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Two Cases of Tinea Faciei Mimicking Eczema Herpeticum in Siblings

단순 포진 감염으로 오인된 자매에서 발생한 소아 얼굴 백선 2 례

  • Hwang, JiHoon (Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Kang, Ji-Man (Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Ahn, Jong Gyun (Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine)
  • 황지훈 (연세대학교 의과대학 소아과학교실, 세브란스 어린이병원 소아청소년과) ;
  • 강지만 (연세대학교 의과대학 소아과학교실, 세브란스 어린이병원 소아청소년과) ;
  • 안종균 (연세대학교 의과대학 소아과학교실, 세브란스 어린이병원 소아청소년과)
  • Received : 2020.09.18
  • Accepted : 2020.11.01
  • Published : 2021.04.25

Abstract

Tinea faciei is a rare dermatophyte infection of the face that most often appears as a facial rash, followed by patches of small and raised bumps. Since it is uncommon in children and has similar rash patterns with various skin diseases, it is likely to be misdiagnosed as herpes simplex infection, contact dermatitis, disc-shaped lupus erythematosus, acne, and atopic dermatitis. In this case, siblings aged 3 and 4 were hospitalized due to skin rashes that occurred after traveling to Vietnam, and were administered antiviral drugs and systemic steroids under suspicion of herpes simplex infection with atopic dermatitis. Despite administration of these drugs, skin lesions did not show improvement. Serum beta-D-glucan assays were elevated in both patients, and after approximately 2 weeks, Trichophyton interdigitale was cultured in the older sister's skin fungal culture test. Both patients recovered after local and systemic antifungal therapy, without relapse or side effects. Skin lesions on the face, which do not respond to the existing treatment in children, should be checked for the possibility of tinea faciei through repeated fungal tests, and the beta-D-glucan assay can be a useful tool in diagnosing tinea faciei.

얼굴 백선은 얼굴에 발생하는 드문 피부 사상균 감염으로, 붉은 발진과 함께 작은 융기가 있는 피부 병변이 특징적이다. 소아에서 얼굴 백선은 흔하지 않으며 다양한 피부질환과 발진 양상이 유사하여, 단순포진감염, 접촉 피부염, 원판형 홍반성 루푸스, 여드름, 아토피 피부염 등으로 오진 될 수 있다. 본 증례에서는 4살, 3살의 자매가 베트남 여행을 다녀온 후 발생한 피부염으로 본원에 내원하였고, 아토피 피부염에 합병된 단순포진감염을 의심하여 항바이러스제제 및 전신 스테로이드 제제를 투약하였으나, 경과는 호전되지 않았다. 혈액 검사상 혈청 beta-D-glucan 수치가 두 환자 모두에서 상승되어 있었고, 약 2주 후 언니의 피부 진균 배양 검사에서 T. interdigitale이 동정 되었다. 두 환자 모두 국소 및 전신 항진균 요법 후 재발이나 부작용 없이 회복되었다. 소아에서 기존 치료에 반응하지 않는 얼굴의 피부 병변은 반드시 진균 검사를 통해서 얼굴 백선의 가능성을 확인해야 하며, beta-D-glucan 검사는 보조적 수단으로서 얼굴 백선 진단에 도움을 줄 수 있다.

Keywords

References

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