Journal of The Korean Society of Integrative Medicine (대한통합의학회지)

Korean Society of Integrative Medicine (대한통합의학회)
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Effect of Electrical Vagus Nerve Stimulation to Control Systemic Inflammation and Anti-Aging Hormone on Elder

미주신경 전기 자극이 노인의 항노화 호르몬과 전신적 염증에 미치는 효과

  • Moon, Hyunju (Vagus Nerve Research Center, Director of the Center) ;
  • Goo, Bongoh (Dept. of Physical Therapy, Catholic University of Pusan)
  • 문현주 (미주신경연구센터) ;
  • 구봉오 (부산가톨릭대학교 물리치료학과)
  • Received : 2018.08.30
  • Accepted : 2018.10.12
  • Published : 2018.12.30
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Abstract

Purpose : As age increases, a low-level systemic inflammatory state develops and the levels of anti-aging hormones decrease. The vagus nerve activates parasympathetic nerves and promotes sulfation and secretion of neurotransmitter in the brain. Therefore, the purpose of this study was to investigate the effects of electrical vagus nerve stimulation on systemic inflammation (CRP) and anti-aging hormone (DHEA-S) levels in elder people. Methods : A total of 30 healthy elder people participated in this study, randomly divided into two groups of 15 subjects. Electrical vagus nerve stimulation was applied to the experimental group for 4 weeks. CRP and DHEA-S levels were compared with those of the control group. Results : The CRP level was significantly lower in the experimental group than in the control group. In the experimental group, there was a significant decrease in CRP before and after the intervention. However, the DHEA-S level was not significantly different between groups. Conclusion : Electrical vagus nerve stimulation may alleviate the low-level systemic inflammatory state found in elderly people. These results suggest that it may have the effect of reducing the degenerative inflammatory diseases of the elderly and delaying aging.

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References

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