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문헌 고찰을 통해 본 영산재(靈山齋)에 등장한 여름 과실(果實)의 생리활성 효과 규명(I)

A Study on the Physiological Activities of Summer Fruits from Yeongsanjae Based on Review(I)

  • 김송희 (경기대학교 대학원 대체의학과) ;
  • 김애정 (경기대학교 대학원 대체의학과)
  • Kim, Song-Hee (Department of Alternative Medicine Graduate School Kyonggi University) ;
  • Kim, Ae-Jung (Department of Alternative Medicine Graduate School Kyonggi University)
  • 투고 : 2020.07.21
  • 심사 : 2020.09.04
  • 발행 : 2020.09.30

초록

본 연구는 우리나라 최고·최대의 불교의식인 영산재가 거행되는 여름철에 수확되는 포도, 수박, 참외, 용과의 공양물로서의 의의, 기능적 효과 및 생리활성에 대한 과학적 근거를 제시하고자 하였다. 영산재 및 2010년 3월부터 2020년 2월까지 발표 된 포도, 수박, 참외, 용과의 국내 연구를 중심으로 문헌고찰을 실시하였다. 고찰 결과, 영산재에서 과실은 육법공양(六法供養)의 하나로 귀의(歸依), 발원(發願), 축원(祝願)의 의미로 쓰이는 일종의 폐백(幣帛)이며 깨달음을 의미한다. 또한 불교수행자의 건강유지에 큰 역할을 했을 것으로 추정된다. 이러한 영산재 과실 공양물인 포도, 수박, 참외, 용과 모두 polyphenol, flavonoid와 같은 항산화 물질의 함량이 높았으며, DPPH 및 ABTS+ radical 소거능, 환원력 등의 항산화 활성, 면역증진, 항암, 혈관 확장 및 프리바이오틱스 관련 효과, 미백 및 주름개선 효과 등 항염증, 미생물 성장저해 등 항균효과가 뛰어났다. 이러한 생리활성 효과는 가식부위인 과육보다 비 가식부위인 과피에서 더 우수한 것으로 나타났다. 4과실 중 용과에 대한 연구는 매우 드문 실정으로 향후, 용과의 부위별 생리활성 연구와 4과실 과피의 식용 등 활용방안에 대한 연구가 더 이루어질 필요가 있다.

This paper presents the scientific basis for the significance and physiological activity of gongyang as tributes, focusing on the four summer fruits, i.e., grapes, watermelons, oriental melons, and dragon fruits, which were used as one of the yukbeopgongyang in Yeongsanjae's thorough literature review (yeongsanjae and 2010.3~2020.2 published fruit research). As a result of the study, the fruit is not obtained from fruit trees, but from enlightenment. Chemically, the fruit had a high content of antioxidants, such as polyphenol and flavonoid. The fruit had excellent DPPH and ABTS+ radical scavenging activities and reducing power. The skin of the fruits, the non-edible part, had higher physiological activity than the flesh, the edible part. Therefore, further studies on the physiological activity in each part of dragon fruit and regarding how to ingest and utilize the peel of the four fruits need to be conducted.

키워드

참고문헌

  1. Pup Hyon, A study of Youngsanjae, p.15, Unjusa, 1997.
  2. J.B. Choi, A study on the Kwanyinsisik of Yeongsanjae, Master's thesis, Dongguk University, Seoul, Korea, pp. 36-43, 2012.
  3. M.H. Kang, A study on the 'Shikdang-Jakbeob' of Youngsanjae: focusing on 'Gongyang and Ban Seung', Ph.D dissertation, Wonkwng University, Iksan, Korea, pp. 11-14, pp. 38, pp. 73, 2019.
