Journal of the Korea Academia-Industrial cooperation Society (한국산학기술학회논문지)

The Korea Academia-Industrial cooperation Society (한국산학기술학회)
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The evaluation of borage oil to use in pet foods

반려견 건강증진을 위한 보라지유 활용 가능성 평가

  • Kim, Min ji (National Institute of Animal Science, Rural Development Administration) ;
  • Seo, Kangmin (National Institute of Animal Science, Rural Development Administration) ;
  • Chun, Ju Lan (National Institute of Animal Science, Rural Development Administration) ;
  • Jeon, Jung Hwan (National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Chan Ho (National Institute of Animal Science, Rural Development Administration) ;
  • Jung, Ji Yeon (National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Ki Hyun (National Institute of Animal Science, Rural Development Administration)
  • 김민지 (농촌진흥청 국립축산과학원) ;
  • 서강민 (농촌진흥청 국립축산과학원) ;
  • 천주란 (농촌진흥청 국립축산과학원) ;
  • 전중환 (농촌진흥청 국립축산과학원) ;
  • 김찬호 (농촌진흥청 국립축산과학원) ;
  • 정지연 (농촌진흥청 국립축산과학원) ;
  • 김기현 (농촌진흥청 국립축산과학원)
  • Received : 2020.10.05
  • Accepted : 2020.12.04
  • Published : 2020.12.31
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Abstract

The purpose of this study was to investigate the safety and anti-inflammatory effects of borage oil on dogs. Twelve dogs were fed on a commercial diet of 1% or 2% borage oil alone for twelve weeks. To assess safety, the changes in body weight, blood cells, and immune-related cytokines were analyzed. The results showed that there was no significant difference in body weight, complete blood count (CBC), and immunomodulatory cytokines between the dogs fed with diets without or with borage oil. Also, there was no change in transepidermal water loss (TEWL). However, the amount of lactate dehydrogenase (LDH) was reduced significantly in the dogs fed on a borage oil diet. In summary, the addition of borage oil to pet food did not result in any significant health issues. Moreover, borage oil could contribute to a reduction in cell damage in aged dogs although it did not decrease TEWL. Therefore, borage oil could be safe for use in pet foods.

본 연구에서는 반려견의 건강증진을 위해 보라지유를 사료에 혼합하여 급여하였을 경우 사료로써의 안전성을 평가하고 염증완화 효능이 있는지 알아보았다. 총 12마리의 공시견을 대상으로 보라지유 1% 또는 2% 함유된 사료를 12주간 급여 실시한 후 혈액 생화학, 혈액 세포, 사이토카인 등의 안전성 평가 실험을 실시하였다. 또한 경피 수분 손실도를 측정하여 피부 건강에 미치는 보라지유의 효능을 평가하였다. 본 급여 시험의 결과, 보라지유는 반려견의 체중, 혈액세포, 면역관련 사이토카인에 영향을 미치지 않는 것으로 나타났다. 그리고, 경피 수분 손실도 측정 결과 역시 유의적인 차이를 보이지 않았다. 하지만, 혈액 내 젖산탈수소효소의 농도는 보라지유 함유 사료를 먹기 전과 비교하여 유의적으로 감소한 것을 확인하였다. 본 실험을 통해, 보라지유를 섭취하였을 경우 반려견에서 체중감소 및 혈액 지표 이상 등의 문제점을 야기하지 않고, 오히려 체내 세포 손상 정도를 감소시키는 효과의 가능성을 확인하였다. 본 연구 결과를 통해, 보라지유가 반려견 사료원료로써 안전하게 활용될 수 있을 것으로 보인다.

Keywords

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