Acknowledgement
This work was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science (NRF-2020R1F1A1073007).
References
- Adeyinka A, Kondamudi NP. Cholinergic crisis [Internet]. StatPearls Publishing, Treasure Island (FL), 2021 Jan [updated 2021 Feb 26; cited 2021 Apr 17]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482433/.
- Foy DS, Trepanier LA, Shelton GD. Cholinergic crisis after neostigmine administration in a dog with acquired focal myasthenia gravis. J Vet Emerg Crit Care (San Antonio) 2011;21:547-551.
- Ohbe H, Jo T, Matsui H, Fushimi K, Yasunaga H. Cholinergic crisis caused by cholinesterase inhibitors: a retrospective nationwide database study. J Med Toxicol 2018;14:237-241. https://doi.org/10.1007/s13181-018-0669-1
- Jin M, Son M. DA-9701 (Motilitone): A multi-targeting botanical drug for the treatment of functional dyspepsia. Int J Mol Sci 2018;19:4035. https://doi.org/10.3390/ijms19124035
- Kwon YS, Son M. DA-9701: A new multi-acting drug for the treatment of functional dyspepsia. Biomol Ther (Seoul) 2013;21:181-189. https://doi.org/10.4062/biomolther.2012.096
- Lee TH, Kim KH, Lee SO, Lee KR, Son M, Jin M. Tetrahydroberberine, an isoquinoline alkaloid isolated from corydalis tuber, enhances gastrointestinal motor function. J Pharmacol Exp Ther 2011;338:917-924. https://doi.org/10.1124/jpet.111.182048
- Sarasamma S, Audira G, Juniardi S, Sampurna BP, Liang ST, Hao E, Lai YH, Hsiao CD. Zinc chloride exposure inhibits brain acetylcholine levels, produces neurotoxic signatures, and diminishes memory and motor activities in adult zebrafish. Int J Mol Sci 2018;19:3195. https://doi.org/10.3390/ijms19103195
- Gutierrez J, Gazzano A, Torracca B, Meucci V, Mariti C. Determination of prolactin in canine saliva: is it possible to use a commercial ELISA kit? Animals (Basel) 2019;9:418. https://doi.org/10.3390/ani9070418
- Lee S, Lee D, Baek J, Jung EB, Baek JY, Lee IK, Jang TS, Kang KS, Kim KH. In vitro assessment of selected Korean plants for antioxidant and antiacetylcholinesterase activities. Pharm Biol 2017;55:2205-2210. https://doi.org/10.1080/13880209.2017.1397179
- Xiao HT, Peng J, Liang Y, Yang J, Bai X, Hao XY, Yang FM, Sun QY. Acetylcholinesterase inhibitors from Corydalis yanhusuo. Nat Prod Res 2011;25:1418-1422. https://doi.org/10.1080/14786410802496911
- Stewart WC. Accumulation of acetylcholine in brain and blood of animals poisoned with cholinesterase inhibitors. Br J Pharmacol Chemother 1952;7:270-276. https://doi.org/10.1111/j.1476-5381.1952.tb01322.x
- Lee TH, Choi JJ, Kim DH, Choi S, Lee KR, Son M, Jin M. Gastroprokinetic effects of DA-9701, a new prokinetic agent formulated with Pharbitis Semen and Corydalis Tuber. Phytomedicine 2008;15:836-843. https://doi.org/10.1016/j.phymed.2008.02.019
- Kim ER, Min BH, Lee SO, Lee TH, Son M, Rhee PL. Effects of DA-9701, a novel prokinetic agent, on gastric accommodation in conscious dogs. J Gastroenterol Hepatol 2012;27:766-772. https://doi.org/10.1111/j.1440-1746.2011.06924.x
- Kim ER, Min BH, Lee TH, Son M, Rhee PL. Effect of DA-9701 on colorectal distension-induced visceral hypersensitivity in a rat model. Gut Liver 2014;8:388-393. https://doi.org/10.5009/gnl.2014.8.4.388
- Plumb DC. Plumb's Veterinary Drug Handbook. 9th ed. Wiley-Blackwell, Chichester, 2018.