International Journal of Oral Biology

  • 제43권2호
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  • Pages.83-91
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  • 2018
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  • 1226-7155(pISSN)
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  • 2287-6618(eISSN)
대한구강생물학회 (The Korean Academy of Oral Biology)
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Dentinal Tubules Occluding Effect Using Nonthermal Atmospheric Plasma

  • Lee, Chang Han (Department of Paediatric Dentistry, School of Dentistry, Pusan National University) ;
  • Kim, Young Min (Research and Development Center, Feagle Co., Ltd) ;
  • Kim, Gyoo Cheon (Research and Development Center, Feagle Co., Ltd) ;
  • Kim, Shin (Department of Paediatric Dentistry, School of Dentistry, Pusan National University)
  • 투고 : 2018.06.08
  • 심사 : 2018.06.23
  • 발행 : 2018.06.30
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초록

Nonthermal atmospheric plasma has been studied for its many biomedical effects, such as tooth bleaching, wound healing, and coagulation. In this study, the effects of dentinal tubules occlusion were investigated using fluoride-carboxymethyl cellulose (F-CMC) gel, nano-sized hydroxyapatite (n-HA), and nonthermal atmospheric plasma. Human dentin specimens were divided to 5 groups (group C, HA, HAF, HAP, and HAFP). Group HA was treated with n-HA, group HAF was treated with n-HA after a F-CMC gel application, group HAP was treated with n-HA after a plasma treatment and group HAFP was treated with n-HA after a plasma and F-CMC gel treatment. The occlusion of dentinal tubules was investigated using scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy (EDS), which shows Ca/P ratio. In the EDS results, a higher Ca/P ratio was shown in the groups including n-HA than in the control group. The specimens of group HAP and HAFP had a higher Ca/P ratio in retentivity. In the SEM results, there was not a significant difference in the amount of times applied. Therefore, this study suggests F-CMC gel and n-HA treatment using nonthermal atmospheric plasma will be a new treatment method for decreasing hypersensitivity.

