Journal of the Korean Magnetic Resonance Society (한국자기공명학회논문지)

Korean Magnetic Resonance Society (한국자기공명학회)
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Solvent-localized in-situ NMR Monitoring by Intermolecular Single-quantum Coherence Study

  • Cha, Jin Wook (Natural Product Informatics Research Center, KIST Gangneung Institute of Natural Products) ;
  • Park, Sunghyouk (Natural Product Research Institute, College of Pharmacy, Seoul National University)
  • Received : 2020.12.11
  • Accepted : 2020.12.18
  • Published : 2020.12.20
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Abstract

A new NMR method to monitor solvent-localized NMR signals in the two-phase liquid system is suggested. This method based on intermolecular single-quantum coherence (iSQC). Here, we exploited the feature of the local action of distant dipolar field (DDF) effect in order to filter out specific NMR signals dissolved in different solvents. This solvent specific iSQC spectroscopy was carried out on a model two-phase liquid system (D-glucose in water/palmitic acid in chloroform), and showed solvent-localized NMR signals. We believe our approaches might be useful in metabolic analysis such as two-phase liquid extraction scheme for labile chemical species.

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