The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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The Literary Trends of Herbal Prescription Ukgan-san and its Application in Modern Traditional Korean Medicine

동의보감에 수록되지 않았던 억간산의 문헌상 흐름과 현대 한의학에서의 응용 현황

  • Cho, Ki-Ho (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University) ;
  • Kim, Tae-Hun (College of Korean Medicine, Kyung Hee University Korean Medicine Clinical Trial Center, Kyung Hee University Korean Medicine Hospital) ;
  • Jin, Chul (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University) ;
  • Lee, Ji-Eun (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University) ;
  • Kwon, Seungwon (Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University)
  • 조기호 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 김태훈 (경희대학교 한의약임상시험센터) ;
  • 진철 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 이지은 (경희대학교 한의과대학 순환신경내과학교실) ;
  • 권승원 (경희대학교 한의과대학 순환신경내과학교실)
  • Received : 2018.08.22
  • Accepted : 2018.09.09
  • Published : 2018.09.30
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Abstract

Objectives: Ukgan-san does not appear in Traditional Korean Medicine classics. However, it has been used in research and clinical applications in Korea. In this paper, we are aiming to examine the records concerned with Ukgan-san to the present, and announce the present usage state in Korea. Methods: We searched and summarized the contents of previous medical books about Ukgan-san. In order to investigate the current status of utilization of Ukgan-san in Korea, a bibliographic database of Korea, a database of clinical researches, and a database of pharmaceuticals of the Korea Food and Drug Administration were searched. Results: As a result of searching Ukgan-san related documents, Ukgan-san has been developed in China (Ming dynasty). However, its clinical application has been expanded by modern Japanese kampo medicine doctors. In Korea, cases of Parkinson's disease, other movement disorders, and psychiatric disorders have been reported, and randomized controlled trials had been done and planned. In addition, some extracts which are consisted of Ukgan-san are also available. Conclusions: In Korea, Ukgan-san has been influenced by Japan and has been used for clinical and research purposes. The utilization rate in Korea is still small, but the utilization rate will increase according to the results of clinical studies.