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참고문헌

  1. Addy M. Tooth brushing, tooth wear and dentine hypersensitivity: are they associated? Int Dent J. 2005;55:261-267. https://doi.org/10.1111/j.1875-595X.2005.tb00063.x
  2. Brannstrom MA. A hydrodynamic mechanism in the transmission of pain producing stimuli through dentine. London: Pergamon Press; 1963.
  3. Hannig M, Hannig C. Nanomaterials in preventive dentistry. Nat Nanotechnol. 2010;5:565-569. doi:10.1038/nnano.2010.83.
  4. Yuan P, Shen X, Liu J, Hou Y, Zhu M, Huang J, Xu P. Effects of dentifrice containing hydroxyapatite on dentinal tubule occlusion and aqueous hexavalent chromium cations sorption: a preliminary study. PLos One. 2012;7:e45283. doi:10.1371/journal.pone.0045283.
  5. Hornby K, Evans M, Long M, Joiner AB, Laucello M, Salvaderi A. Enamel benefits of a new hydroxyapatite containing fluoride toothpaste. Int Dent J. 2009;59:325-331. doi:https://doi.org/10.1002/idj.2009.59.6s1.325.
  6. Adair SM. Evidence-based use of fluoride in contemporary pediatric dental practice. Pediatr Dent. 2006;28:133-142.
  7. Bea IH, Kim JM, Jeong TS, Kim S. Fluoride release and recharge of glass ionomer cements. J Korean Acad Pediatr Dent. 2005;32:136-143.
  8. Eronat C, Eronat N, Alpoz AR. Fluoride uptake by enamel in vitro following application of various topical fluoride preparations. J Clin Pediatr Dent. 1993;17:227-230.
  9. Kohli K, Houpt M, Shey Z. Fluoride uptake by proximal surfaces from professionally applied fluorides: an in vitro study. ASDC J Dent Child. 1997;64:28-31.
  10. Yaffe A, Zalkind M. The effect of topical application of fluoride on composite resin restoration. J Prosthet Dent. 1981;45:59-62. https://doi.org/10.1016/0022-3913(81)90013-5
  11. Choi WH, Kim EJ, Kim HJ, Kim JY, Nam SH. The effect of 1.23% APF gel on the esthetic restorative materials. J Korean Acad Pediatr Dent. 2006;33:281-289.
  12. Park SR, Hong JW, Lee HJ, Kim GC. Plasma medicine; how can nonthermal atmospheric plasma be applied to medicine? J Life Sci. 2013;23:838-846. https://doi.org/10.5352/JLS.2013.23.6.838
  13. Sladek REJ, Filoche SK, Sissons CH, Stoffels E. Treatment of Streptococcus mutans biofilms with a nonthermal atmospheric plasma. Lett Appl Microbiol. 2007;45:318-323. https://doi.org/10.1111/j.1472-765X.2007.02194.x
  14. Nastuta AV, Topala I, Grigoras C, Pohoata V, Popa G. Stimulation of wound healing by helium atmospheric pressure plasma treatment. J Phys D: Appl Phys. 2011; 44:105204. doi:https://doi.org/10.1088/0022-3727/44/10/105204.
  15. Lee HW, Kim GJ, Kim JM, Park JK, Lee JK, Kim GC. Tooth bleaching with nonthermal atmospheric pressure plasma. J Endod. 2009;35:587-591. doi:10.1016/j.joen.2009.01.008.
  16. Iza F, Lee JK, Kong MG. Electron kinetics in radio-frequency atmospheric-pressure microplasmas. Phys Rev Lett. 2007;99:075004. https://doi.org/10.1103/PhysRevLett.99.075004
  17. Wilson JM, Fry BW, Walton RE, Ganggarosa LP Sr. Fluoride level in dentin after iontophoresis of 2% NaF. J Dent Res. 1984;63:897-900. https://doi.org/10.1177/00220345840630061701
  18. Perioli L, Ambrogi V, Venezia L, Biovagnoli S, Pagano C, Rossi C. Formulation studies of benzydamine mucoadhesive formulations for vaginal administration. Drug Dev Ind Pharm. 2009;31:1-11. doi:10.1080/03639040802592435.
  19. Gaisford S, Beezer AE, Bishop AH, Walker M, Parsons D. An in vitro method for the quantitative determination of the antimicrobial efficacy of silver-containing wound dressing. Int J Pharm. 2009;366:261-267. doi:10.1016/j.ijpharm.2008.09.005.
  20. Lee HJ, Shon CH, Kim YS, Kim S, Kim GC, Kong MG. Degradation of adhesion molecules of G361 melanoma cells by a non-thermal atmospheric pressure microplasma. New J Phys. 2009;11:115026. doi:https://doi.org/10.1088/1367-2630/11/11/115026.
  21. Lim MY, Lum SO, Pho RS, Lee GP, Lim KC. An in vitro comparison of bleaching efficacy of 35% carbamide peroxide with established intacoronal bleaching agents. Int Endod J. 2004;37:483-488. https://doi.org/10.1111/j.1365-2591.2004.00829.x
  22. Lata S, Varghese NO, Varughese MJ. Remineralization potential of fluoride and amorphous calcium phosphate-casein phospho peptide on enamel lesions: an in vitro comparative evaluation. J Conserv Dent. 2010;13:42-46. doi:10.4103/0972-0707.62634.
  23. Furseth R. A study of experimentally exposed and fluoride treated dental cementum in pigs. Acta Odontol Scand. 1970;28:833-850. https://doi.org/10.3109/00016357009028249
  24. Farooq I, Imran Z, Farooq U, Leghari A, Ali H. Bioactive glass: a material for the future. Wolrd J Dent. 2012;3:199-201. doi:10.5005/jp-journals-10015-1156.
  25. Abis EG, Addy M, Adams D. Dentin hypersensitivity: a study of the patency of dentin tubules in sensitive and non-sensitive cervical dentin. J Clin Peroidontol. 1987;14:280-284. https://doi.org/10.1111/j.1600-051X.1987.tb01533.x
  26. Xu HH, Weir MD, Sun L. Nonocomposites with Ca and PO4 release: effects of reinforcement, dicalcium phosphate particle size and silanization. Dent Mater. 2007;23:1482-1491. https://doi.org/10.1016/j.dental.2007.01.002
  27. Suge T, Ishikawa K, Kawasaki A, Suzuki K, Matsuo T, Noiri Y, Imazato S, Ebisu S. Calcium phosphate precipitation method for the treatment of dentin hypersensitivity. Am J Dent. 2002;15:220-226.