Journal of Korean Society of Occupational and Environmental Hygiene (한국산업보건학회지)

Korean Industrial Hygiene Association (한국산업보건학회)
권호 표지
DOI QR코드

DOI QR Code

Assessing Hematological Change Associated with Cardiovascular Disease Risk among Korean Taxi Drivers Using Data from the Second (2012-2014) Korean National Environmental Health Survey: A Propensity Score Matching Approach

제2기(2012-2014) 국민환경보건 기초조사 자료를 활용한 국내 남성 택시 기사의 심혈관계 위험도 관련 혈액학적 변화에 대한 연구: 성향점수 매칭을 활용하여

  • Baek, Kiook (Department of Occupational and Environmental Medicine, Korea University Medical Center, Ansan Hospital)
  • 백기욱 (고려대학교 안산병원 직업환경의학과)
  • Received : 2021.08.23
  • Accepted : 2021.12.17
  • Published : 2021.12.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: Taxi drivers are exposed to various hazards, such as long periods of sedentary work and traffic-related air pollutants. However, studies on the health effects among taxi drivers in South Korea are insufficient. Methods: To assess subclinical hematologic change related to cardiovascular disease among male taxi drivers, we analyzed data from the second Korean National Environmental Health Survey. Fifty-nine taxi drivers and 1,912 controls were included in the analysis. Propensity score matching was performed to adjust for age, body mass index, and urinary cotinine. A total of 295 subjects were matched with 59 taxi drivers. Leukocyte count, platelet count, hematocrit, triglyceride, total cholesterol, HDL cholesterol land total IgE of the taxi drivers were compared with the control groups. Results: Taxi drivers showed significantly elevated blood leukocytes and platelets. Serum total IgE was significantly reduced in taxi drivers. However, blood leukocytes, platelets, and serum total IgE were not significantly correlated with work period among taxi drivers. Conclusions: Regarding the change of the blood leukocyte count, platelet count, and serum total IgE, taxi driving has the possibility to be associated with peripheral inflammation, humoral immunity and cardiovascular risk.