Keywords

References

  1. Chinese Text Project. Boyeongchwalyo (保嬰撮要). 2016. Available at: URL:https://ctext.org/wiki.pl?if=gb&res=664599 Accessed August 15, 2018.
  2. Kinebuchi A, Kosoto H, Kimura Y, Fujii Y, Inaki K, Nagao S, et al. Yokukansan Desecriptions in the Original Texts. Kampo Med. 2014;65(3):180-4. https://doi.org/10.3937/kampomed.65.180
  3. Chinese Text Project. Seolsiuian (薛氏醫案). 2016. Available at: URL:https://ctext.org/wiki.pl?if=gb&res=942002 Accessed August 15, 2018.
  4. 후웨이캉(傅維康). 카와이 마사히사(川井正久), 카와이 쥬코우(川合重孝), 야마모토 츠네히사(山本恒久) 역. 中国医学の歴史. 이치카와:동양학술출판사(東洋學術出版社). 1997:462-3.(일본어)
  5. 진대순. 맹웅재, 박현국, 박경남, 김남일, 신영일, 김용진, 안상우, 김훈, 김홍균, 차웅석 역. 각가학설: 중국편. 서울:대성의학사. 2001:281-296.
  6. Chinese Text Project. Jeungchijunseung (證治準繩). 2016. Available at: URL:https://ctext.org/wiki.pl?if=gb&res=227348 Accessed August 15, 2018.
  7. Korea Institute of Oriental Medicine. Korean traditional medicine classical DB Gyeongakjeonseo (景岳全書) volume 62. 2018. Availabe at: URL:https://mediclassics.kr/books/139/volume/62 Accessed August 15, 2018.
  8. 후쿠이 후테이(福井楓亭). 방독변해(方讀弁解). 도쿄:명저출판(名著出版). 1981:172-3. (일본어)
  9. 하세가와 미츠토. 물오약실방함구결석의(勿誤藥 室方函口訣釋義). 오사카:소겐샤(創元社). 1994:265-7. (일본어)
  10. 야가즈 도메이. 임상응용 한방처방해설(臨床應用 漢方處方解說). 오사카:소겐샤(創元社). 1994:599-605. (일본어)
  11. 오츠카 케이세츠, 야가즈 도메이, 시미즈 토타로. 한방진료의전(漢方診療醫典). 도쿄:난잔도(南山堂). 1986:424-6. (일본어)
  12. 일약연한방전문위원회. 일반용 한방처방 매뉴얼 (一般用漢方處方の手引き). 도쿄:약업시보사(藥業時報社). 1995:244-7. (일본어)
  13. 일본한방생약제제협회. 신 일반용 한방처방 매뉴얼(新一 般用漢方處方の手引き). 도쿄:주식회사 지호우(株式會社 じほう). 2014:298-300. (일본어)
  14. Japanese Society of Neurology. Clinical Practice Guidelines of Dementia 2017 (認知症疾患診療ガイドライン2017). 2017. Availabe at: URL:https://www.neurology-jp.org/guidelinem/nintisyo_2017.html (Japanese) Accessed August 15, 2018.
  15. Japanese Society of Geriatric Medicine. Safety Drug Therapy Guidelines for the Elderly 2015 (高齢者の安全な薬物療法ガイドライン2015). Tokyo; Medical Review Co. Ltd. 2015:141. (Japanese)
  16. Japanese Society of Neurology. Parkinson's disease treatment guidelines 2011 (パーキンソン病治療ガイドライン2011). Tokyo; Igakushoin. 2011:165. (Japanese)
  17. Kim KN, Cho SH. Review of Clinical Trials about Herbal Medicine for Vascular Dementia. J of Oriental Neuropsychiatry. 2012;23(4):37-48. https://doi.org/10.7231/jon.2012.23.4.037
  18. Lee YE, Lee DH, Lee JH, Lu HY, Cho SY, Park JM, et al. Three Case Reports of Postural Instability and Gait Difficulty in Parkinson's Disease Patients Treated with Korean and Western Medicine. Korean Jounral of Acupuncture. 2014; 31(1):40-47. https://doi.org/10.14406/acu.2014.008
  19. Yang SB, Kim YJ, Lee HM, Lee HJ, Cho SY, Park JM, et al. Effects of Korean Medicine on Patients with Idiopathic Parkinson's Disease: A Retrospective Study. J Int Korean Med. 2016;37(4):653-660. https://doi.org/10.22246/jikm.2016.37.4.653
  20. Kim YJ, Yang SB, Kim JH, Lee BY, Cho SY, Park SU, et al. Case of Drug-Induced Parkinsonism Treated with Traditional Korean Medicine. J Int Korean Med. 2016;3\(2):381-388.
  21. Park MJ, Lee MR, Kim GM, Cho KH, Moon SK, Kwon S, et al. A Case Report of a Patient with Lewy's Body Dementia and Insomnia Treated with Korean Medicine. J Int Korean Med. 2017;38(2):146-151. https://doi.org/10.22246/jikm.2017.38.2.146
  22. Kim SY, Park JH, Ahn JH, Jo JJ, Lee SM, Kang JW, et al. A Case Report of a Right-sided Hemichorea Patient Diagnosed with Chorea Hyperglycemia Basal Ganglia Syndrome : A Combined Western-Korean Medicine Approach. The Acupuncture. 2016;33(1):117-125.
  23. Park MC, Hong SU. Two cases of the treatment of hemifacial spasm improved by Ukgansangamibang(抑肝散加味方) and moxa-treatment. J Korean Orient Med Ophtal & Oto & Derm. 2007;20 (3):236-242.
  24. Lee MR, Kim SB, Woo JM, Kang AR, Cho KH, Moon SK, et al. Case Study of a Patient with Dystonia Due to Dystonic Cerebral Palsy Treated with Traditional Korean Medicine. J Int Korean Med. 2016;37(2):257-264.
  25. Park SM, Kang BG, Lee JW, Na RH, Bang CH, Gang SO, et al. Clinical Case Report of Restless Leg Syndrome in Ischemic Stroke Patients. Korean J Oriental Physiol & Pathol. 2008;22(4):975-981.
  26. Kim JH, Oh YL, Lee JH, Kim TH, Lyu YS, Kang HW. A Case Report of Typical Oriental Medical Therapy in Combination with Neurofeedback on ADHD Chil. J of Oriental Neuropsychiatry. 2006;17(3):157-164.
  27. Seo JH, Kang HS, Kim JY, Sung WY, Na YJ, Kim JW. A Case Report of a Patient with Weakness of Heart and Gall bladder type Somatization disorder induced by Stress. J of Oriental Neuropsychiatry. 2007;18(3):249-260.
  28. Jung H, Sung WY, Lee S, Son JH, Hang SH. A clinical report of a patient with Tourett's disorder. J of Oriental Neuropsychiatry. 2003; 14(2):213-218.
  29. Hyun WC, Lee SR. Studies on the Effect of AntiConvulsion and Analgesic by Ukgansan and Ukgansangami. J of Oreintal Neuropsychiatry. 1994;5(1):69-79.
  30. Kim KS, Sung GK, Moon BS. An Experimental Study on the Antiepileptic Effects of Ukgansan. KIMS. 1998;19(1):57-72.
  31. Cho MY, Shin YJ, Ha YJ, Woo C, Kim TJ, You JY, et al. Protective Effects of Ukgan-san in $CoCl_2$-induced Cell Death of C6 Glial Cells. Korean J Orient Int Med.2013;34(2):178-191.
  32. Kim SM. Effects of Ukgan-san on the L-thyroxineindcued Rat Hyperthyroidism. Korean J Oriental Physiology & Pathology. 2012;26(5):679-686.
  33. Shim YH, Park JY, Choi WW, Min IK, Park SU, Jung WS, et al. Herbal medicine treatment for drug-induced parkinsonism. J Altern Complement Med. 2015 May;21(5):273-80. https://doi.org/10.1089/acm.2014.0124
  34. KCDC and National Research Institute of Health. CRIS(Clinical Research Information Service). 2018. Availabe from: URL:https://cris.nih.go.kr/cris/index.jsp Accessed August 15, 2018.
  35. Korea Food & Drug Administration. KFDA Online Medicine Library. 2018. Availabe at: URL: http://drug.mfds.go.kr/html Accessed August 15, 2018.

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