DOI QR코드

DOI QR Code

Comparative Observational Study on the Effects of Intra-articular Hominis Placenta Pharmacopuncture and Acupoint Hominis Placenta Pharmacopuncture for Knee Osteoarthritis Patients

  • Park, Yeo-bin (Department of Acupuncture and Moxibustion Medicine, Samse Korean Medicine Hospital) ;
  • Ahn, Chang Beohm (Department of Acupuncture and Moxibustion Medicine, Samse Korean Medicine Hospital) ;
  • Park, Yun-Leong (Department of Acupuncture and Moxibustion Medicine, Samse Korean Medicine Hospital) ;
  • Baek, Ji-Won (Samse Korean Medicine Hospital) ;
  • Kong, Won-Ho (Samse Korean Medicine Hospital) ;
  • Kim, Bo-Sung (Samse Korean Medicine Hospital) ;
  • Lee, Bong-ho (Samse Korean Medicine Hospital) ;
  • Jang, Sun-hee (Department of Acupuncture and Moxibustion Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Song, Choon-ho (Department of Acupuncture and Moxibustion Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Yoon, Hyun-min (Department of Acupuncture and Moxibustion Medicine, College of Oriental Medicine, Dong-Eui University) ;
  • Kim, Cheol-hong (Department of Acupuncture and Moxibustion Medicine, College of Oriental Medicine, Dong-Eui University)
  • Received : 2020.11.26
  • Accepted : 2021.01.22
  • Published : 2021.02.28

Abstract

The aim of this case report was to observe the effects of intra-articular hominis placenta pharmacopuncture (HPP). Based on the medical records patients who received intra-articular treatment or received acupoint pharmacopuncture treatment, a comparison was made. There were 35 patients who were hospitalized for degenerative osteoarthritis of the knee joint from the 1st October 2019 to 26th September 2020. There were 14 patients who were treated with HPP in the intra-articular joint space (Group A), and 14 patients who were treated with HPP at specific acupoints (Group B). The outcome effects were measured using the Korean Western Ontario and Mc (KWOMAC) the visual analog scale (VAS) before the first treatment, and after the fifth treatment. The KWOMAC (p < 0.001) and the VAS scores (p < 0.001) in Groups A and B significantly improved after treatment compared with before treatment. When comparing Group A improvement with Group B improvement using the KWOMAC there was no statistically significant difference however, when using the VAS scores, Group A treatment was statistically more effective compared with Group B (p = 0.002). This study indicated that HPP may be an effective treatment for knee osteoarthritis. Moreover, intra-articular HPP may be more effective than acupoint HPP for knee osteoarthritis.