Keywords

References

  1. Ba AN, Verdin A, Cazier F, Garcon G, Thomas J et al. Individual exposure level following indoor and outdoor air pollution exposure in Dakar (Senegal). Environ Pollut 2019;248::397-407(http://dx.doi.org/10.1016/j.envpol.2019.02.042)
  2. Belkic K, Emdad R, Theorell T. Occupational profile and cardiac risk: possible mechanisms and implications for professional drivers. Int J Occup Med 1998; 11(1):37-57(http://dx.doi.org/
  3. Belkic K, Savic C, Theorell T, Rakic L, Ercegovac D et al. Mechanisms of cardiac risk among professional drivers. Scand J Work Environ Health 1994;20(2):73-86(http://dx.doi.org/ https://doi.org/10.5271/sjweh.1417
  4. Bellet S, Roman L, Kostis J. The effect of automobile driving on catecholamine and adrenocortical excretion. Am J Cardiol 1969;24(3):365-368(http://dx.doi.org/10.1016/0002-9149(69)90430-5)
  5. Benschop RJ, Rodriguez-Feuerhahn M, Schedlowski M. Catecholamine-induced leukocytosis: early observations, current research, and future directions. Brain Behav Immun 1996;10(2):77-91 (http://dx.doi.org/10.1006/brbi.1996.0009)
  6. Bigert C, Gustavsson P, Hallqvist J, Hogstedt C, Lewne M et al. Myocardial infarction among professional drivers. Epidemiology 2003;14(3):333-339(http://dx.doi.org/ https://doi.org/10.1097/01.EDE.0000057141.91012.80
  7. Bigert C, Klerdal K, Hammar N, Hallqvist J, Gustavsson P. Time trends in the incidence of myocardial infarction among professional drivers in Stockholm 1977-96. Occup Environ Med 2004;61(12):987-991(http://dx.doi.org/10.1136/oem.2004.012781)
  8. Bourdrel T, Bind M-A, Bejot Y, Morel O, Argacha J-F. Cardiovascular effects of air pollution. Arch Cardiovasc Dis 2017;110(11):634-642(http://dx.doi.org/10.1016/j.acvd.2017.05.003)
  9. Brookhart MA, Schneeweiss S, Rothman KJ, Glynn RJ, Avorn J et al. Variable selection for propensity score models. Am J Epidemiol 2006;163(12):1149-1156 (http://dx.doi.org/10.1093/aje/kwj149)
  10. Brucker N, Moro AM, Charao MF, Durgante J, Freitas F et al. Biomarkers of occupational exposure to air pollution, inflammation and oxidative damage in taxi drivers. Sci Total Environ 2013;463:884-893(http://dx.doi.org/10.1016/j.scitotenv.2013.06.098)
  11. Chen J, Chen Y, Chang W, Christiani D. Long driving time is associated with haematological markers of increased cardiovascular risk in taxi drivers. Occup Environ Med 2005; 62(12):890-894(http://dx.doi.org/10.1136/oem.2005.020354)
  12. Choi W, Kim S, Baek Y-W, Choi K, Lee K et al. Exposure to environmental chemicals among Korean adults-updates from the second Korean National Environmental Health Survey (2012-2014). Int J Hyg Environ Health 2017;220(2):29-35(http://dx.doi.org/10.1016/j.ijheh.2016.10.002)
  13. Criqui MH, Lee ER, Hamburger RN, Klauber MR, Coughlin S. IgE and cardiovascular disease: results from a population-based study. Am J Med 1987;82(5):964-968(http://dx.doi.org/10.1016/0002-9343(87)90159-8)
  14. Elshatarat RA, Burgel BJ. Cardiovascular risk factors of taxi drivers. J Urban Health 2016;93(3):589-606 (http://dx.doi.org/10.1007/s11524-016-0045-x.)
  15. Evans GW, Carrere S. Traffic congestion, perceived control, and psychophysiological stress among urban bus drivers. Am J Appl Psychol 1991;76(5):658 (http://dx.doi.org/10.1037/0021-9010.76.5.658)
  16. Farhangi MA, Keshavarz S-A, Eshraghian M, Ostadrahimi A, Saboor-Yaraghi A-A. White blood cell count in women: relation to inflammatory biomarkers, haematological profiles, visceral adiposity, and other cardiovascular risk factors. J Health Popul Nutr 2013;31(1):58(http://dx.doi.org/10.3329/jhpn.v31i1.14749.)
  17. Franco AT, Corken A, Ware J. Platelets at the interface of thrombosis, inflammation, and cancer. Am J Hematol 2015;126(5):582-588(http://dx.doi.org/10.1182/blood-2014-08-531582)
