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기능성소화불량에 대한 담음 변증설문지 개발과 신뢰도 및 타당도 검정

Development of a Phlegm Pattern Questionnaire for Functional Dyspepsia and Analysis of Its Reliability and Validity

  • 백소영 (경희대학교 대학원 임상한의학과) ;
  • 하나연 (경희대학교 대학원 임상한의학과) ;
  • 고석재 (경희대학교 대학원 임상한의학과) ;
  • 박재우 (경희대학교 대학원 임상한의학과) ;
  • 김진성 (경희대학교 대학원 임상한의학과)
  • Baek, So-young (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Ha, Na-yeon (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Ko, Seok-jae (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Park, Jae-woo (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University) ;
  • Kim, Jin-sung (Dept. of Clinical Korean Medicine, Graduate School, Kyung Hee University)
  • 투고 : 2020.08.03
  • 심사 : 2020.10.13
  • 발행 : 2020.09.30

초록

Objectives: The aim of this study was to develop a Phlegm Pattern Questionnaire for Functional Dyspepsia (PPQ-FD) by modifying a previously developed Phlegm Pattern Questionnaire (PPQ) and to verify its reliability and validity. Further objectives were to obtain the optimal cut-off value for the PPQ-FD for standardization and for clinical use. Methods: The PPQ-FD was developed by extracting the major symptoms of the phlegm pattern in functional dyspepsia and by using the Delphi method to administer a requested importance survey to experts. The reliability, validity, and optimal cut-off value of the PPQ-FD were analyzed by enrolling a total of 60 subjects in this study. Thirty patients were diagnosed with both functional dyspepsia and phlegm pattern and thirty patients were diagnosed with only functional dyspepsia. All participants were requested to fill out the PPQ-FD. Results: No statistically significant differences were detected in the two groups for sex distribution, age, or body mass index. Five of the survey questions negatively affected its reliability; therefore, we decided to exclude those five questions on further inspection. The Cronbach's α coefficient of the revised PPQ-FD was 0.853, and clinical validity was verified. Construct validity was analyzed by factor analysis and identified four factors. Statistically significant positive correlations were found between the revised PPQ-FD and other dyspepsia scales, such as the SQDQ, SSQD, VAS, NDI-K, and FD-QoL scales. The VAS had particularly strong positive correlations with the PPQ-FD. Conclusions: The PPQ-FD developed in this study has fundamental reliability and validity for use as a pattern-diagnosis questionnaire. The PPQ-FD can help to diagnose the phlegm pattern in patients with functional dyspepsia.