  4. Y.S. Hong, Yeongsanjae, pp. 8-17, Daewonsa, 2001.
  5. Pup Hyon, Buddhist music in Korea, pp. 16, Unjusa, 2005.
  6. S.H. Shim, Important intangible cultural properties 50 Yeongsanjae, pp. 8-12, pp,132, pp,354, ymbook, 2003.
  7. S.H. Ko, "Study on the origin and development of Yeongsanjae", Korean Journal of Cultural Heritage Studies, Vol. 49, No. 4, pp. 180-195, Dec. 2016. DOI: https://doi.org/10.22755/kjchs.2016.49.4.180
  8. M.S. Kong, "A Study of the relations between food and meditation in the early buddhism", Studies of Seon Culture, Vol. 4, pp. 1-35, Jun. 2008.
  9. Jogye Order of Korean Buddhism, Buddhist ritual Guide, p.43, Jogyebook, 2010.
  10. G.H. Cha, Y.J. Song, "The Kimi theory on fruits [Tangaekpyeon] in Donguibogam and [Sikgamchalyo] of [Jeongjoji] in Limwonsibyukji,", Korean Journal of Food and Cookery Science, Vol. 22, No. 6, pp. 930-939, Dec. 2016.
  11. J. Sun, Y.F. Chu, X. Wu, R.H. Liu, "Antioxidant and antiproliferative activities of common fruits", Journal of Agriculture and Food Chemistry, Vol. 50, pp. 7449-7454, Nov. 2002. DOI: https://doi.org/10.1021/jf0207530
  12. J. Kubola, S. Siriamornpun, "Phytochemicals and antioxidant activity of different fruit fractions(peel, pulp, aril, and seed) of Thai gac(Momordica cochinchinensis Spreng)", Food Chemistry, Vol. 127, No. 3, pp. 1138-1145, Aug. 2011. DOI: https://doi.org/10.1016/j.foodchem.2011.01.115
  13. M.Y. Lee, M.S. Yoo, Y.J. Whang, Y.J. Jin, M.H. Hong, Y.H. Pyo, "Vitamin C, total polyphenol, flavonoid contents and antioxidant capacity of several fruit peels", Korean Society of Food Science and Technology, Vol. 44, No. 5, pp. 540-544, Oct. 2012. DOI: https://doi.org/10.9721/KJFST.2012.44.5.540
  14. J.R. Lee, "Analysis of the meaning of four types of offerings in Samantapasadika", Bul Gyo Hak Bo 75, pp. 83-102, Jun. 2016. DOI: https://doi.org/10.18587/bh.2016.06.75.83
  15. H.J. Lee, Korean food culture, pp38-39, Shinkwangpub, 1998.
  16. G.H. Cha, Y.J. Song, H.G. Lee, "The Kimi theory on [Jeongjoji] [Tangaekpyeon] in Donguibogam-", Korean Journal of Food and Cookery Science, Vol. 22, No. 5, pp. 690-701, Oct. 2006.
  17. H.S. Kim, M.J. Hong, I.Y. Kang, J.Y. Jung, H.K. Kim, Y.S. Shin, H.J. Jun, J.K. Suh, Y.H. Kang, "Radical scavenging activities antioxidant constituents of oriental melon extract", Journal of Bio-environment Control, Vol. 18, No. 4, pp. 442-447, Dec. 2009.
  18. S.W. Chang, H.J. Kim, J.H. Song, K.Y. Lee, I.H. Kim, Y.T. Rho, "Determination of several phenolic compounds in cultivars of grape in Korea", Korean Journal of Food Preservation, Vol. 18, No. 3, pp. 328-334, Jun. 2011. DOI: https://doi.org/10.11002/kjfp.2011.18.3.328
  19. C.H. Cho, S.Y. Kim, G.J. Yoo, M.H. Son, K.H. Park, B.L. Lim, D.C. Kim, H.J. Chae, "Resveratrol extraction from grape fruit stem and its antioxidant activity", Journal of Korean Society for Applied Biological Chemistry, Vol. 51, No. 1, pp. 11-16, Mar. 2008.
