Journal of The Korean Society of Clinical Toxicology (대한임상독성학회지)

Korean society of Clincal Toxicology (대한임상독성학회)
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Comparison of Poisoning Severity Score (PSS) according to alcohol co-ingestion in intentional poisoning patients

의도적인 중독 환자들의 음주 여부에 따른 중독 중증도 지수의 비교

  • Jun, Min jae (Department of Emergency Medicine, Inha University School of Medicine) ;
  • Ahn, Tae kyu (Department of Emergency Medicine, Inha University School of Medicine) ;
  • Kang, Soo (Department of Emergency Medicine, Inha University School of Medicine)
  • 전민재 (인하대학교 의과대학 응급의학교실) ;
  • 안태규 (인하대학교 의과대학 응급의학교실) ;
  • 강수 (인하대학교 의과대학 응급의학교실)
  • Received : 2021.02.04
  • Accepted : 2021.03.31
  • Published : 2021.06.30
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Abstract

Purpose: Alcohol ingestion enhances impulsivity and aggression, and has been proven to have a close relationship with suicide. This study investigates whether alcohol co-ingestion affects the Poisoning Severity Score (PSS) grade in patients with intentional poisoning. Methods: We conducted a retrospective analysis of intentional poisoning patients who visited the emergency department (ED) from January 1 to December 31, 2020. Patients were divided into non-drunken and drunken groups. We collected the data based on the medical records of the patients and serum ethanol level results recorded during initial blood tests at the ED. To grade the PSS, the highest score was assessed through clinical signs and test results during the hospital stay. A comparative analysis was conducted between the two groups. Results: A total of 277 patients were included in the study. 163 (58.8%) were in the non-drunken group, and 114 (41.2%) were in the drunken group. The PSS grade showed a significant difference between the two groups (p=0.002). While grade 1 (mild) was observed more in the non-drunken group, grade 2 (moderate) and grade 3 (severe) were seen more in the drunken group. In an ordinal logistic regression analysis, alcohol co-ingestion (adjusted odds ratio [aOR] 2.557, 95% confidence interval [CI] 1.554-4.208, p<0.001) was considered to be a risk factor for a higher PSS grade. There was no significant correlation between the serum ethanol level and the PSS grade. (p=0.568) Conclusion: Intentional poisoning patients with alcohol co-ingestion had a higher PSS. Hence close observation and aggressive treatment in the ED is warranted in such cases.

Keywords

Acknowledgement

본 연구를 위해 자료 수집에 도움을 주신 인하대학교 부속병원 생명사랑위기대응센터의 장가희 선생님과 강은정 선생님께 감사를 표합니다.

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