Institute of Oriental Medicine) ;
  • Choi, Sun-Mi (KM standards center, Korea Institute of Oriental Medicine) ;
  • Choi, Jin-Bong (College of Korean Medicine, Dongshin University) ;
  • Kim, Hyeong-Jun (College of Korean Medicine, Semyung University) ;
  • Kwon, Ojin (Clinical Research Division, Korea Institute of Oriental Medicine) ;
  • Kim, Jae-Hong (College of Korean Medicine, Dongshin University) ;
  • Park, Ji-Eun (Mibyeong Research Center, Korea Institute of Oriental Medicine)
  • 김정은 (한국한의학연구원 임상연구부) ;
  • 최선미 (한국한의학연구부 한의기술표준센터) ;
  • 최진봉 (동신대학교 한의과대학) ;
  • 김형준 (세명대학교 한의과대학) ;
  • 권오진 (한국한의학연구원 임상연구부) ;
  • 김재홍 (동신대학교 한의과대학) ;
  • 박지은 (한국한의학연구원 미병연구단)
  • Received : 2017.08.29
  • Accepted : 2017.09.09
  • Published : 2017.09.27


Objectives : The aim of this study was to assess the effectiveness of acupuncture in treating prehypertension and stage 1 hypertension in postmenopausal women. Methods : The study was a multi-center, four-arm, non-blinded, randomized clinical trial. Sixty participants were randomly assigned to experimental or control groups. The experimental groups received 10 acupuncture sessions over 4 weeks(Group A, n=20) or 20 sessions over 8 weeks(Group B, n=20) along with usual care. The acupoints were GB20, LI11, ST36, and SP6, bilaterally. The acupuncture groups were followed-up for an additional 12 weeks after acupuncture treatment. The control groups received usual care for 16 weeks(Group C, n=10) or 20 weeks(Group D, n=10). The outcomes were blood pressure, blood pressure control rates, lipid profile, and high-sensitivity C-reactive protein(hs-CRP). Results : After 4 weeks, DBP in the acupuncture groups(A+B) showed no significant decrease compared to the control group(C+D). However, after 8 weeks of acupuncture treatment, group B showed a significant decrease in DBP after acupuncture treatment and follow-up period compared to control group. Although there was no difference between the acupuncture and control groups in SBP after acupuncture treatment, group B showed a significant decrease in SBP compared to control group after follow-up period. Lipid profiles and hs-CRP did not differ significantly between acupuncture and control groups. Conclusions : Acupuncture treatment for 8 weeks showed the effect on prehypertension and mild hypertension. To verify the effect of acupuncture on blood pressure, rigorous trials including more participants are required.



Supported by : Korea Institute of Oriental Medicine


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