Chemical Constituents Isolated from the Moss-derived Fungus Talaromyces sp.

All plants in natural ecosystems are living in symbiosis with endophytes. Recently, there has been an increasing interest in endophytes since these organisms can interact with the hosts and produce various structurally or biologically interesting molecules. This study aimed to identify these molecules from endophytes. Chemical investigation of Climacium dendroides-derived fungus Talaromyces sp. resulted in the isolation of two diphenyl ether derivatives, purpactin A (1) and penicillide (2), and two steroids, dankasterone A (3) and calvasterol B (4). The structures of the compounds were identified via extensive spectroscopic and spectrometric methods. Four compounds did not show any antioxidative activities in the on-line antioxidant activity screening system.