  20. C.C. Neto, "Cranberry and blueberry: evidence for protective effects against cancer and vascular diseases", Molecular Nutrition & Food Research, Vol. 51, pp. 652-664, May. 2007. DOI: https://doi.org/10.1002/mnfr.200600279
  21. S.K. Hur, S.S. Kim, Y.H. Heo, S.M. Ahn, B.G. Lee, S.K. Lee, "Effects of the grapevine shoot extract on free radical scavenging activity and inhibition of pro-inflammatory mediator production in RAW264.7 macrophages", Biomolecules & Therapeutics, Vol. 9, No. 3, pp. 188-193, Sep. 2001.
  22. S.J. Park, H.Y. Lee, D.H. Oh, "Free radical scavenging effect of seed and skin extracts from campbell early grape(Vitis labruscana B.)", Journal of the Korean Society of Food Science and Nutrition, Vol. 32, No. 10, pp. 115-118, Feb. 2003. DOI: http://dx.doi.org/10.3746/jkfn.2003.32.1.115
  23. S.M. Jeong, S.Y. Kim, J.U. Ha, S.C. Lee, "Effect of far-infrared irradiation on the antioxidant activity of extracts from grape seed", Journal of the Korean Society of Food Science and Nutrition, Vol. 34, No. 10, pp. 1619-1624, Dec. 2005. DOI: http://dx.doi.org/10.3746/jkfn.2005.34.10.1619
  24. K.H. Seo, S.Y. Yu, H.W. Kwak, "Cytoprotective effect of polyphenolic compounds against oxidative stress in cultured retinal pigment epithelial cells", Journal of The Korean Ophthalmological Society, Vol. 57, No. 1, pp. 106-112, Jan. 2016. DOI: http://dx.doi.org/10.3341/jkos.2016.57.1.106
  25. H. Quesada, J.M. Del Bas, D. Pajuelo, S. Diaz, J. Femandez-Larrea, M. Pinent, L. Arola, M.J. Salvado, C. Blade, "Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver", International Journal of Obesity, Vol. 33, No. 9, pp. 1007-1012, Jul. 2009. DOI: https://doi.org/10.1038/ijo.2009.136
  26. E.H. Chang, S.M. Jung, B.S. Lim, J.H. Noh, K.S. Park, H.S. Hwang, "Determination of phenolic compounds and trans-resveratrol in different parts of Korea new grape cultivars", Korean Society For Horticultural Science, Seoul, Korea, Vol. 30, pp. 53-54, 2012.
  27. Y.N. Kim, Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis, Ph.D dissertation, Konyang University, Nonsan, Korea, pp. 59-83, 2017.
  28. B.Y. Lee, D.H. Jee, "Association between grapes intake and diabetic retinopathy: Inhibitory effect of resveratol on diabetic retinopathy", Journal of the Korean Ophthalmological Society, Vol. 57, No. 2, pp. 276-282, Feb. 2016. DOI: https://doi.org/10.3341/jkos.2016.57.2.276
  29. M.K. Park, J.H. Oh, "Antioxidant and antimicrobial activities of muscadine grape extracts", Korean Journal of Food Preservation, Vol. 22, No. 1, pp. 12-18, Jan. 2015. DOI: http://dx.doi.org/10.11002/kjfp.2015.22.1.12
  30. J.Y. Baek, Chemical components and biological activities of wine by-product, Master's thesis, Korea Maritime and Ocean University, Busan, Korea, pp. 30-95, 2017.
  31. J.I. Chu, Studies on the biological activities of Pleurotus eryngii and grape branch extract, Ph.D dissertation, Jeonju University, Jeonju, Korea, pp. 40-48, pp. 88-94, 2018.
