DOI QR코드

DOI QR Code

A Combination of Herbal Medicine and Moxibustion Treatment is Effective for a Recalcitrant Cutaneous Warts in a Pediatric Patient: A Case Report

  • Lee, Ji-Yeon (Department of Sasang Constitutional Medicine, Kyung Hee University Hospital at Gangdong) ;
  • Kim, Sul-Ki (College of Korean Medicine, Daejeon University) ;
  • Jeon, Cheon-Hoo (College of Korean Medicine, Daejeon University) ;
  • Shim, Soo-Bo (College of Korean Medicine, Daejeon University) ;
  • Ahn, Hae In (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development) ;
  • Kim, NamKwen (Guideline Center for Korean Medicine, National Institute for Korean Medicine Development)
  • 투고 : 2021.07.06
  • 심사 : 2021.07.27
  • 발행 : 2021.08.31

초록

Although warts are a common skin condition/disease that recurs in childhood, treatment completion is difficult owing to the pain associated with conventional therapies. In this case, Korean herbal medicine, Guijakjihwang-Tang, and indirect moxibustion was used to treat a recalcitrant cutaneous wart without pain and recurrence. A 7-year-old boy presented with recurrent cutaneous warts on his right hand and received cryotherapy 3 times in the previous year. The wart recurred during the course of cryotherapy treatment, and the patient did not want to suffer any more pain from the previous treatment. Therefore, parents sought an efficient and painless therapy. The patient was treated for 2 months using Guijakjihwang-Tang combined with indirect moxibustion. The prominent lesion separated in the 2nd month of treatment and completely recovered without adverse events in the 3rd month. There was no recurrence over 12 months of follow-up. This report provides meaningful insights into the use of Korean medicine as a safe, painless and efficient treatment for warts in pediatric patients.

키워드

과제정보

This study was supported by research funds from the Ministry of Health & Welfare through the Korea Health Industry Development Institute (KHIDI) and by the Guideline Center for Korean Medicine of the National Institute of Korean Medicine Development (HI16C0275).

참고문헌

  1. Bruggink SC, de Koning MN, Gussekloo J, Egberts FS, Schegget J, Feltkamp MCW et al. Cutaneous wart-associated HPV types: Prevalence and relation with patient characteristics. J Clin Virol 2012;55:250-255. https://doi.org/10.1016/j.jcv.2012.07.014
  2. de Koning MNC, Quint KD, Bruggink SC, Gussekloo J, Bavinck JN, Feltkamp MCW et al. High prevalence of cutaneous warts in elementary school children and ubiquitous presence of wart-associated human papillomavirus on clinically normal skin. Br J Dermatol 2015;172:196-201. https://doi.org/10.1111/bjd.13216
  3. Essa N, Saleh MA, Mostafa RM, Taha EA, Ismail TA. Prevalence and factors associated with warts in primary school children in Tema District, Sohag Governorate, Egypt. J Egypt Public Health Assoc 2019;94:6. https://doi.org/10.1186/s42506-018-0007-0
  4. Liu J, Li H, Yang F, Ren Y, Xia T, Zhao Z et al. Epidemiology and Clinical Profile of Cutaneous Warts in Chinese College Students: A Cross-Sectional and Follow-Up Study. Sci Rep 2018;8:15450. https://doi.org/10.1038/s41598-018-33511-x
  5. Bacelieri R, Johnson SM. Cutaneous warts: An evidence-based approach to therapy. Am Fam Physician 2005;72:647-652.
  6. Stender IM, Borgbjerg FM, Villumsen J, Lock-Andersen J, Wulf H-C. Pain induced by photodynamic therapy of warts. Photodermatol Photoimmunol Photomed 2006;22:304-309. https://doi.org/10.1111/j.1600-0781.2006.00259.x
  7. Gupta AK, Koren G, Shear NH. A double-blind, randomized, placebo-controlled trial of eutectic lidocaine/prilocaine cream 5% (EMLA)® for analgesia prior to cryotherapy of warts in children and adults. Pediatr Dermatol 1998;15:129-133. https://doi.org/10.1046/j.1525-1470.1998.1998015129.x
  8. Horn TD, Johnson SM, Helm RM, Roberson PK. Intralesional immunotherapy of warts with mumps, candida, and trichophyton skin test antigens: A single-blinded, randomized, and controlled trial. Arch Dermatol 2005;141:589-594. https://doi.org/10.1001/archderm.141.5.589
  9. Scott M, Nakagawa M, Moscicki AB. Cell-mediated immune response to human papillomavirus infection. Clin Diagn Lab Immunol 2001;8:209-220. https://doi.org/10.1128/CDLI.8.2.209-220.2001
  10. Stanley M. Immune responses to human papillomavirus. Vaccine 2006;24 Suppl 1:S16-22. https://doi.org/10.1016/j.vaccine.2005.09.002
  11. Xu K, Bi F. Wai ke zheng zhi quan shu. Shanghai (China): Shanghai gu ji chu ban she; 2002.
  12. Woo YE, Kim HK, Song BK, Lee EJ. Effects of Coicis Semen on the immune responses in the mouse. Korean J Orient Med 1996;2:269-288.
  13. Jeong HY, Cho CS. A clinical report of the effect of Uiin-San on a wart patient. J Intern Korean Med 2016;37:704-710. https://doi.org/10.22246/jikm.2016.37.5.704
  14. Lee GH, Kang SS, An WG, Lee YS, Kwon YK, Shin SW. Comparison of immune promotion effects of water-extracted AngelicaeGigantis, Rehmanniae Radix, Paeoniae Japonica and PolygoniMultiflori Radix. Korean J Orient PhysiolPathol 2006;20:1507-1515.
  15. Schlaeger JM, Stoffel CL, Bussell JL, Cai HY, Takayama M, Yajima H et al. Moxibustion for cephalic version of breech presentation. J Midwifery Womens Health 2018;63:309-322. https://doi.org/10.1111/jmwh.12752
  16. Yun Y, Shin S, Kim KS, Ko SG, Choi I. Three cases of cutaneous warts treated with moxibustion. Explore (NY) 2016;12:277-281. https://doi.org/10.1016/j.explore.2016.04.003
  17. Li X, Gao XH, Jin L, Wang Y, Hong Y, McHepange UO et al. Local hyperthermia could induce migrational maturation of langerhans cells in condyloma acuminatum. J Dermatol Sci 2009;54:121-123. https://doi.org/10.1016/j.jdermsci.2008.12.004
  18. Park SY, Won YS. Influences of previous pain experiences during dental treatment on dental fear. Korean J Health Serv Manag 2012;6:141-151. https://doi.org/10.12811/kshsm.2012.6.1.141