Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Effects of Laser and Electro Acupuncture Treatment with GB30·GB34 on Change in Arthritis Rat

환도·양릉천 레이저 및 전침이 관절염에 미치는 영향

  • Kim, Mirae (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Lee, Yumi (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Choi, Donghee (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Youn, Daehwan (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Na, Changsu (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University)
  • 김미래 (동신대학교 한의과대학 경락경혈학교실) ;
  • 이유미 (동신대학교 한의과대학 경락경혈학교실) ;
  • 최동희 (동신대학교 한의과대학 경락경혈학교실) ;
  • 윤대환 (동신대학교 한의과대학 경락경혈학교실) ;
  • 나창수 (동신대학교 한의과대학 경락경혈학교실)
  • Received : 2019.08.18
  • Accepted : 2019.09.26
  • Published : 2019.12.27
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Abstract

Objectives : This study aimed to investigate the effects of electroacupuncture (EA), the laser acupuncture (LA) and the combination therapy (LA+EA) in a collagenase-induced osteoarthritis rat model. Methods : Osteoarthritis rat model was induced by injection of collagenase into left lower articular cavity (50 μl to knee and 10 μl to ankle). In order to assess the anti-osteoarthritic effects of EA, the 650 nm LA and 650 nm LA+EA, the histopathological findings and plantar withdrawal responses were analyzed. Results : All of the treatment methods used in this study were effective in reducing pain. All treatment groups were effective in decreasing inflammatory cytokines of TNF-a and IL-6; the 650 nm LA and 650 nm LA+EA groups significantly reduced IL-1β. Conclusions : 650 nm LA and EA inhibit the production of collagenase-induced inflammatory mediators of osteoarthritis.

Keywords

References

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