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Analysis of the incidence of dementia in complete edentulous patients using the National Health Insurance Service-Elderly Cohort Database (NHIS-ECD)

국민건강보험공단 노인 코호트 자료를 이용한 완전 무치악 환자의 치매 발병률 분석

  • Koo, Bonsuk (Department of Prosthodontics, National Health Insurance Service Ilsan Hospital) ;
  • Yoo, Jin-Joo (Department of Prosthodontics, National Health Insurance Service Ilsan Hospital) ;
  • Kim, Manyong (Department of Prosthodontics, National Health Insurance Service Ilsan Hospital) ;
  • Lim, Hyunsun (Research and Analysis Team, National Health Insurance Service Ilsan Hospital) ;
  • Yoon, Joon-Ho (Department of Prosthodontics, National Health Insurance Service Ilsan Hospital)
  • 구본석 (국민건강보험 일산병원 치과보철과) ;
  • 유진주 (국민건강보험 일산병원 치과보철과) ;
  • 김만용 (국민건강보험 일산병원 치과보철과) ;
  • 임현선 (국민건강보험 일산병원 연구분석팀) ;
  • 윤준호 (국민건강보험 일산병원 치과보철과)
  • Received : 2020.03.24
  • Accepted : 2020.06.01
  • Published : 2020.07.31

Abstract

Purpose: To investigate the relationship between dementia and complete tooth loss on both sides or one side using large demographic data. Materials and methods: A retrospective cohort study was designed using the National Health Insurance Service-Elderly Cohort Database (NHIS-ECD) which was established for people over the age of 60. The experimental group was the complete edentulous cohort, which had a history of treatment for national health insurance covered complete denture on both sides or one side from July 1, 2012 to December 31, 2013. And the control group was the dentulous cohort, which had a history of conservative dental treatment for the same period. All subjects had no history of diagnosis or treatment of dementia during this time. These cohorts were matched 1:1 by age, gender, and place of residence according to the propensity score matching method. Then the incidence of dementia was compared between these cohorts. Results: Compared with those groups, the incidence of dementia was significantly higher in the experimental group (12.13%) than in the control group (9.74%) (P<.05). No clear association between other factors has been identified. Conclusion: The analysis of large-scale demographic data shows that the incidence of dementia is high in complete edentulous patients on both sides or one side.

목적: 대규모 인구집단데이터를 사용하여 양측 또는 편측 완전 무치악 여부와 치매와의 관련성에 대하여 알아본다. 재료 및 방법: 만 60세 이상을 대상으로 구축된 건강보험공단 노인 코호트 데이터베이스를 사용하여 후향적 코호트 연구를 설계하였다. 실험군은 완전 무치악 코호트로 2012년 7월 1일부터 2013년 12월 31일 까지 1개 이상의 상악 또는 하악 레진상 완전의치 보험 처방 이력이 있는 사람을 대상으로 하였고, 대조군은 유치악 코호트로 같은 기간 동안 잔존치아에 대한 보존적 치아 처치 이력이 있는 사람을 대상으로 하였다. 모든 대상자들은 이 기간 동안 치매로 진단 또는 치료 받은 기록이 없었다. 성향점수매칭법에 따라 연령과 성별, 그리고 거주지역을 고려하여 실험군과 대조군을 1:1 동수로 매칭하였고, 두 코호트 집단간 2년 동안 치매로 이환된 비율을 비교하였다. 결과: 실험군과 대조군을 비교했을 때, 실험군인 양측 또는 편측 완전 무치악 환자에서 치매 발병률(12.13%)은 대조군인 유치악 환자의 치매 발병률(9.74%) 보다 유의미하게 높다는 것을 확인할 수 있었다 (P < .05). 다른 요인들과 치매와의 명확한 관련성은 확인되지 않았다. 결론: 대규모 인구집단데이터 분석을 통해 양측 또는 편측 완전 무치악 환자에서 치매 발병률이 높다는 것을 확인할 수 있었다.

Keywords

References

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