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갑상선기능항진증의 한약 치료에 대한 무작위 대조군 연구의 문헌 고찰

A Review of Randomized Controlled Trials of Herbal Medicine Treatment for Hyperthyroidism

  • 이희윤 (부산대학교 한방병원 한방부인과) ;
  • 황수인 (부산대학교 한방병원 한방부인과) ;
  • 박장경 (부산대학교 한방병원 한방부인과) ;
  • 윤영진 (부산대학교 한방병원 한방부인과)
  • Lee, Hee-Yoon (Dept. of Korean Medicine OB & GY, School of Korean Medicine, Pusan National University) ;
  • Hwang, Su-In (Dept. of Korean Medicine OB & GY, School of Korean Medicine, Pusan National University) ;
  • Park, Jang-Kyung (Dept. of Korean Medicine OB & GY, School of Korean Medicine, Pusan National University) ;
  • Yoon, Young-Jin (Dept. of Korean Medicine OB & GY, School of Korean Medicine, Pusan National University)
  • 투고 : 2021.07.16
  • 심사 : 2021.08.27
  • 발행 : 2021.08.27

초록

Objectives: The purpose of this study is to analyze the effectiveness and safety of herbal medicine treatment for treating hyperthyroidism. Methods: We searched for randomized controlled trials of Hyperthyroidism treated with herbal medicine, published from January 2016 to May 2021, through electronic database such as Pubmed, EMBASE, China Academic Journal (CAJ). Interventions and results of the selected clinical studies were analyzed. Results: The 25 randomized controlled trials were finally included according to the inclusion and exclusion criteria. Treatment group was treated with herbal medicine alone in 2 studies, and with herbal medicine and conventional medicine in 23 studies. Control group was treated with conventional medicine. Outcome measures are total efficacy rate, thyroid function test, Traditional Chinese medicine (TCM) syndrome scores, liver function test, recurrence rate, etc. Prunellae Spica (夏枯草) (60%) was the most frequently used herb in herbal medicine treatment. In all of 25 studies, treatment group was more effective and safer for hyperthyroidism than the control group. Conclusions: This study indicates that herbal medicine treatment alone or combined with conventional medicine treatment could be helpful in improving the therapeutic effect on hyperthyroidism and reducing side effects as well.

키워드

과제정보

본 연구는 2021년도 부산대학교병원 임상연구비 지원으로 이루어 졌음

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