Archives of Craniofacial Surgery (대한두개안면성형외과학회지)

Korean Cleft Palate-Craniofacial Association (대한두개안면성형외과학회)
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Verrucous carcinoma arising from actinic keratosis: a case report

  • Jung, Ji Hyuk (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Jeon, Yeo Reum (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Kim, Hyo In (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital) ;
  • Lee, Mi Kyung (Department of Pathology, National Health Insurance Service Ilsan Hospital) ;
  • Chung, Seum (Department of Plastic and Reconstructive Surgery, National Health Insurance Service Ilsan Hospital)
  • Received : 2021.10.22
  • Accepted : 2021.12.09
  • Published : 2021.12.20
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Abstract

Verrucous carcinoma (VC) is a rare subtype of squamous cell carcinoma that commonly occurs in the oral cavity. However, VC of the facial skin is relatively rare. We report a case of a 91-year-old woman with VC of the facial skin in the left zygoma area. She was diagnosed with actinic keratosis (4×3 cm) of the same site approximately 12 years previously, but declined further treatment. The mass was excised with a minimum of 0.4 cm from gross margins with the result of free from tumor of all margins by frozen section, allowing for primary closure after skin undermining. Basal resection was performed in the preplatysmal plane. The diagnosis of VC was confirmed by histopathological examination. Postoperatively, the wound healed without incident and with no signs of facial nerve injury. To our knowledge, this is the first reported case of VC of facial skin arising from actinic keratosis.

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References

  1. Ackerman LV. Verrucous carcinoma of the oral cavity. Surgery 1948;23:670-8.
  2. Park YJ, Kwon GH, Kim JO, Kim NK, Ryu WS, Lee KS. A retrospective study of changes in skin cancer characteristics over 11 years. Arch Craniofac Surg 2020;21:87-91. https://doi.org/10.7181/acfs.2020.00024
  3. Grossman D, Leffell DJ. Squamous cell carcinoma. In: Freedberg IM, Eisen AZ, Wolff K, Austen KF, Goldsmith LA, Katz SI, editors. Fitzpatrick's dermatology in general medicine. 6th ed. New York: McGraw-Hill; 2003. p. 742-3.
  4. Han SH, Kim SH, Kim CK, Jo DI. Multiple nonmelanocytic skin cancers in multiple regions. Arch Craniofac Surg 2020;21:188-92. https://doi.org/10.7181/acfs.2020.00073
  5. Terada T. Verrucous carcinoma of the skin: aa report on 5 Japanese cases. Ann Diagn Pathol 2011;15:175-80. https://doi.org/10.1016/j.anndiagpath.2010.11.008
  6. Suh JM, Chung CH, Chang YJ. Head and neck reconstruction using free flaps: a 30-year medical record review. Arch Craniofac Surg 2021;22:38-44. https://doi.org/10.7181/acfs.2020.00745
  7. Wang N, Huang M, Lv H. Head and neck verrucous carcinoma: a population-based analysis of incidence, treatment, and prognosis. Medicine (Baltimore) 2020;99:e18660. https://doi.org/10.1097/md.0000000000018660
  8. Schwartz RA. Verrucous carcinoma of the skin and mucosa. J Am Acad Dermatol 1995;32:1-21. https://doi.org/10.1016/0190-9622(95)90177-9
  9. Diaz-Perez JL, Moreno J, Burgos J. Ackerman's verrucous carcinoma on the lower lip. Med Cutan Ibero Lat Am 1981;9:105-10.
  10. Chaudhary S, Bansal C, Ranga U. Verrucous carcinoma of the buccal mucosa with extension to the cheek. Cutis 2017;99:E16-8.
  11. Nguyen KQ, McMarlin SL. Verrucous carcinoma of the face. Arch Dermatol 1984;120:383-5. https://doi.org/10.1001/archderm.1984.01650390105024
  12. Patrascu V, Enache O, Ciurea R. Verrucous carcinoma: observations on 4 cases. Curr Health Sci J 2016;42:102-10.
  13. Depprich RA, Handschel JG, Fritzemeier CU, Engers R, Kubler NR. Hybrid verrucous carcinoma of the oral cavity: a challenge for the clinician and the pathologist. Oral Oncol Extra 2006;42:85-90. https://doi.org/10.1016/j.ooe.2005.09.006
  14. Martin F, Dalac S, Lambert D. Verrucous carcinoma. Nosologic aspects, apropos of 4 cases. Ann Dermatol Venereol 1995;122:399-403.
  15. Elmets CA. Cutaneous photo carcinogenesis. In: Mukhtar H, editor. Pharmacology of the skin. Boca Raton: CRC Press; 1992. p. 389-416.