- Volume 14 Issue 1
DOI QR Code
DENTAL TREATMENT OF A PATIENT WITH CATCH22 SYNDROME UNDER GENERAL ANESTHESIA: A CASE REPORT
CATCH22 syndrome 환아의 전신마취 하 치아우식 치료: 증례보고
- Kim, Min Jin (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Song, Ji-Soo (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Shin, Teo Jeon (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Kim, Young-Jae (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Kim, Jung-Wook (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Jang, Ki-Taeg (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Lee, Sang-Hoon (Department of Pediatric Dentistry, School of Dentistry, Seoul National University) ;
- Hyun, Hong-Keun (Department of Pediatric Dentistry, School of Dentistry, Seoul National University)
- 김민진 (서울대학교 치의학대학원 소아치과학교실) ;
- 송지수 (서울대학교 치의학대학원 소아치과학교실) ;
- 신터전 (서울대학교 치의학대학원 소아치과학교실) ;
- 김영재 (서울대학교 치의학대학원 소아치과학교실) ;
- 김정욱 (서울대학교 치의학대학원 소아치과학교실) ;
- 장기택 (서울대학교 치의학대학원 소아치과학교실) ;
- 이상훈 (서울대학교 치의학대학원 소아치과학교실) ;
- 현홍근 (서울대학교 치의학대학원 소아치과학교실)
- Received : 2018.06.19
- Accepted : 2018.06.27
- Published : 2018.06.30
CATCH22 syndrome or DiGeorge syndrome is a medical acronym of cardiac defects, abnormal facial appearances, thymic hypoplasia, cleft palate, and hypocalcemia. Patients with CATCH22 syndrome are susceptible to infection due to an absent or hypoplastic thymus and often have difficulties in maintaining good oral hygiene, which may require dental treatment. We present a case of dental treatment for the uncooperative child with CATCH22 syndrome under general anesthesia. A 4-year-old, 14.8 kg boy with CATCH22 syndrome visited Seoul National University Dental Hospital for dental check up. The patient had multiple caries requiring dental treatment. He experienced the corrective heart surgery due to Tetralogy of Fallot a few years ago. General anesthesia was planned because his heart rate and vital sign had shown unstable during the previous conscious sedation procedure. Dental restorative treatments were successfully performed and no complications were observed during and after the procedure. Safe and effective dental management of the patients with CATCH22 syndrome could be performed with the help of general anesthesia and careful monitoring.
- McDonald-McGinn DM, Emanuel BS, Zackai EH : 22q11.2 Deletion Syndrome, University of Washington, Seattle, 1-59, 2013.
- McDonald-McGinn DM, Sullivan KE : Chromosome 22q11.2 deletion syndrome (DiGeorge syndrome/velocardiofacial syndrome). Medicine, 90:1-18, 2011. https://doi.org/10.1097/MD.0b013e3182060469
- Kobrynski LJ, Sullivan KE : Velocardiofacial syndrome, DiGeorge syndrome: the chromosome 22q11.2 deletion syndromes. Lancet, 370:1443-1452, 2007. https://doi.org/10.1016/S0140-6736(07)61601-8
- Bassett AS, McDonald-McGinn DM, Vorstman J, et al. : Practical guidelines for managing patients with 22q11.2 deletion syndrome. J Pediatr, 159:332-339, 2011. https://doi.org/10.1016/j.jpeds.2011.02.039
- Perez E, Sullivan KE : Chromosome 22q11.2 deletion syndrome Digeorge and velocardiofacial syndrome. Curr Opin Pediatr, 14:678-683, 2002. https://doi.org/10.1097/00008480-200212000-00005
- Wilson DI, Burn J, Goodship J, et al. : DiGeorge syndrome: part of CATCH 22. J Med Genet, 30:852-856, 1993. https://doi.org/10.1136/jmg.30.10.852
- Kulan P, Pekiner FN, Akyuz S : Oral Manifestation and Dental Management of CATCH 22 Syndrome. Marmara Dent J, 1:46-48, 2013.
- Toka O, Karl M, Holst A, et al. : Dental aspects in patients with DiGeorge syndrome. Quintessence Int, 41:551-6, 2010.
- Ranggard L, Ostlund J, Nelson N, Noren JG : Clinical and histologic appearance in enamel of primary teeth from children with neonatal hypocalcemia induced by blood exchange transfusion. Acta Odontol Scand, 53:123-128, 1995. https://doi.org/10.3109/00016359509005958
- Driscoll DA, Budarf ML, Emanuel BS : A genetic etiology for DiGeorge syndrome: Consistent deletions and microdeletions of 22q11. Am J Hum Genet, 50:924-933, 1992.
- Klingberg G, Lingstrom P, Carlen A, et al. : Caries-related saliva properties in individuals with 22q11 deletion syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 103:497-504, 2007. https://doi.org/10.1016/j.tripleo.2006.09.018
- Borglum Jensen S, Jacobsen P, Illum F, et al. : Oral findings in DiGeorge syndrome. Int J Oral Surg, 12:250-254, 1983. https://doi.org/10.1016/S0300-9785(83)80050-7
- Klingberg G, Dietz W, Noren JG, et al. : Morphological appearance and chemical composition of enamel in primary teeth from patients with 22q11 deletion syndrome. Eur J Oral Sci, 113:303-311, 2005. https://doi.org/10.1111/j.1600-0722.2005.00223.x
- 김혜순, 김호성, 서정욱 등. : Chromosome 22q11 결손을 가진 CATCH 22 환자의 임상 고찰, 소아과, 38:1603-1608, 1995.
- Kim MS, Lee SE, Choi SC, et al. : Dental Treatment of Children with CATCH 22 Syndrome: Case Report. J Korean Dent Soc Anesthesiol, 13:13-18, 2013.
- 유혜영, 조은경, 이재호 등. : CATCH 22 증후군의 면역학적 특성, 소아과, 43:1423-1429, 2000.
- Yotsui-Tsuchimochi H, Higa K, Shono S, et al. : Anesthetic management of a child with chromosome 22q11 deletion syndrome. Paediatr Anaesth, 16:454-457, 2006. https://doi.org/10.1111/j.1460-9592.2005.01716.x
- Anaesthesia recommendations for patients suffering from 22q11.2 deletion syndrome. Available from URL: https://www.orpha.net/data/patho/Ans/en/22q11.2Deletion-Syndrome_DE_en_ANS_ORPHA567.pdf (Accessed on May 31,2018).