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Study on the Correlation between Dietary Vitamin B Intakes and Clinical Indices of Type 2 Diabetes Patients

제2형 당뇨병 환자의 비타민 B 섭취와 임상지표의 상관관계에 대한 연구

  • Shim, Eugene (Department of Food and Nutrition, Soongeui Women's College) ;
  • Kwon, Ji-young (Graduate School of Human Environmental Sciences, Yonsei University) ;
  • Chung, Hae-Yun (Department of Food and Nutrition, Soongeui Women's College)
  • 심유진 (숭의여자대학교 식품영양과) ;
  • 권지영 (연세대학교 생활환경대학원) ;
  • 정혜연 (숭의여자대학교 식품영양과)
  • Received : 2020.10.05
  • Accepted : 2020.10.28
  • Published : 2020.10.31

Abstract

The objective of this study was to investigate the effects of dietary vitamin B intake on biomarkers related to lipid metabolism, inflammation and blood glucose control, that are important in the development of type 2 diabetes and its complications. Seventy-six adults (42 males, 34 females) were recruited from a group of diabetes patients who had visited the medical center for treatment. Data on anthropometric characteristics and dietary intake of thiamine, riboflavin, niacin, vitamin B6 and folate were collected using 24-hour diet recall and the CAN Pro 4.0 program. Also, data on clinical indices such as serum lipids, blood pressure, high-sensitivity C-reactive protein (hs-CRP), hemoglobin A1c (HbA1c) and homeostasis model assessment 2-insulin resistance (HOMA2-IR) were collected and analyzed for correlation with dietary vitamin B intake. Results from the dietary intake survey showed that riboflavin and folate intake (in males) and folate intake (in females) were below the Dietary Reference Intake for Koreans. Statistical analysis revealed a negative correlation between hs-CRP and dietary intake of B vitamins. Riboflavin intake was inversely associated with systolic blood pressure after adjustments for age, BMI, smoking, alcohol consumption, exercise, ingestion of diabetes mellitus medication and energy intake (p<0.05). Our results suggest that dietary vitamin B may influence inflammation and consequently may help in better management of type 2 diabetes.

Keywords

References

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