Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Recent Research Trends of Acupuncture for Wrinkle Treatment

주름 개선을 위한 침 연구의 현황분석

  • Jung, Hyeon-Suk (Department of Korean Medicine, College of Korean Medicine, Daejeon University) ;
  • Kim, Tae-Jun (Department of Korean Medicine, College of Korean Medicine, Daejeon University) ;
  • Park, Ji-Yeun (Department of Korean Medicine, College of Korean Medicine, Daejeon University)
  • 정현석 (대전대학교 한의과대학 한의학과) ;
  • 김태준 (대전대학교 한의과대학 한의학과) ;
  • 박지연 (대전대학교 한의과대학 한의학과)
  • Received : 2021.05.17
  • Accepted : 2021.06.06
  • Published : 2021.06.27
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Abstract

Objectives : The aim of this study is to analyze the effect of acupuncture and the details of acupuncture treatment methods on skin wrinkles. Methods : Search was conducted in Pubmed, KISS, and NDSL databases for acupuncture studies on skin wrinkles. The detailed therapeutic techniques of acupuncture used for skin wrinkles and the effect of acupuncture on skin wrinkle improvement were analyzed. Then, the study results using the same indicator were compared through meta-analysis in order to compare the effects of acupuncture with the control group. The quality of randomized controlled trials (RCTs) was assessed using the risk of bias (ROB) assessment tool (Ver. 1.0, Cochrane Collaboration). Results : A total of 10 RCTs and 19 case series were included in this study. The most frequently used therapeutic technique for skin wrinkle improvement was Microneedle therapy system (MTS, n=19), and they were mostly used with aesthetic solutions (13 out of 19 studies). Skin wrinkle related indexes were most commonly used to evaluate skin wrinkle improvement (n=14). Panax Ginseng pharmacopuncture showed the most remarkable effect in improving the range of skin wrinkles and the depth of skin wrinkles. MTS+epidermal growth factor improved the levels of skin hydration, skin elasticity, and variation of skin pigment the most. MTS+Endothelial precursor cell improved the number of skin melanin the most. Three RCTs included in the meta-analysis showed moderate ROB on average. Conclusions : Acupuncture treatment was effective in improving skin wrinkles. However, a precise study design using unified indicators and appropriate controls needs to be performed in further studies in order to establish more convincing evidence of the effectiveness of acupuncture for improving skin wrinkles.

Keywords

Acknowledgement

This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2018R1C1B3004424).

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