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Manufacturing a Functional Bolus Using a 3D printer in Radiation Therapy

방사선치료에서 3D 프린터를 이용한 기능적 조직보상체의 제작

  • Lee, Yi-Seong (Dept. of Radiation Oncology, Catholic Kwandong University International St. Mary's Hospital) ;
  • Kim, Jeong-Koo (Dept. of Radiological Science, Hanseo University)
  • 이이성 (가톨릭관동대학교 국제성모병원 방사선종양학과) ;
  • 김정구 (한서대학교 방사선학과)
  • Received : 2020.01.15
  • Accepted : 2020.02.28
  • Published : 2020.02.28

Abstract

Commercial plate bolus is generally used for treatment of surface tumor and required surface dose. We fabricated 3D-printed bolus by using 3D printing technology and usability of 3D-printed bolus was evaluated. RT-structure of contoured plate bolus in the TPS was exported to DICOM files and converted to STL file by using converting program. The 3D-printed bolus was manufactured with rubber-like translucent materials using a 3D printer. The dose distribution calculated in the TPS and compared the characteristics of the plate bolus and the 3D printed bolus. The absolute dose was measured inserting an ion chamber to the depth of 5 cm and 10 cm from the surface of the blue water phantom. HU and ED were measured to compare the material characteristics. 100% dose was distributed at Dmax of 1.5 cm below the surface when was applied without bolus. When the plate bolus and 3D-plate bolus were applied, dose distributed at 0.9 cm and 0.8 cm below the surface of the bolus. After the comparative analysis of the radiation dose at the reference depth, differences in radiation dose of 0.1 ~ 0.3% were found, but there was no difference dose. The usability of the 3D-printed bolus was thus confirmed and it is considered that the 3D-printed bolus can be applied in radiation therapy.

Keywords

References

  1. ICRU Report 62: Prescribing recording and reporting photon beam therapy (Supplement to ICRU report 50). Bethesda, MD: International Commission on Radiation Units and Measurement(ICRU).
  2. Bentel GC. Radiation therapy planning. 2nd ed. New York: McGraw‐Hill; 1996;239.
  3. Khan FM. The physics of radiation therapy. 3rd ed. Philadelpia: Lippincott Williams & Wilkins; 2014.
  4. Vyas V, Palmer L, Mudge R, et al. On bolus for megavoltage photon and electron radiation therapy. Medical Dosimetry. 2013;38(3):268-73. https://doi.org/10.1016/j.meddos.2013.02.007
  5. Kry SF, Smith SA, Weathers R, et al. Skin dose during radiotherapy: asummary and general estmation technigue. Journal of Applied Clinical Medical Physics. 2012;13(3):20-34. https://doi.org/10.1120/jacmp.v13i3.3734
  6. Butson MJ, Cheung T, Yu P, et al. Effects on skin dose from unwanted air gaps under bolus in photon beam radiotherapy. Radiation Measurements. 2000;32(3):201-4. https://doi.org/10.1016/S1350-4487(99)00276-0
  7. Khan Y, Villarreal-Barajas JE, Udowicz M, et al. Clinical and dosimetric implications of air gaps between bolus and skin surface during radiation therapy. Journal of Cancer Threrapy, 2013;4:1251-5. https://doi.org/10.4236/jct.2013.47147
  8. Benoit J, Pruitte AF, Thrall DE. Effect of wetness level on the suitability of wet gauze as a substitute for Superflab as a bolus material for use with 6MV photons. Veterinary Radiology & Ultrasound. 2009;50(5):555-9. https://doi.org/10.1111/j.1740-8261.2009.01573.x
  9. Morrison WH, Wong PF, Starkschall G, et al. Water bolus for electron irradiation of the ear canal. International Journal of Radiation Oncology Biology Physics. 1995;33(2):479-83. https://doi.org/10.1016/0360-3016(95)00023-R
  10. Nuclear Associates. Superflab(R) plastic bolus material. Fluke Biomedical. 2005;37‐07X‐1, Rev 2.
  11. Schubert C, van Langeveld MC, Donoso LA. Innoventions in 3D printing: a 3D overview from optics to organs. British Journal of Ophthalmology. 2014;98(2):159-61. https://doi.org/10.1136/bjophthalmol-2013-304446
  12. Shafiee A, Atala A. Printing technologies for medical applications. Trends in Molecular Medicine. 2016;22(3):254-65. https://doi.org/10.1016/j.molmed.2016.01.003
  13. Oh WK. Evaluation of usefulness and availability for Orthopedic Surgery using clavicle fracture model manufactured by Desktop 3D printer. Journal of Radiological Science and Technology. 2014;37(3):203-9
  14. Kudchadker RJ, Antolak JA, Morrison WH et al. Utilization of custom electron bolus in head and neck radiotherapy. Journal of Applied Clinical Medical Physics. 2003;4(4):321-33. https://doi.org/10.1120/jacmp.v4i4.2503
  15. Ju SG, Kim MK, Hong CS, Kim JS, Han Y, et al. New Technique for developing a proton range compansator with use of a 3-dimensional printer. International Journal of Radiation Oncology Biology Physics. 2014;88(2):453-8. https://doi.org/10.1016/j.ijrobp.2013.10.024
  16. Schubert C, van Langeveld MC, Donoso LA. Innovations in 3D printing. a 3D overview from optics to organs. Br J Ophthalmol. 2014;98:159-61. https://doi.org/10.1136/bjophthalmol-2013-304446
  17. Seong YH. Comparison of hounsfield Units by changing in size of physical area and setting size of region of interest by using the CT phatom made with 3D printer. Journal of Radiological Science and Technology. 2015;38(4):421-7. https://doi.org/10.17946/JRST.2015.38.4.12