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Bone Involvement of Diffuse Large B Cell Lymphoma (DLBCL) Showing Unusual Manifestations Mimicking Chronic Osteomyelitis in a 58-Year-Old Man: Case Report and Clinical Application of Diffusion Weighted Magnetic Resonance Imaging

  • Received : 2019.05.20
  • Accepted : 2019.07.29
  • Published : 2019.09.30

Abstract

This study presents a case of diffuse large B cell lymphoma (DLBCL) in a 58-year-old man showing unusual manifestations mimicking chronic osteomyelitis. In this case review, we describe the imaging findings of DLBCL which mimics chronic osteomyelitis and review existing reports regarding the differential diagnosis of bone involvement of lymphoma and osteomyelitis through imaging and laboratory findings and diffusion-weighted magnetic resonance imaging (DWI) such as the advanced MRI sequence.

Keywords

References

  1. Kumar V, Abbas A, Fausto N, Aster J. Robbins and cotran pathologic basis of disease. 8th ed. Philadelphia, PA: Saunders/Elsevier, 2010:606-607
  2. Krishnan A, Shirkhoda A, Tehranzadeh J, Armin AR, Irwin R, Les K. Primary bone lymphoma: radiographic-MR imaging correlation. Radiographics 2003;23:1371-1383; discussion 1384-1377 https://doi.org/10.1148/rg.236025056
  3. Jennin F, Bousson V, Parlier C, Jomaah N, Khanine V, Laredo JD. Bony sequestrum: a radiologic review. Skeletal Radiol 2011;40:963-975 https://doi.org/10.1007/s00256-010-0975-4
  4. Markanday A. Acute phase reactants in infections: evidence-based review and a guide for clinicians. Open Forum Infect Dis 2015;2:ofv098 https://doi.org/10.1093/ofid/ofv098
  5. Trichopoulos D, Psaltopoulou T, Orfanos P, Trichopoulou A, Boffetta P. Plasma C-reactive protein and risk of cancer: a prospective study from Greece. Cancer Epidemiol Biomarkers Prev 2006;15:381-384 https://doi.org/10.1158/1055-9965.EPI-05-0626
  6. Wu S, Zhou Y, Hua HY, et al. Inflammation marker ESR is effective in predicting outcome of diffuse large B-cell lymphoma. BMC Cancer 2018;18:997 https://doi.org/10.1186/s12885-018-4914-4
  7. Filograna L, Magarelli N, Cellini F, et al. Diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADC) values for detection of malignant vertebral bone marrow lesions. Eur Rev Med Pharmacol Sci 2018;22:590-597
  8. Wu X, Pertovaara H, Dastidar P, et al. ADC measurements in diffuse large B-cell lymphoma and follicular lymphoma: a DWI and cellularity study. Eur J Radiol 2013;82:e158-164 https://doi.org/10.1016/j.ejrad.2012.11.021
  9. Ozgen B, Oguz KK, Cila A. Diffusion MR imaging features of skull base osteomyelitis compared with skull base malignancy. AJNR Am J Neuroradiol 2011;32:179-184 https://doi.org/10.3174/ajnr.A2237
  10. Abdel Razek AAK, Samir S. Diagnostic performance of diffusion-weighted MR imaging in differentiation of diabetic osteoarthropathy and osteomyelitis in diabetic foot. Eur J Radiol 2017;89:221-225 https://doi.org/10.1016/j.ejrad.2017.02.015