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Association Metabolic Syndrome with Sarcopenia in Korean Stroke Patients : Korean National Health and Nutrition Examination Survey Data(2008-2011)

뇌졸중 유병자의 대사증후군과 근감소증의 관련성: 국민건강조사(2008년-2011년)자료를 근거로

  • Received : 2018.06.12
  • Accepted : 2018.10.19
  • Published : 2018.10.28

Abstract

The purpose of this study was to examine the association metabolic syndrome with sarcopenia in Korean stroke patients. We used the Korean National Health and Nutrition Examination Survey data from 2008 to 2011 and enrolled a total of 316 stroke patients older than 40 years. Data were analyzed by Rao-Scott ${\chi}^2-test$, generalized linear model and composite sample multiple logistic regression. The prevalence of sarcopenia was 47.3% in men and 46.3% in women. The prevalence of metabolic syndrome was 50.3% in men and 73.6% in women. After adjusting for age, smoking status, alcohol consumption, exercise, education, income, sroke sequla and stroke duration, men with sarcopenia had increased risk of metabolic syndrome (95% CI: 2.454-18.482, p<.001). This finding can be used to develop evidence-based health promotion program to prevent stroke reccurance for stroke patients.

본 연구는 국민건강영양조사의 자료를 활용하여 뇌졸중 유병자의 근감소증 및 대사증후군의 유병률과 대사증후군과 근감소증의 관련성을 알아보고자 수행되었다. 2008년 하반기에서 2011년 상반기까지 국민건강영양조사에서 만 40세 이상 뇌졸중 유병자 316명(남자 164명, 여자 152명)을 최종 연구대상으로 선정하였다. 근감소증 유무에 따른 연구대상자의 일반적인 특성과 대사증후군 요소별 차이는 Rao-Scott 카이검정과 일반선형모형을 이용하였고, 대사증후군과 근감소증의 관련성을 분석하기 위해서 복합표본 다중 로지스틱 회귀분석을 실시하였다. 연구 결과 뇌졸중 유병자에게서 근감소증 유병률은 남자 47.3%, 여자 46.3%로 나타났고, 대사증후군 유병률은 남자, 여자 각각 50.6%, 73.7%로 나타났으며, 남자에게서 근감소증이 없는 군에 비하여 근감소증이 있는 군이 대사증후군 유병 가능성이 6.734배 높은 것으로 나타났다(95% CI: 2.454-18.482, p<.001). 본 연구결과, 남자 뇌졸중 유병자에게서 근감소증은 대사증후군의 독립적인 위험요인임을 확인할 수 있었다. 그러므로 뇌졸중 유병자의 뇌졸중 재발을 예방하기 위하여 재활치료 시작단계 교육프로그램에 뇌졸중 재발 요인인 대사증후군을 적극적으로 예방 및 관리하기 위한 구체적인 전략으로 근감소증 예방의 중요성과 방법이 포함될 필요가 있다고 본다.

Keywords

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