The Journal of the Convergence on Culture Technology (문화기술의 융합)

The International Promotion Agency of Culture Technology (국제문화기술진흥원)
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A Case-Control Study on Attitudes to Dietary Life and Nutrient Intakes of Colorectal Cancer Patients in Daegu·Gyeongbuk Area

대구·경북지역 대장직장암 환자의 식생활 태도와 영양소 섭취에 관한 환자-대조군 연구

  • 최영은 (대구가톨릭대학교 병원) ;
  • 김은정 (대구가톨릭대학교 식품영양학과)
  • Received : 2020.11.01
  • Accepted : 2020.11.17
  • Published : 2020.11.30
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Abstract

The incidence of colorectal cancer (CRC) in Korea has been gradually increased and it has been reported that dietary life is highly associated with the development of CRC. To investigate dietary attitudes and nutritional risk factors for CRC, we analyzed food intake of 34 patients diagnosed with CRC within 1 year and 51 subjects without gastrointestinal diseases as a control reside in Daegu·Gyeongbuk Area using semi-quantitative food frequency questionnaire. The results showed that dietary regularity and variety of food intake in control subjects was better than CRC patients whereas, CRC patients eat more frequently animal and vegetable protein foods, fried foods, green and yellow vegetables, and fruits than control subjects. Nutrient intake analysis showed that Vitamin A, E, K, C, sodium, magnesium, iodine, and cholesterol intake of CRC patients was higher than control subjects. Especially, after adjusting age and sex, regression analysis showed that Vitamin K (OR = 1.022, 95% Cl 1.003-1.043, p = 0.026) and sodium (OR = 1.001, 95% Cl 1.000-1.002, p = 0.032) were identified as risk factors for CRC. In the future, verification of the relationship between these nutrients and CRC risk and appropriate nutrient education will be needed for the prevention of CRC.

한국의 대장암 발병율은 점차 증가하고 있으며 대장암 발생은 식생활과 밀접하게 연관이 있는 것으로 보고되고 있다. 대장암 발생에 영향을 미칠 수 있는 식생활 태도 및 영양적 위험요인을 연구하기 위해 대구·경북지역에 거주하는 최근 1년 이내에 대장직장암으로 진단받은 환자 34명과 소화기계 질환이 없는 대조군 51명을 대상으로 식생활태도 및 반정량적 식품섭취빈도조사를 통한 영양섭취상태를 비교 분석하였다. 그 결과, 식사의 규칙성 및 식품섭취의 다양성은 대조군이 대장직장암 환자에 비해 높았으며 대장암 환자는 동식물성 단백질 섭취와 튀긴 음식, 그리고 녹황색 채소 및 과일류의 섭취가 대조군에 비해 높게 나타났다. 영양섭취분석에서는 대장직장암 환자가 대조군에 비해 비타민 A, E, K, C, 나트륨, 마그네슘, 요오드, 콜레스테롤의 섭취량이 유의적으로 높았으며 그 중 비타민 K와 나트륨 섭취는 대장직장암 발생의 위험요인으로 분석되었다. 향후 보다 많은 수의 연구대상자들을 통한 임상연구를 통하여 이들 영양소와 대장직장암 발생과의 상관관계를 확인하고 적절한 영양 교육을 시행한다면 대장직장암 발생의 위험을 예방하는데 도움이 될 것으로 사료된다.

Keywords

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