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INSPIRE Neuro-Spinal Scaffold™ : An Implantable Alternative to Stem-Cell Therapy for Endogenous Repair in Spinal Cord Injury

  • Brown, Nolan (Department of Neurosurgery, University of California, Irvine School of Medicine)
  • Received : 2020.01.04
  • Accepted : 2020.02.14
  • Published : 2020.09.01

Abstract

Keywords

References

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  2. InVivo : Pipeline: Neuro-Spinal $Scaffold^{TM}$. Available at : https://www.invivotherapeutics.com/research-clinical-development/pipeline/neuro-spinal-scaffold/
  3. Jeong SK, Choi I, Jeon SR : Current status and future strategies to treat spinal cord injury with adult stem cells. J Korean Neurosurg Soc 63 : 153-162, 2020 https://doi.org/10.3340/jkns.2019.0146
  4. Teng YD, Lavik EB, Qu X, Park KI, Ourednik J, Zurakowski D, et al. : Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci U S A 99 : 3024-3029, 2002 https://doi.org/10.1073/pnas.052678899
  5. The National Spinal Cord Injury Statistical Center : Spinal Cord Injury Facts and Figures at a Glance. Available at : https://www.nscisc. uab.edu/PublicDocuments/fact_figures_docs/Facts%202013.pdf
  6. Theodore N, Hlubek R, Danielson J, Neff K, Vaickus L, Ulich TR, et al. : First human implantation of a bioresorbable polymer scaffold for acute traumatic spinal cord injury: a clinical pilot study for safety and feasibility. Neurosurgery 79 : E305-E312, 2016 https://doi.org/10.1227/neu.0000000000001283