Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Characteristics of Source Acupoints: Data Mining of Clinical Trials Database

데이터 마이닝을 이용한 임상연구 데이터베이스 기반 원혈의 주치 특성

  • Choi, Dha-Hyun (Acupuncture and Meridian Science Research Center, Kyung Hee University) ;
  • Lee, Seoyoung (Acupuncture and Meridian Science Research Center, Kyung Hee University) ;
  • Lee, In-Seon (Acupuncture and Meridian Science Research Center, Kyung Hee University) ;
  • Ryu, Yeonhee (KM Fundamental Research Division, Korea Institute of Oriental Medicine) ;
  • Chae, Younbyoung (Acupuncture and Meridian Science Research Center, Kyung Hee University)
  • 최다현 (경희대학교 침구경락융합연구센터) ;
  • 이서영 (경희대학교 침구경락융합연구센터) ;
  • 이인선 (경희대학교 침구경락융합연구센터) ;
  • 류연희 (한국한의학연구원 임상의학부) ;
  • 채윤병 (경희대학교 침구경락융합연구센터)
  • Received : 2021.04.16
  • Accepted : 2021.06.20
  • Published : 2021.06.27
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Abstract

Objectives : Source acupoint is one of the representative acupoints to treat various diseases in each meridian. We aimed to identify the patterns of selection of Source acupoints and their associations with diseases using clinical trials data. Methods : We extracted the frequency of Source acupoints across 30 diseases from clinical trials database. Acupuncture treatment regimens were retrieved from the Cochrane Database of Systematic Reviews. The frequency of Source acupoint use was calculated as the number of studies using a certain acupoint divided by the total number of included studies. Using hierarchical clustering and multidimensional scaling, the characteristics of Source acupoints were analyzed based on the similarity of the relationships between the Source acupoints and the diseases. Results : A total of 421 clinical trials were included for this analysis. LR3, HT7, KI3, and LI4 acupoints were most frequently used for the treatment of 30 diseases. Cluster analysis showed that LR3 and LI4 acupoints were grouped together and HT7 and KI3 acupoints were grouped together. Multidimensional scaling revealed that LR3, LI4, HT7, and KI3 acupoints have intrinsic properties in the two-dimensional space. Conclusions : The present study identified the selection patterns of the Source acupoints using clinical trials data. Our finding will provide the understanding of the characteristics of Source acupoints.

Keywords

Acknowledgement

This research was supported by Korea Institute of Oriental Medicine (KSN1812181).

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