한국전산구조공학회논문집 (Journal of the Computational Structural Engineering Institute of Korea)

  • 제33권3호
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  • Pages.179-186
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  • 2020
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  • 1229-3059(pISSN)
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  • 2287-2302(eISSN)
한국전산구조공학회 (Computational Structural Engineering Institute of Korea)
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복부대동맥류 형상 및 연령에 따른 동맥 벽 응력 특성 및 파열 위험성 평가

Evaluation of Stress Characteristics and Rupture Risk of the Aortic Wall According to Abdominal Aortic Aneurysm Geometry and Age

  • 이충원 (부산대학교병원 흉부외과) ;
  • 유지훈 (부산대학교 대학원 의공학전공) ;
  • 허업 (부산대학교병원 흉부외과) ;
  • 이치승 (부산대학교 의과대학 융합의학교실) ;
  • 유동만 (미시간주립대학교 기계공학과)
  • Lee, Chung Won (Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital) ;
  • You, Ji-Hun (Department of Biomedical Engineering, Graduate School, Pusan National Univ.) ;
  • Huh, Up (Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital) ;
  • Lee, Chi-Seung (Department of Convergence Medicine, School of Medicine, Pusan National Univ.) ;
  • Ryu, Dong-Man (Department of Mechanical Engineering, Michigan State Univ.)
  • 투고 : 2020.02.27
  • 심사 : 2020.03.26
  • 발행 : 2020.06.30
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초록

본 연구에서는 복부대동맥류가 발생한 환자들에서의 연령과 복부대동맥류 형상에 따른 벽 응력과 파열 위험성을 평가하였다. 복부대동맥류의 형상은 의료영상 데이터로부터 추출되어 모사되었으며, 재료 물성치 단계에서는 동맥 조직의 이방성 초탄성 성질을 모사하기 위해 Gasser-Ogden-Holzapfel 모델을 적용하였다. 또한, 모델에서 필요한 각 재료 정수들은 환자들의 연령과 정상 조직 및 동맥류 조직의 특성들을 고려하기 위하여 각기 다른 값들로 산정되었다. 게다가 복부대동맥류에서의 대동맥 직경과 목의 각도에 관한 상관관계를 분석하고, 이에 대한 시리즈 시뮬레이션 역시 수행되었다. 그 결과, 복부대동맥류 환자의 연령과 대동맥 직경, 그리고 대동맥 목의 각도에 따른 복부대동맥류의 파열 위험성이 평가되었다.

In this study, the wall stress and rupture risk for abdominal aortic aneurysms were calculated based on the age and geometry of the examined abdominal aortic aneurysms. The geometry of the abdominal aorta was simulated using computed tomography data from patients with abdominal aortic aneurysms. With regard to material properties, the Gasser-Ogden-Holzapfel model was applied to the analysis to simulate the anisotropic hyperelastic characteristics of the artery. In addition, each material parameter was estimated to consider the properties for age and for normal and aneurysm tissue. Moreover, the correlation between the diameter and angle of the aortic aneurysms was analyzed based on data from patients with abdominal aortic aneurysms, and series simulations were conducted. As a result, the rupture risk for the abdominal aortic aneurysms was evaluated based on the age and geometry of the aneurysm.

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참고문헌

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