  18. Gagnon DR, Zhang T-J, Brand FN, Kannel WB. Hematocrit and the risk of cardiovascular disease- the Framingham study: a 34-year follow-up. Am Heart J 1994;127(3):674-682(http://dx.doi.org/10.1016/0002-8703(94)90679-3)
  19. Haim M, Boyko V, Goldbourt U, Battler A, Behar S. Predictive value of elevated white blood cell count in patients with preexisting coronary heart disease: the Bezafibrate Infarction Prevention Study. Archives of internal medicine 2004;164(4):433-439(http://dx.doi.org/doi:10.1001/archinte.164.4.433)
  20. Hannerz H, Tuchsen F. Hospital admissions among male drivers in Denmark. Occup Environ Med 2001;58(4):253(http://dx.doi.org/10.1136/oem.58.4.253)
  21. Hedberg G, Jacobsson K, Langendoen S, Nystrom L. Mortality in circulatory diseases, especially ischaemic heart disease, among Swedish professional drivers: A retrospective cohort study. J Hum Ergol 1991;20(1):1-5(http://dx.doi.org/
  22. Ince LM, Weber J, Scheiermann C. Control of Leukocyte Trafficking by Stress-Associated Hormones. Front Immunol 2018;9::3143(http://dx.doi.org/10.3389/fimmu.2018.03143)
  23. Jeong SM, Choi S, Kim K, Kim SM, Lee G et al. Effect of change in total cholesterol levels on cardiovascular disease among young adults. Am Heart J 2018;7(12):e008819(http://dx.doi.org/10.1161/JAHA.118.008819.)
  24. Jovanovic J, Batanjac J, Jovanovic M, Bulat P, Torbica N et al. Occupational profile and cardiac risks: mechanisms and implications for professional drivers. Int J Occup Med Environ Health 1998;11(2):145-152(http://dx.doi.org/
  25. Kurosaka K, Daida H, Muto T, WATANABE Y, KAWAI S et al. Characteristics of coronary heart disease in Japanese taxi drivers as determined by coronary angiographic analyses. Ind Health 2000;38(1):15-23(http://dx.doi.org/10.2486/indhealth.38.15)
  26. Langer RD, Criqui MH, Feigelson HS, McCann TJ, Hamburger RN. IgE predicts future nonfatal myocardial infarction in men. Journal of clinical epidemiology 1996;49(2):203-209(http://dx.doi.org/10.1016/0895-4356(95)00548-x)
  27. Leon-Latre M, Moreno-Franco B, Andres-Esteban EM, Ledesma M, Laclaustra M et al. Sedentary lifestyle and its relation to cardiovascular risk factors, insulin resistance and inflammatory profile. Rev Esp Cardiol 2014;67(6):449-455(http://dx.doi.org/10.1016/j.rec.2013.10.015)
  28. Li CY, Sung FC. A review of the healthy worker effect in occupational epidemiology. Occup Med 1999;49(4):225-229(http://dx.doi.org/10.1093/occmed/49.4.225)
  29. Lim S, Barratt B, Holliday L, Griffiths CJ, Mudway IS. Characterising professional drivers' exposure to traffic-related air pollution: Evidence for reduction strategies from in-vehicle personal exposure monitoring. Environ Int 2021;153::106532(http://dx.doi.org/10.1016/j.envint.2021.106532)
  30. Lippi G, Cervellin G, Sanchis-Gomar F. Immunoglobulin E (IgE) and ischemic heart disease. Which came first, the chicken or the egg? Ann Med 2014;46(7):456-463(http://dx.doi.org/ https://doi.org/10.3109/07853890.2014.927714
  31. Magen E, Mishal J, Vardy D. Selective IgE deficiency and cardiovascular diseases. Allergy Asthma Proc: OceanSide Publications; 2015. p. 225
  32. Martin WP, Sharif F, Flaherty G. Lifestyle risk factors for cardiovascular disease and diabetic risk in a sedentary occupational group: the Galway taxi driver study. Ir J Med Sci 2016;185(2):403-412(http://dx.doi.org/10.1007/s11845-016-1442-6)
  33. Min K-B, Min J-Y. Risk of cardiovascular mortality in relation to increased total serum IgE levels in older adults: a population-based cohort study. Int J Environ Res Public Health 2019;16(22):4350 (http://dx.doi.org/10.3390/ijerph16224350)
