Korean Chemical Engineering Research

The Korean Institute of Chemical Engineers (한국화학공학회)
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Synergy Effect of Chlorhexidine and Essential Oils on Antimicrobial Activity in Dental Impression Materials

치과용 인상재에서의 클로르헥시딘과 에센셜 오일의 항균성능에 대한 상승효과

  • Lee, Kwang-Rae (Department of Chemical Engineering, Kangwon National University)
  • 이광래 (강원대학교 공과대학 화학공학과)
  • Received : 2017.07.31
  • Accepted : 2017.12.15
  • Published : 2018.04.01
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Abstract

There is growing concern about cross infection among the patients to patients, patients to staffs, and tools to patients in healthcare facilities, especially in dentistry. In this study, the most widely used dental impression materials were prepared and the synergy effect of Chlorhexidine and essential oil on antimicrobial activity was examined in the impression materials. Chlorhexidine concentration of 0.1 wt% and 0.5 wt% showed no antimicrobial activity on Escherichia coli (E. coli) and Candida albicans. At 1.0 wt% Chlorhexidine, 0% of E. coli and 34.7% of Candida albicans were survived. Bergamot (Essential oil) concentration of 0.5 wt% and 1.0 wt% showed no antimicrobial activity on E. coli. At 2.0 wt% Bergamot oil, 71.9% of E. coli were survived. Tea tree oil (Essential oil) of 0.5 wt% showed no antimicrobial activity on E. coli. At 1.0 wt% Tea tree oil, 11.2% of E. coli was survived. At 2.0 wt% Tea tree oil, no E. coli was survived. However, no E. coli was survived at the concentration of 0.8 wt% Bergamot with 0.3 wt% Chlorhexidine. At the concentration of 0.8 wt% Tea Tree oil with 0.3 wt% Chlorhexidine, 1.3% of E. coli were survived. The experimental results showed that the synergy effects between Chlorhexidine and essential oils on antimicrobial activity were prominent.

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References

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