  32. Y.S. Kim, J.W. Hwang, W.B. Shin, J.S. Park, S.J. Park, P.J Park, "Antioxidant activity and protective effect of extracts from Vitis vinifera root on t-BHP induced oxidative stress in Chang cells", Journal of the Korean Society of Food Science and Nutrition, Vol. 47, No. 2, pp. 136-142, Feb. 2018. DOI: http://dx.doi.org/10.3746/jkfn.2018.47.2.136
  33. M.C. Lazze, R. Pizzala, F.J.G. Pecharroman, P.G. Garnica, J.M.A. Rodriguez, N. Fabris, L. Bianchi, "Grape waste extract obtained by supercritical fluid extraction containes bioactive antioxidant molecules and induces antiproliferative effects in human colon adenocarcinoma cells", Journal of Medicinal Food, Vol. 12, pp. 561-568, Jul. 2009. DOI: https://doi.org/10.1089/jmf.2008.0150
  34. S.A. Park, Effects of single ingestion of polyphenol extract from grape seed on normotensive men's vascular endothelial function and cardiovascular response during dynamic exercise, Master's thesis, Kyung-Hee University, Seoul, Korea, pp. 57-64, 2016.
  35. K.A. Kim, DS. Lee, J.Y. Kim, "Effect of supplementation with polyphenol extract from grape seed on blood lipid levels in postmenopausal women: A pilot study", Korean Society for Wellness, Vol. 12, No. 1, pp. 529-534, Feb. 2017. DOI: http://dx.doi.org/10.21097/ksw.2017.02.12.1.529
  36. E. Park, I. Edirisinghe, Y.Y. Choy, A. Waterhouse, B.B. Freeman, "Effect of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial", British Journal of Nutrition, Vol. 115, No. 2, pp. 226-238, Jan. 2016. DOI: http://dx.doi.org/10.1017/S0007114515004328
  37. S.M. Joen, K.A. Kim, M.G. Lee, "Effect of grape seed extract on cardiovascular response and vascular endothelial cell function in the prehypertensive individuals", The Korea Journal of Sports Science, Vol. 27, No. 2, pp. 1027-1039, Apr. 2018. DOI: http://dx.doi.org/10.35159/kjss.2018.04.27.2.1027
  38. J.H. Park, M.H. Um, S.Y. Ju, Y.K. Park, "Effect of 12 weeks supplementation of grape seed extract complex on improving menopausal symptoms of postmenopausal women: A randomized placebo-controlled trial", Journal of the Korean Society of Food Science and Nutrition, Vol. 48, No. 8, pp. 922-932, Sep. 2019. DOI: http://dx.doi.org/10.3746/jkfn.2019.48.9.922
  39. M.A. Park, K.J. Kang, "Effect of grape skin extract on apoptosis in MDA-MB-231 human breast cancer cells", Journal of the East Asian Society of Dietary Life, Vol. 25, No. 1, pp. 87-98, Feb. 2015. DOI: http://dx.doi.org/10.17495/easdl.2015.2.25.1.87
  40. K.D. Kang, J.G. Jeung, R. Afzal, H.P. Yang, H.B. Hwang, "Effect of grape skin extract, anthocyanin oligomer, on a murine dry model", Journal of the Korean Society of Food Science and Nutrition, Vol. 48, No. 4, pp. 395-402, Apr. 2019. DOI: http://dx.doi.org/10.3746/jkfn.2019.48.4.395
  41. D.W. Park, Evaluation biological activities of Grape(Vitis labrusca L.) Pruning stems extract and establishing stability of sunscreen that contain it, Master's thesis, Yeungnam University, Gyeongsan, Korea, pp. 20-43, 2017.
  42. J.H. Kim, D.H. Kim, K.J. Kim, "Grape pruning stem extract(GPSE) suppresses allergy and skin proliferation inhibition against UVB induced skin damage" Korean Journal of clinical Laboratory Science, Vol. 49, No4, pp. 329-336, Dec. 2017 DOI: https://doi.org/10.152324/kjcls.2017.49.4.329K.S
  43. K.S. Youn, "Comparison of the antioxidant effects and physiological activities of grape fruit stem extracts derived with different drying method", Korean Journal of Food Preservation, Vol. 25, No. 3, pp. 382-389, Apr. 2018. DOI: http://dx.doi.org/10.11002/kjfp.2018.25.3.382
  44. H.J. Han, Effect of combined grape pomace and omija ethanol extracts on plasma lipid profiles, inflammation and antioxidant capacity in subjects with overweight or obesity, Master's thesis, Kyungpook National University, Daegu, Korea, pp. 63-66, 2015.
