Anxiety and mood (대한불안의학회지)

Korean Academy of Anxiety Disorders (대한불안의학회)
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Impact of Comorbid Obsessive Compulsive Symptoms on Quality of Life in Stable Patients with Chronic Schizophrenia

안정화된 만성 조현병 환자에서 강박장애 증상이 삶의 질에 미치는 영향

  • Moon, Jung Yoon (Department of Psychiatry, Veterans Health Service Medical Center) ;
  • Kang, Sukhoon (Department of Psychiatry, Veterans Health Service Medical Center) ;
  • Seok, Jung-Ho (Departments of Psychiatry, Yonsei University College of Medicine) ;
  • Kim, Chan-Hyoung (Departments of Psychiatry, Yonsei University College of Medicine) ;
  • Kim, Tae Yong (Department of Psychiatry, Veterans Health Service Medical Center) ;
  • Choi, Jin Hee (Department of Psychiatry, Veterans Health Service Medical Center) ;
  • So, Hyong Seok (Department of Psychiatry, Veterans Health Service Medical Center)
  • 문정윤 (보훈공단 중앙보훈병원 정신건강의학과) ;
  • 강석훈 (보훈공단 중앙보훈병원 정신건강의학과) ;
  • 석정호 (연세대학교 의과대학 정신과학교실) ;
  • 김찬형 (연세대학교 의과대학 정신과학교실) ;
  • 김태용 (보훈공단 중앙보훈병원 정신건강의학과) ;
  • 최진희 (보훈공단 중앙보훈병원 정신건강의학과) ;
  • 소형석 (보훈공단 중앙보훈병원 정신건강의학과)
  • Received : 2017.09.07
  • Accepted : 2017.10.20
  • Published : 2017.10.31
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Abstract

Objective : This study aimed to evaluate the relationship between comorbid obsessive compulsive disorder (OCD) and quality of life in stable patients with schizophrenia. Methods : We interviewed 162 symptom-stable inpatients who have been on a constant dose of antipsychotics for at least 3 months prior and diagnosed as chronic schizophrenia. Subsequently, patients were classified according to the existence of OCD as evaluated using the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV). Further, all clinical and demographic data were collected and evaluated. To investigate potential interrelationships, the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), Korea-Positive and Negative Symptom Scale (K-PANSS), Korean Modification of the Scale to Measure Subjective Well-Being under Neuroleptic Treatment (KmSWN) and Korean Version Quality of Life Scale (K-QOLS) were performed. Independent t-test and Chi-square test were used to compare groups and regression analysis was done to assess the relationship between the Y-BOCS and quality of life. Results : Schizophrenia patients with OCD showed significantly earlier onset of schizophrenia, more severe psychiatric symptoms and lower quality of life, compared to those without comorbid OCD. OCD might be associated with lower quality of life in schizophrenia. Conclusion : Schizophrenia patients with OCD showed lower quality of life than those without OCD. In the treatment for schizophrenia, evaluation of OCD might be needed to improve their quality of life and social function.

Keywords

References

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