  34. Moller SV, Hannerz H, Hansen AM, Burr H, Holtermann A. Multi-wave cohort study of sedentary work and risk of ischemic heart disease. Scand J Work Environ Health 2016;42(1):43-51(http://dx.doi.org/10.5271/sjweh.3540)
  35. Mortensen MB, Nordestgaard BG. Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70-100 years: a contemporary primary prevention cohort. The Lancet 2020;396 (10263):1644-1652(http://dx.doi.org/10.1016/S0140-6736(20)32233-9)
  36. Nasri H, Moazenzadeh M. Coronary artery disease risk factors in drivers versus people in other occupations. Arya Atherosclerosis 2010;2(2)
  37. National Institute of Environmental Research (NIER). Guideline for Biological Specimens Management on The Second Stage Korean National Environmental Health Survey I: Korea Ministry of Environment; 2012. p. 7-27
  38. National Institute of Environmental Research (NIER). Manual for Analysis of Environmental Pollutants in Biological Samples (Organic Chemicals): Korea Ministry of Environment; 2015. p. 21-33
  39. Nordestgaard BG, Varbo A. Triglycerides and cardiovascular disease. The Lancet 2014;384(9943):626-635(http://dx.doi.org/10.1016/S0140-6736(14)61177-6)
  40. Rader DJ, Hovingh GK. HDL and cardiovascular disease. The Lancet 2014;384(9943):618-625(http://dx.doi.org/10.1016/S0140-6736(14)61217-4)
  41. Rage E, Jacquemin B, Nadif R, Oryszczyn MP, Siroux V et al. Total serum IgE levels are associated with ambient ozone concentration in asthmatic adults. Allergy 2009;64(1):40-46(http://dx.doi.org/10.1111/j.1398-9995.2008.01800.x)
  42. Rahimpour F, Jarahi L, Rafeemanesh E, Taghati A. Assessment of occupational stress in taxi drivers and its relation with cardiovascular risk factors. Occup Med (Lond) 2016;8(2):51-61(http://dx.doi.org/
  43. Rassen JA, Shelat AA, Myers J, Glynn RJ, Rothman KJ et al. One-to-many propensity score matching in cohort studies. Pharmacoepidemiol Drug Saf 2012;21::69-80(http://dx.doi.org/10.1002/pds.3263)
  44. Rezaei Hachesu V, Naderyan Feli S, Zare Sakhvidi MJ. Prevalence of cardiovascular risk factors among taxi drivers in Yazd, Iran, 2016. J Community Health Res 2017;6(4):200-206(http://dx.doi.org/
  45. Sabatine MS, Morrow DA, Cannon CP, Murphy SA, Demopoulos LA et al. Relationship between baseline white blood cell count and degree of coronary artery disease and mortality in patients with acute coronary syndromes: a TACTICS-TIMI 18 substudy. J Am Coll Cardiol 2002;40(10):1761-1768 (http://dx.doi.org/10.1016/s0735-1097(02)02484-1)
  46. Salvi S. Health effects of ambient air pollution in children. Paediatr Respir Rev 2007;8(4):275-280(http://dx.doi.org/10.1016/j.prrv.2007.08.008)
  47. Sangaleti CT, Trincaus MR, Baratieri T, Zarowy K, Ladika MB et al. Prevalence of cardiovascular risk factors among truck drivers in the South of Brazil. BMC Public Health 2014;14(1):1-9(http://dx.doi.org/10.1186/1471-2458-14-1063)
  48. Sloan A, Gona P, Johnson AD. Cardiovascular correlates of platelet count and volume in the Framingham Heart Study. Ann Epidemiol 2015;25(7):492-498 (http://dx.doi.org/10.1016/j.annepidem.2015.01.010)
  49. Tuchsen F, Hannerz H, Roepstorff C, Krause N. Stroke among male professional drivers in Denmark, 1994-2003. Occup Environ Med 2006;63(7):456-460 (http://dx.doi.org/10.1136/oem.2005.025718)
  50. Vinholt PJ, Hvas A-M, Frederiksen H, Bathum L, Jorgensen MK et al. Platelet count is associated with cardiovascular disease, cancer and mortality: a population-based cohort study. Thromb Res 2016;148:136-142(http://dx.doi.org/10.1016/j.thromres.2016.08.012)
  51. Willis EA, Shearer JJ, Matthews CE, Hofmann JN. Association of physical activity and sedentary time with blood cell counts: National Health and Nutrition Survey 2003-2006. PLoS One 2018;13(9):e0204277(http://dx.doi.org/10.1371/journal.pone.0204277)