  45. M.A. Park, K.J. Kang, "Effect of grape skin extract on apoptosis in MDA-MB-231 human breast cancer cells". Journal of the East Asian Society of Dietary Life, Vol. 25, No. 1, pp. 87-98, 2015. DOI: http://dx.doi.org/10.17495/easdl.2015.2.25.1.87
  46. T.S. Hudson, D.K. Hartle, S.D. Hursting, N.P. Nunez, T.T. Wang, H.A. Young, P. Arany, J.E. Green, "Inhibition of prostate cancer growth by muscadine grape skin extract and resveratrol through distinct mechanisms", Cancer Resarch, Vol. 67, pp. 8396-8405, Sep. 2007. DOI: https://doi.org/10.1158/0008-5472.CAN-06-4069
  47. D.M. Morre, D.J. Morre, "Anticancer activity of grape and grape skin extracts alone and combined with green tea infusions", Cancer letters, Vol. 238, pp. 202-209. Jul. 2006. DOI: https://doi.org/10.1016/j.canlet.2005.07.011
  48. S.P. Hong, J.Y.L Lim, E.J. Jeong, D.H. Shin, "Physicochemical properties of watermelon according to cultivars", Korean Journal of Food Preservation, Vol. 15, No. 5, pp. 706-710, Oct. 2008.
  49. J.S. Sohn, S.H. Kim, "Effects of hesperidin and naringin on antioxidative capacity in the rat", The Korean Journal of Nutrition., Vol. 31, No. 4, pp. 687-696, May. 1998.
  50. T.G. Jeong, S.Y. Nam, J.W. Han, T.I. Kim, Y.S. Kim, H.J. Kang, S.B. Lee, M.H. Kim, T.J. Kim, "Study on the analysis of the active ingredient fruit unripe watermelon(Citrullus Ianatus Thunb.)", The Plant Resources Society of Korea, Seoul, Korea. pp. 81-81, Sep. 2014.
  51. W.M. Lee, H.J. Lee, E.Y. Yang, H.S. Chi, S. Kim, S.Y. Chae, Y.C. Huh, D.K. Park, "Screening of germplasms with high lycopene content in watermelon(Citrullus lanatus (Thunb.) Matsum. & Nakai)", Korean Society For Horticultural Science, Wanju, Korea, Vol. 31, pp. 83-83, May. 2013.
  52. T.S. Park, J.H. Moon, E.Y. Yang, Y.C. Huh, O.R. Kim, M.Y. Roh, S.G. Kim, S.Y. Chae, W.J Park, "Analysis of quantitative trait locus for lycopene and citrulline in watermelon", Korean Society for Horticultural Science, Wanju, Korea, Vol. 35, pp. 113-142, Oct. 2017.
  53. Y. Duan, Kim MA, Kim HS, Jang SH, Kang DS. "Screening of antioxidant activity from exocarp of watermelon(Citrullus vulgaris L.)", Journal of Environmental Science International, Vol. 23, No. 7, pp. 1233-1239, Apr. 2014. DOI: https://doi.org/10.5322/JESI.2014.23.7.1233
  54. J.Y. Baek, S.Y. Lim, "Flavonoid and phenol contents and antioxidant effect of wine by-product extracts", Journal of Life Science, Vol. 26, No. 8, pp. 948-954, Aug. 2016. DOI: https://doi.org/10.5352/JLS.2016.26.8.948
  55. H.I. Jeon, G.S. Song, Y.S. Kim, "Physicochemical properties of alcohol insoluble polysaccharides fractions from watermelon and oriental melon peels and their effects on growth of intestinal bacteria", Journal of the Korean Society of Food Science and Nutrition, Vol. 47, No. 10, pp. 981-987, Oct. 2018. DOI: http://dx.doi.org/10.3746/jkfn.2018.47.10.981
  56. T.C. Jeong, J.W. Han, T.L. Kim, Y.S. Kim, S.J. Noh, I.J. Kim, "Analysis on the content of lycopene and sugar component each mini watermelon varieties", Korean Society for Horticultural Science, Wanju, Korea, Vol. 34, pp. 126-126, May. 2016.
