Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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The Effects of Acupuncture at Heart and Kidney Meridian on Mitochondrial Respiratory Chain Complexes Activities in Rats

심경, 신경의 오수혈 침자가 Mitochondrial Respiratory Chain Complexes에 미치는 영향

  • Choi, Donghee (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Lee, Yumi (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Kim, Mirae (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Park, Jeonghye (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Kim, Hyeran (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Na, Changsu (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University) ;
  • Youn, Daehwan (Department of Acupoint & Meridian, College of Korean Medicine, Dongshin University)
  • 최동희 (동신대학교 한의과대학 경락경혈학교실) ;
  • 이유미 (동신대학교 한의과대학 경락경혈학교실) ;
  • 김미래 (동신대학교 한의과대학 경락경혈학교실) ;
  • 박정혜 (동신대학교 한의과대학 경락경혈학교실) ;
  • 김혜란 (동신대학교 한의과대학 경락경혈학교실) ;
  • 나창수 (동신대학교 한의과대학 경락경혈학교실) ;
  • 윤대환 (동신대학교 한의과대학 경락경혈학교실)
  • Received : 2020.02.17
  • Accepted : 2020.03.17
  • Published : 2020.03.27
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Abstract

Objectives : Mitochondria are typically known as intracellular double membrane-bound structures that supply energy for intracellular metabolism including Krebs cycle and beta-oxidation. Also, acupuncture has been known to stimulate the flow of energy. To explore the effect of acupuncture on the mitochondrial respiratory chain activities in rat's heart and kidneys, the activities of mitochondrial respiratory chain complexes I to IV were observed. Methods : The rats were divided into 11 groups; Normal (no acupuncture treatment and under anesthesia for 10 min), heart meridian five-transport-points (acupuncture treatment at HT9, HT8, HT7, HT4 and HT3 under anesthesia for 10 min), and kidney meridian five-transport-points (acupuncture treatment at KI1, KI2, KI3, KI7 and KI10 under anesthesia for 10 min). All rats were sacrificed and the heart and kidneys were examined for the changes of respiratory chain activities. Results : Acupuncture at HT7 increased the activity of succinate dehydrogenase; acupuncture at KI2 increased the activity of ubiquinol cytochrome C oxidoreductase; and acupuncture at HT9, HT8, HT3 and KI1 increased activities of cytochrome C oxidase. Conclusions : Acupuncture assists mitochondrial repiratory chain activity via the Cytochrome C oxidase signaling pathway in heart and kidney of rats.

Keywords

References

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