Keywords

References

  1. So KY, Lee HY. Septic Arthritis after Intra-articular Hyaluronic Acid Injections in Patients with Knee Osteoarthritis-A report of two cases. Korean J Pain 2002;15:80-83.
  2. Moskowitz RW. Osteoarthritis. 4th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2007. 528 p.
  3. Ling SM, Bathon JM. Osteoarthritis in older adults. J Am Geriatr Soc 1998;46:216-225. https://doi.org/10.1111/j.1532-5415.1998.tb02543.x
  4. Yoh SB, Sul JU, Shin MS. Research trends on the treatment of knee osteoarthritis in Korean medicine. Korean J Acupunct 2011;28:139-155.
  5. Park MS, Oh SJ, Lee JH, Jun SA, Gong HM, Choi SH et al. Miniscalpel Acupuncture Treatment on a Knee Degenerative Osteoarthritis Patient Non-responsive to Acupuncture Treatment. J Acupunct Res 2016;33:161-168. https://doi.org/10.13045/acupunct.2016043
  6. Song KH, Lee JS, Jo JH, Park KB. Study on the clinical effects of homnis placenta herbal acupuncture on osteoarthritis of knee joint. J Acupunct Res 2006;23:163-173.
  7. Lee DE, Park WH, Cha YY. The case report of chronic ankle sprain improved with hominis placenta pharmacopuncture treatment. J Korean Med Rehabil 2016;26:171-181. https://doi.org/10.18325/jkmr.2016.26.3.171
  8. Song KC, Seo JY, Cho MU, Song SB, Choi BS, Ryu WH et al. Case Report of Patients Diagnosed with Spinal Stenosis Treated by Hominis Placenta Megadose Pharmacopuncture Combined with Korean Medicine Treatment. J Physiol Pathol Korean Med 2018;32:141-147. https://doi.org/10.15188/kjopp.2018.04.32.2.141
  9. Seo BI, Kim SC. Bonchojibseong. Seoul (Korea): Tree & Earth; 2000. p. 803-804.
  10. Committee of Herbalogy Society. Clinical Herbal Medicine. Seoul (Korea): Younglimsa; 2006. p. 567-568.
  11. Lee GJ. Pharmacopuncturology. Seoul (Korea): Hanmi; 2019. 247 p.
  12. Na WM, Lee SY, Jang EH, Moon HC, Kim SM, Yoon CH et al. A Study on Pain relief effects and Allergic responses for the Osteoarthritis of the knee joint Between Sweet Bee Venom and Bee Venom Pharmacopuncture. J Pharmacopuncture 2007;10:47-55.
  13. Lee SH, Kwon GS, Kang MS, Yoon HM, Kim CH. Comparative study on the effects of bee venom pharmacopuncture according to the treatment method for knee osteoarthritis. J Pharmacopuncture 2012;15:7-14.
  14. Ryu SM, Lee JS, Kim SS, Jung SH. The Effect of Intra-articular Bee Venom Injection on Osteoarthritis of the Knee. J Orient Rehabil Med 2004;14:35-52.
  15. Saunders S, Longworth S. Injection Techniques in Musculoskeletal Medicine. Seoul (Korea): Elsevier Korea LCC; 2012. 174 p.
  16. Bae SC, Lee HS, Yun H, Kim TH, Yoo DH, Kim S. Cross-cultural adaptation and validation of Korean Western Ontario and McMaster Universities (WOMAC) and Lequesne osteoarthritis indices for clinical research. Osteoarthritis Cartilage 2001;9:746-750. https://doi.org/10.1053/joca.2001.0471
  17. Korean Orthopaedic Association. Orthopaedics. Seoul (Korea): Newest Medicine Company; 1999. p. 195, 517.
  18. Korean pharmacopuncture institute. Outline of herbal acupuncture therapy. Seoul (Korea): Korean Pharmacopuncture institute; 1999. p. 318, 323.
  19. Kim JK, Kim TH, Park SW, Kim HY, Kim SH, Lee SY et al. Protective effects of human placenta extract on cartilage degradation in experimental osteoarthritis. Biol Pharm Bull 2010;33:1004-1010. https://doi.org/10.1248/bpb.33.1004
  20. Yeom MJ, Kang JE, Hahm DH, Park HJ, H Lee EJ, Shim IS et al. Therapeutic effects of hominis placenta herb-acupuncture in adjuvant-induced arthritis in rats. J Pharmacopuncture 2002;5:91-103. https://doi.org/10.3831/KPI.2002.5.1.091
  21. Bae JM, Lee HY, Park JE, Lee YJ, Jeong SY, Jo JH et al. Evaluation of Medical Technology on the Effectiveness and Safety of Placenta Injection. National Evidence-based Healthcare Collaborating Agency; 2010. p. 47, 144.
  22. Huh J, Suh MS, Park SJ, Lim YK, Shin JH, Chung HY et al. The effect of placenta extract on proliferation and differentiation of human chondrocytes. Arch Plast Surg 2006;33:616-620.
  23. Lee KH, Kim TH, Lee WC, Kim SH, Lee SY, Lee SM. Anti-inflammatory and analgesic effects of human placenta extract. Nat Prod Res 2011;25:1090-1100. https://doi.org/10.1080/14786419.2010.489050