  57. J.Y. Choi, Lycopene inhibits house dust mites-induced TLA4 activation and oxidative stress in respiratory epithelial cells, Master's Thesis, Yonsei University, Seoul, Korea, pp. 20-23, pp. 29-31, 2015.
  58. W.M. Lee, H.J. Lee, E.Y. Yang, H.S. Chi, S. Kim, M.J. Kwon, S.Y. Chae, Y.C. Huh, D.K. Park, "Screening of germplasms with high Citrulline content in watermelon(Citrullus lanatus (Thunb. ) Matsum. & Nakai)", Korean Society For Horticultural Science, Wanju, Korea, Vol. 31, pp. 95-95, Oct. 2013.
  59. D.J. Heo, S.J. Kim, A.R. Choi, H.R. Park, S.C. Lee, "Tyrosinase inhibitory activity and neuronal cell protection of hydrothermal extracts form watermelons", Journal of the Korean Society of Food Science and Nutrition, Vol. 42, No. 10, pp. 1707-1711, Oct. 2013. DOI: http://dx.doi.org/10.3746/jkfn.2013.42.10.1707
  60. A.L. Jeon Identification of anti-inflammatory, anti-bacterial and skin whitening constituents from the aerial parts of Citrullus lanatus. Master's thesis, Jeju National University, Jeju, Korea, pp. 34-53, 2016.
  61. A.L. Jeon, J.E. Kim, N.H. Lee, "Whitening and anti-inflammatory constituents from the extract of Citrullus Ianatus v ines", Journal of the Society of Cosmetic Scientists of Korea, Vol. 43, No. 1, pp. 53-60, Mar. 2017. DOI: https://doi.org/10.15230/SCSK.2017.43.1.53
  62. Y.S. Shin, J.E. Lee, I.K. Yeon, H.W. Do, J.D. Cheung, C.K. Kang, S.Y. Choi, S.J. Youn, J.G. Cho, D.J. Kwoen, "Antioxidant effects and tyrosinase inhibition activity of oriental melon(Cucumis melo L. var. makuwa Makino) extracts", Journal of Life Science, Vol. 18, No. 7, pp. 963-967, Jul. 2008. DOI: https://doi.org/10.5352/JLS.2008.18.7.963
  63. I.J. Kang, N.Y. Ha, Y.J. Choi, "Functional properties og Muskmelon vinegars manufactured with traditional fermentation method", Journal of Life Scienc, Vol. 29, No. 3, pp345-353, November 2019. DOI: https://doi.org/10.5352/JLS.2019.29.3.345
  64. H.S. Kim, Y.H. Kang, "Antioxidant activity of extracts of non-edible parts(stalk, stem.leaf, seed) from oriental melon", Korean Journal of Plant Resources, Vol. 23, No. 5, pp. 451-457, Oct. 2010.
  65. Y.K. Cho, The functional character and effects of BangUL(Mini) oriental melon, Ph.D dissertation, Kongju National University, Kongju, Korea, pp. 29-61, 2016.
  66. H.S. Kim, Chemopreventive activity and functional constituents of oriental melon extract, Master's thesis, Kyungpook National University, Daegu, Korea, pp. 11-33, 2010.
  67. H.S. Kim, Y.H. Kang, "Effect of harvest time on antioxidant activity and functional constituents of oriental melons", Current Research on Agriculture and Life Sciences, Vol. 31, No. 3, pp. 209-216, Sep. 2013.
  68. K.I. Jung, N.Y. Ha, Y.J. Choi, "Functional properties of muskmelon vinegars with traditional fermentation methods", Journal of Life Science, Vol. 29, No. 3, pp. 345-353, Mar. 2019. DOI: https://doi.org/10.5352/JLS.2019.29.3.345
  69. National Institute of Horticultural and Herbal Science, Cultivation and pests management manual of dragon fruit, p4. Rural Development Administration, 2012.
