DOI QR코드

DOI QR Code

사람 악골골수염 병소에서 분리된 Cutibacterium acnes KCOM 1315의 유전체 염기서열 완전 해독

Complete genome sequence of Cutibacterium acnes KCOM 1315 isolated from a human jaw osteomyelitis lesion

  • 박순낭 (조선대학교 치과대학 구강생화학교실 및 한국구강미생물자원은행) ;
  • 박정환 (조선대학교 치과대학 치의학과) ;
  • 임윤경 (조선대학교 치과대학 구강생화학교실 및 한국구강미생물자원은행) ;
  • 신자영 (마크로젠) ;
  • 노한성 (마크로젠) ;
  • 국중기 (조선대학교 치과대학 구강생화학교실 및 한국구강미생물자원은행)
  • Park, Soon-Nang (Korean Collection for Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University) ;
  • Park, Jeong-Hwan (School of Dentistry, Chosun University) ;
  • Lim, Yun Kyong (Korean Collection for Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University) ;
  • Shin, Ja Young (Macrogen Inc.) ;
  • Roh, Hanseong (Macrogen Inc.) ;
  • Kook, Joong-Ki (Korean Collection for Oral Microbiology and Department of Oral Biochemistry, School of Dentistry, Chosun University)
  • 투고 : 2018.11.21
  • 심사 : 2018.12.20
  • 발행 : 2019.03.31

초록

Cutibacterium acnes는 사람의 피부, 결막, 장관, 외이도 및 구강의 정상 세균 총의 하나이다. 이 세균 종은 여드름, 심내막염 감염, 유육종증, 뇌 농양, 치주염 및 골수염과 관련된 기회감 염성병원균으로 확인되었다. C. acnes KCOM 1315 (= ChDC KB81)는 사람 악골골수염 병소로부터 분리되었다. 여기에서 C. acnes KCOM 1315 균주 완전 유전체 염기서열을 해독하여 보고한다.

Cutibacterium acnes is a member of normal flora of human skin, conjunctiva, intestinal tract, the external auditory canal as well as oral cavity. It has been identified as an opportunistic pathogen related to acne vulagris, endocarditis infections, sarcoidosis, brain abscess, periodontitis, and osteomyelitis of the humerus. C. acnes KCOM 1315 (= ChDC KB81) was isolated from a human jaw osteomyelitis lesion. Here, we present the complete genome sequence of C. acnes KCOM 1315.

키워드

MSMHBQ_2019_v55n1_64_f0001.png 이미지

Fig. 1. Circular map of genome of Cutibacterium acnes KCOM 1315.

Table 1. Genome features of Cutibacterium acnes KCOM 1315

MSMHBQ_2019_v55n1_64_t0001.png 이미지

참고문헌

  1. Aubin GG, Lavigne JP, Foucher Y, Delliere S, Lepelletier D, Gouin F, and Corvec S. 2017. Tropism and virulence of Cutibacterium (formerly Propionibacterium) acnes involved in implant-associated infection. Anaerobe 47, 73-78. https://doi.org/10.1016/j.anaerobe.2017.04.009
  2. Cho E, Park SN, Lim YK, Shin Y, Paek J, Hwang CH, Chang YH, and Kook JK. 2015. Fusobacterium hwasookii sp. nov., isolated from a human periodontitis lesion. Curr. Microbiol. 70, 169-175. https://doi.org/10.1007/s00284-014-0692-7
  3. Gunthard H, Hany A, Turina M, and Wust J. 1994. Propionibacterium acnes as a cause of aggressive aortic valve endocarditis and importance of tissue grinding: case report and review. J. Clin. Microbiol. 32, 3043-3045. https://doi.org/10.1128/JCM.32.12.3043-3045.1994
  4. Leyden JJ. 2001. The evolving role of Propionibacterium acnes in acne. Semin. Cutan. Med. Surg. 20, 139-143. https://doi.org/10.1053/sder.2001.28207
  5. McDowell A, Patrick S, Eishi Y, Lambert P, and Eady A. 2013. Propionibacterium acnes in human health and disease. Biomed. Res. Int. 2013, 493564.
  6. Narita M, Shibahara T, Takano N, Fujii R, Okuda K, and Ishihara K. 2016. Antimicrobial susceptibility of microorganisms isolated from periapical periodontitis lesions. Bull. Tokyo Dent. Coll. 57, 133-142. https://doi.org/10.2209/tdcpublication.2015-0018
  7. Niazi SA, Al Kharusi HS, Patel S, Bruce K, Beighton D, Foschi F, and Mannocci F. 2016. Isolation of Propionibacterium acnes among the microbiota of primary endodontic infections with and without intraoral communication. Clin. Oral Investig. 20, 2149-2160. https://doi.org/10.1007/s00784-016-1739-x
  8. Sainani NA, Rafeek H, Locati J, Penn R, and Washburn R. 2015. Osteomyelitis of the humerus caused by Propionibacterium acnes. J. La. State Med. Soc. 167, 153-154.
  9. Scholz CF and Kilian M. 2016. The natural history of cutaneous propionibacteria, and reclassification of selected species within the genus Propionibacterium to the proposed novel genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov. Int. J. Syst. Evol. Microbiol. 66, 4422-4432. https://doi.org/10.1099/ijsem.0.001367
  10. Tatusova T, DiCuccio M, Badretdin A, Chetvernin V, Nawrocki EP, Zaslavsky L, Lomsadze A, Pruitt KD, Borodovsky M, and Ostell J. 2016. NCBI prokaryotic genome annotation pipeline. Nucleic Acids Res. 44, 6614-6624. https://doi.org/10.1093/nar/gkw569
  11. Walker BJ, Abeel T, Shea T, Priest M, Abouelliel A, Sakthikumar S, Cuomo CA, Zeng Q, Wortman J, Young SK, et al. 2014. Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement. PLoS One 9, e112963. https://doi.org/10.1371/journal.pone.0112963
  12. Zaffiri L, Abdulmassih R, Boyaji S, Bagh I, Campbell AR, and Loehrke ME. 2013. Brain abscess induced by Propionibacterium acnes in a patient with severe chronic sinusitis. New Microbiol. 36, 325-329.
  13. Zhou Y, Hu Y, and Li H. 2013. Role of Propionibacterium acnes in sarcoidosis: a meta-analysis. Sarcoidosis Vasc. Diffuse Lung Dis. 30, 262-267.