Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Canine Multicentric Large B Cell Lymphoma with Increased Mott Cells Diagnosed by Flow Cytometry

  • Yang, Yeseul (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Jung, Jae-Ha (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Hwang, Sung-Hyun (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University) ;
  • Kim, Yongbaek (Laboratory of Clinical Pathology, College of Veterinary Medicine, Seoul National University)
  • Received : 2020.10.29
  • Accepted : 2021.01.25
  • Published : 2021.02.28
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Abstract

A 12-year-old dog was referred due to multiple superficial lymphadenopathy. On cytology, each lymph node showed different cell populations where some of them consisted of intermediate to large lymphocytes with frequent Mott cells. Presence of Mott cells along with immature lymphocytes made the cytological diagnosis challenging, and therefore, supplementary diagnostic tests including PCR for Antigen Receptor Rearrangement (PARR) assay and flow cytometry were performed. This case report illustrates the value of flow cytometry in the diagnosis of lymphadenopathy with ambiguous cytologic findings.

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References

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