  70. M.S. Kang, H.K. Han, Y.H. Lee, J.B. Kim, Y.S. Cho, J.H. Kim, H.J. Park, S.Y. Kim, "Nutrient analysis in pitaya fruit(Hylocereus sp.) from various cultivars", Journal of the Korean Society of Food Science and Nutrition, pp. 246-247, Oct. 2010.
  71. Y.R. Rodriguez, "The effect of administrating an extract from pitaya juice rich in betalains on cisplatin induced nephrotoxicity and cellular damage, in vivo and vitro", Free Radical Biology & Medicine, Vol. 128, No. 1, pp. 98-98, Nov. 2018. DOI: https://doi.org/10.1016/j.freeradbiomed.2018.10.232
  72. X.L. Bia, H.W. Zang, "P41 Microwave-assisted extraction and HPLC analysis of polyphenols from pitaya peel and its inhibitory effect on human lung cancer cell line A549", Biochemocal pharmacoiogy, Vol. 139, pp. 139-140, Sep. 2017. DOI: https://doi.org/10.1016/j.bcp.2017.06.042
  73. T.C. Chemah, A. Aminah, W.M. Wan Aida. "Determination of pitaya seeds as a natural antioxidant and source of essential fatty acids", International Food Research Journal, Vol. 17, pp. 1003-1010, Nov. 2010.
  74. H.J. Chung, "Comparative study of antioxidant activity of imported tropical and subtropical fruits", Korean Journal of Food Preservation, Vol. 22, No. 4, pp. 577-584, Aug. 2015. DOI: http://dx.doi.org/10.11002/kjfp.2015.22.4.577
  75. S.A. Zulkifli, S.S.A. Gani, U.H. Zaidan, M.I.E. Halmi "Optimization of total phenolic and flavonoid contents of defatted pitaya(Hylocereus polyrhizus) seed extract and its antioxidant properties", Molecules a Journal of Synthetic Chemistry and Natura Product Chemistry, Vol. 25, No. 4, pp. 787, Feb. 2020. DOI: https://doi.org/10.3390/molecules25040787
  76. L.C. Wu, H.W. Hsu, Y.C. Chen, C.C. Chiu, Y.I. Lin, J.A. Ho, Antioxidant and antiproliferative activities of red pitaya, Food chemistry, Vol. 95, No. 2, pp319-327, 2006. https://doi.org/10.1016/j.foodchem.2005.01.002
  77. K.X. Wolfe, X. Wu, R.H. Liu, "Antioxidant activity of apple peels", Journal of Agricultural and Food Chemistry, Vol. 51, No. 3, pp. 609-614, Jan. 2003. DOI: https://doi.org/10.1021/jf020782a
  78. M. Brosche, A. Strid, "Molecular events following perception of ultraviolet-B radiation by plants", Physiologia Plantarum, Vol. 117, pp. 1-10, Dec. 2002. DOI: https://doi.org/10.1034/j.1399-3054.2003.1170101.x
  79. I.C.W. Arts, P.C.H. Hollman, "Polyphenols and disease risk in epidemiologic studies", The American Journal of Clinical Nutrition, Vol. 81, No. 1, pp. 317-325, Jan. 2005. DOI: https://doi.org/10.1093/ajcn/81.1.317S
  80. B.A. Graf, P.E. Milbury, J.B. Blumberg, "Flavonols, flavonones, flavanones and humam health: epidemological evidence", Journal of Medicinal Food, Vol. 8, No. 3, pp. 281-290, Sep. 2005. DOI: https://doi.org/10.1089/jmf.2005.8.281
  81. H.Y. Lee, H.S. Lee, "The roles of dietary polyphenols in brain neuromodulation", Journal of Life Science, Vol. 28, No. 11, pp. 1386-1395, Nov. 2018. DOI: https://doi.org/10.5352/JLS.2018.28.11.1386