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Ethnomedicinal Uses, Phytochemistry and Pharmacology of Dorema Species (Apiaceae): A Review

  • Zibaee, Elaheh (Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Amiri, Mohammad Sadegh (Department of Biology, Payame Noor University) ;
  • Boghrati, Zahra (Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Farhadi, Faeghe (Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Ramezani, Mahin (Nanotechnology Research Center, Mashhad University of Medical Sciences) ;
  • Emami, Seyed Ahmad (Department of Traditional Pharmacy, School of Pharmacy, Mashhad University of Medical Sciences) ;
  • Sahebkar, Amirhossein (Halal Research Center of IRI, FDA)
  • Received : 2018.03.25
  • Accepted : 2020.08.28
  • Published : 2020.09.30

Abstract

The application of antique medical instructions, practices, skills and knowledge has been considered as the most affordable treatment in many developing countries. The use of these preparations and prescriptions over generations has made a useful and valuable guide for drug discovery in modern medicine. Medical herbs have been of a high importance for this purpose. The genus Dorema, of Apiaceae family (Umbelliferae) has a wide use in ethnobotany and traditional medicine around the world. It has been used as a treatment for CNS disease, convulsion, upper respiratory tract problems, gastrointestinal disorder and high blood sugar. Furthermore, phytochemical investigations have reported Dorema species to contain a wide range of constituents including terpenes, coumarins and phenolic compounds. The current review summarizes comprehensive information regarding botany, phytochemistry and pharmacological aspects of Dorema spp.

Keywords

References

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