Korean Journal of Food Science and Technology (한국식품과학회지)

Korean Society of Food Science and Technology (한국식품과학회)
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Residue analysis and risk assessment of ethoxyquin and ethoxyquin dimer in farmed fish

양식어류 중 Ethoxyquin과 Ethoxyquin dimer의 잔류분석 및 위해평가

  • Choi, Young-Hee (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Ko, Suk-Kyung (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Ryu, Seung-Hee (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Jin, Young-Hee (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Kwak, Jae-Eun (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Lee, Myung-Sook (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Kim, Bog-Soon (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment) ;
  • Hang, In-Sook (Department of Gangnam Agricultural and Fishery Product Inspection, Seoul Metropolitan Government Research Institute of Public Health and Environment)
  • 최영희 (서울시보건환경연구원 강남농수산물검사소) ;
  • 고숙경 (서울시보건환경연구원 강남농수산물검사소) ;
  • 류승희 (서울시보건환경연구원 강남농수산물검사소) ;
  • 진영희 (서울시보건환경연구원 강남농수산물검사소) ;
  • 곽재은 (서울시보건환경연구원 강남농수산물검사소) ;
  • 이명숙 (서울시보건환경연구원 강남농수산물검사소) ;
  • 김복순 (서울시보건환경연구원 강남농수산물검사소) ;
  • 황인숙 (서울시보건환경연구원 강남농수산물검사소)
  • Received : 2021.02.03
  • Accepted : 2021.03.22
  • Published : 2021.06.30
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Abstract

In the present study, liquid chromatography tandem-mass spectrometry was used to conduct a risk assessment of ethoxyquin and ethoxyquin dimer residues in 288 farmed fish sold in wholesale and traditional markets in Seoul. The detection range (detection rate) of ethoxyquin and ethoxyquin dimer was 0.005~0.309 mg/kg (4.9%) and 0.001~2.828 mg/kg (69.8%), respectively. Ethoxyquin was detected only in freshwater eels, loaches, catfish, and flatfish, whereas ethoxyquin dimer was present in all fish species. To estimate the dietary exposure levels of ethoxyquin and ethoxyquin dimer, the hazard index, calculated using the acceptable daily intake and estimated daily intake, ranged from 0.001 to 0.300%. Our results indicate that there is no significant exposure risk to humans from these farmed fish despite 10 farmed fish samples exceeding the maximum residue level (1.0 mg/kg as the sum of ethoxyquin and ethoxyquin dimer).

서울시내 도매시장 및 재래시장에서 판매되는 양식어류 288건에 대해 에톡시퀸과 에톡시퀸 다이머의 잔류량을 LC-MS/MS로 분석하고 위해평가를 수행하였다. 에톡시퀸과 에톡시퀸 다이머의 검출 범위(검출률)는 각각 민물어류의 경우 0.005-0.309 mg/kg (15.7%), 0.002-2.828 mg/kg (90.0%), 해양어류의 경우 0.009-0.024 mg/kg (2.5%), 0.001-1.790 (63.3%)로 나타났다. 에톡시퀸은 민물장어, 미꾸라지, 동자개, 넙치에서만 검출된 반면 에톡시퀸 다이머는 민물어류 5종 및 해양어류 6종에서 검출되었다. 식이노출평가를 위해 ADI와 EDI를 이용하여 미꾸라지, 민물장어, 돔, 넙치 우럭을 대상으로 HI를 계산한 결과 0.002-0.301%로 나타났다. 본 연구 결과, 10건의 양식 어류가 잔류물질 허용기준 1.0 mg/kg을 초과하였지만, 인체 건강에 잠재적인 위해성이 매우 적은 것으로 나타났다. 하지만 이번 연구 결과는 식품에 허가되어 있지 않는 항산화제인 에톡시퀸 및 에톡시퀸 다이머가 사료로부터 양식어류에 이행되어 인간에게 노출되고 있음을 과학적으로 입증할 수 있는 근거 자료가 되었다.

Keywords

References

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