Journal of The Korean Society of Integrative Medicine (대한통합의학회지)

Korean Society of Integrative Medicine (대한통합의학회)
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The Effects of Stimulation of Acupuncture Point ST36 on Disuse Muscle Atrophy in Rats

흰쥐 발목관절고정으로 유발된 장딴지근 위축에 경혈점 자극이 미치는 효과

  • Kim, Bumhoi (Dept. of College of Korean Medicine, Dong-Eui University) ;
  • Lee, Taesik (Dept. of Physical Therapy, Dong-Eui Institute of Technology)
  • 김범회 (동의대학교 한의과대학 한의학과) ;
  • 이태식 (동의과학대학교 물리치료과)
  • Received : 2018.11.12
  • Accepted : 2018.12.14
  • Published : 2018.12.30
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Abstract

Purpose : The present study tested the hypothesis that acupressure at Zusanli(ST36) would attenuate immobilization-induced skeletal muscle atrophy. Methods : The left hind limb was immobilized using casting tape (ST36 group, n=10), and the animals were then treated daily with a pressure needle at ST36. Ten untreated animals with hind limb immobilization and no treatment served as a control group (n=10). After 2 weeks of immobilization, The body weight changes of rats were evaluated and the morphologies of the right and left gastrocnemius muscles in both the ST36 and control groups were assessed by hematoxylin and eosin staining. The levels of malondialdehyde (MDA) of gastrocnemius muscles were observed. Results : The acupressure at the accupoint of Zusanli conferred significant protection against reductions in left gastrocnemius muscle weights and average cross-sectional muscle areas in the ST36 group as compared with those in the control group. Moreover, the acupressure at the ST36 point significantly reduced malondialdehyde (MDA) activity in the gastrocnemius muscles as compared with that in the control group. Conclusion : These results suggest that acupressure at the accupoint of Zusanli provides protection against immobilization-induced muscle atrophy by decreasing MDA activity in gastrocnemius muscles.

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References

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