Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Korean Guidelines for Diagnosis and Management of Interstitial Lung Diseases: Part 4. Cryptogenic Organizing Pneumonia

  • Choi, Sue In (Division of Respiratory, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Jung, Won Jai (Division of Respiratory, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine) ;
  • Lee, Eun Joo (Division of Respiratory, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine)
  • Received : 2021.02.07
  • Accepted : 2021.05.19
  • Published : 2021.07.31
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Abstract

Cryptogenic organizing pneumonia (COP) is a type of idiopathic interstitial pneumonia with an acute or subacute clinical course. Bilateral lung consolidations located in the subpleural area and bronchovascular bundle are the most common findings on chest high-resolution computed tomography. The pathologic manifestations include granulation tissue in the alveoli, alveolar ducts, and bronchioles. COP responds fairly well to glucocorticoid monotherapy with rapid clinical improvement, but recurrence is common. However, treatment with combined immunosuppressant agents is not recommended, even if the COP patient does not respond to glucocorticoid monotherapy with expert opinion.

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References

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