키워드

참고문헌

  1. Oh JH, Kwon JG. Functional dyspepsia. Korean J Gastroenterol 2019;73(2):77-83. https://doi.org/10.4166/kjg.2019.73.2.77
  2. Committee of Digestive Diesease, National Korean Medicine College. Gastroenterology. Seoul: Koonja; 2008, p. 348.
  3. Chang IK, Park DW, Ryu BH, Lee IS. Result of researching cause of disease, condition of an illness treatment about phlegm retention disease. J Korean Med 1986;7(1):160-9.
  4. Park JS, Yang DH, Kim MY, Lee SC, Park YJ. Development of Questionnire for Damum Patternization. J Korea Instit Orient Med Diagn 2006;10(1):64-77.
  5. Kim H. Development of International Versions of Pattern Identification Questionnaires using Cross-cultural Translation Methodology:Seven Emotions, Fatigue and Malaise, Phelgm, Food Retension, and Blood Stasis. J Korea Instit Orient Med Diagn 2018;22(1):33-44.
  6. Kim SK, Park YB. Development of Questionnaire for Cold-Heat Patternization. J Korea Instit Orient Med Diagn 2003;7(1):64-75.
  7. Lee BH, Kim MY, Park YB, Park YJ. Development of a valid and reliable seven emotions impairment questionnaire and assessment of its predictability for phlegm and blood stasis. J Tradit Chin Med 2016;36(4):547-54. https://doi.org/10.1016/S0254-6272(16)30073-5
  8. Yoon KJ, Park YB, Park YJ, Kim MY. Development and Validation of A Lao Juan Questionnaire. Chin J Integr Med 2015;21(7):500-6. https://doi.org/10.1007/s11655-015-2079-4
  9. Park YJ, Cho SW, Lee BH, Park YB. Development and Validation of the Yin Deficiency Scale. J Altern Complement Med 2013;19(1):50-6. https://doi.org/10.1089/acm.2011.0677
  10. Park YJ, Yang DH, Lee JM, Park YB. Development of a valid and reliable blood stasis questionnaire and its relationship to heart rate variability. Complement Ther Med 2013;21(6):633-40. https://doi.org/10.1016/j.ctim.2013.08.019
  11. Park JS, Yang DH, Kim MY, Lee SC, Park YJ. Development of Questionnaire for Damum Patternization. J Korea Instit Orient Med Diagn 2006;10(1):64-77.
  12. Park YJ, Lim JS, Park YB. Development of a valid and reliable food retention questionnaire. Eur J Integr Med 2013;5(5):432-7. https://doi.org/10.1016/j.eujim.2013.06.002
  13. Oh HW, Lee JW, Kim JS, Song EY, Shin SW, Han GJ, et al. Study on the Development of a Standard Instrument of Diagnosis and Assessment for Spleen Qi Deficiency Pattern. J Korean Med 2014;35(1):157-70. https://doi.org/10.13048/jkm.14015
  14. Lee JH, Park JW, Ko SJ, Kim JS. Development and validation of a new pattern identification scale for Stomach Qi Deficiency. Eur J Integr Med 2018;17:56-63. https://doi.org/10.1016/j.eujim.2017.11.009
  15. Han G, Kim J, Park JW, Ryu B. Pattern Identification of 97 Functional Dyspepsia Patients and the Characteristics of Each Pattern Type. J Korean Oriental Med 2011;32(2):42-62.
  16. Park YJ, Park JS, Kim MY, Park YB. Development of a Valid and Reliable Phlegm Pattern Questionnaire. J Altern Complement Med 2011;17(9):851-8. https://doi.org/10.1089/acm.2010.0504
  17. Kim JH, Kim JY, Kim JS, Kim KH. Reliability and Validity Analysis of a Standard Instrument of Diagnosis and Assessment for Spleen Qi Deficiency Pattern in Chronic Dyspepsia Patients. J Korean Med 2015;36(3):23-34. https://doi.org/10.13048/jkm.15017
  18. Talley NJ, Haque M, Wyeth JW, Stace NH, Tytgat GN, Stanghellini V, et al. Development of a new dyspepsia impact scale: the Nepean Dyspepsia Index. Aliment Pharmacol Ther 1999;13(2):225-35. https://doi.org/10.1046/j.1365-2036.1999.00445.x
  19. Lee SY, Choi SC, Cho YK, Choi MG. Validation of the Nepean Dyspepsia Index-Korean version. Kor J Neurogastroenterol Mot 2003;9(suppl):48S.
  20. Lee EH, Hahm KB, Lee JH, Park JJ, Lee DH, Kim SK, et al. Development and validation of a Functional Dyspepsia-Related Quality of Life (FD-QOL) scale in South Korea. J Gastroenterol Hepatol 2004;21(1):268-74. https://doi.org/10.1111/j.1440-1746.2006.04196.x
  21. Cremonini F, Talley NJ. Review article: the overlap between functional dyspepsia and irritable bowel syndrome - a tale of one or two disorders? Alment Pharmacol Ther 2004;20(7):40-9. https://doi.org/10.1111/j.1365-2036.2004.02184.x
  22. Quigley EMM, Lacy BE. Overlap of functional dyspepsia and GERD-diagnostic and treatment implications. Nature Reviews. Gastroenterology & Hepatology 2013;10(3):175-86.
  23. Chang L. The association of functional gastrointestinal disorders and fibromyalgia. Eur J Surg 1998;583:32-36. https://doi.org/10.1080/11024159850191210
  24. Malt EA, Berle JE, Olafsson S, Lund A, Ursin H. Fibromyalgia is associated with panic disorder and functional dyspepsia with mood disorders: A study of women with random sample population controls. J Psychosom Res 2000;49(5):285-9. https://doi.org/10.1016/S0022-3999(00)00139-2
  25. World Health Organiztion. Western Pacific Region. WHO international Standard Terminologies on Traditional Medicine in the Western Pacific region. 13. 2007.
  26. Smith F. Research Methods in Pharmacy Practice. London: Pharmaceutical Press; 2002, p. 43-84.
  27. Knapp TR. Coefficient alpha: Conceptualizations and anomalies. Research In Nursing & Health 1990;14(6):457-80. https://doi.org/10.1002/nur.4770140610
  28. Hylley SB, Cummings SR, Browner WS, Grady DG, Newman TB. Designing Clinical Research 4th edition. Philadelphia: Lippincott Williams & Wilkins; 2013, p. 47-8.
  29. Muller MP, Tomlinson G, Marrie TJ, Tang P, McGeer A, Low DE, et al. Can Routine laboratory tests discriminate between severe acute respiratory syndrome and other causes of community-acquired pneumonia? Clin Infect Dis 2005;40(8):1079-86. https://doi.org/10.1086/428577

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