Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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Estimation of Temporal Acute Exposure Guideline Levels for Emergency Response - A Brief Case using Formaldehyde -

화학사고 대응을 위한 시간별 급성노출기준 참고치 산정 - 폼알데하이드 사례 -

  • Kim, Eunchae (Department of Occupational Health, Daegu Catholic University) ;
  • Cho, Yong-Sung (Accident Prevention Assessment Division 2, National Institute of Chemical Safety, Ministry of Environment) ;
  • Lee, Chung-Soo (Accident Response Coordination Division, National Institute of Chemical Safety, Ministry of Environment) ;
  • Yang, Wonho (Department of Occupational Health, Daegu Catholic University) ;
  • Hwang, Seung-Ryul (Accident Response Coordination Division, National Institute of Chemical Safety, Ministry of Environment) ;
  • Park, Jihoon (Accident Response Coordination Division, National Institute of Chemical Safety, Ministry of Environment)
  • 김은채 (대구가톨릭대학교 산업보건학과) ;
  • 조용성 (환경부 화학물질안전원 사고예방심사2과) ;
  • 이청수 (환경부 화학물질안전원 사고대응총괄과) ;
  • 양원호 (대구가톨릭대학교 산업보건학과) ;
  • 황승율 (환경부 화학물질안전원 사고대응총괄과) ;
  • 박지훈 (환경부 화학물질안전원 사고대응총괄과)
  • Received : 2021.04.01
  • Accepted : 2021.04.20
  • Published : 2021.04.30
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Abstract

Objectives: This study aimed to provide temporal Acute Exposure Guideline Levels (AEGL) for a hazardous substance as a pilot study. Methods: As one of the substances designated by the Korea Ministry of Environment as requiring preparations for potential accidents, formaldehyde was selected to estimate the AEGLs. The calculation was based on Haber's formula (Cn×t=k) using valid toxicity data (for humans/animals). A total of 96 points of AEGL levels were provided using an interval of five minutes over eight hours. Results: The AEGL-1 and 2 values were constant for the entire exposure duration at 0.9 ppm and 14 ppm, respectively. The values were obtained from clinical/animal tests, and the adaptation effect after a given exposure duration was also considered. AEGL-3 was based on animal toxicity data, and it was estimated from 127 ppm for the initial five minutes to 35 ppm for eight hours. Conclusions: More specific AEGL levels for formaldehyde could be obtained in this study using toxicity data with Haber's formula. Based on this methodology, it would be also possible to estimate AEGL levels that can be used at the scene of a chemical accident for other substances requiring preparation for potential accidents.

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