Journal of Convergence for Information Technology (융합정보논문지)

Convergence Society for SMB (중소기업융합학회)
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Subjective Skin Improvement and Safety of the Spicules-containing Cosmetics

스피큘을 함유한 화장품의 피부안전성 및 주관적 피부개선감 연구

  • Received : 2021.06.29
  • Accepted : 2021.08.20
  • Published : 2021.08.28
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Abstract

This study has purposes : evaluating how safe the skin is when applied with the Spicules-containing cosmetic, and whether Diamond-spicules is permeated into the skin and showed the efficacy of the active ingredients well. For these aims, women in their 30s and 60s were surveyed for skin irritation and changes after applying cosmetics to their skin for four weeks. As a result, Spicules-containing cosmetics were safer on the skin than general functional cosmetics, and in particular, in the case of cosmetics containing Diamond-spicules, statistically significant results (p<.001) were obtained in improvement of anti-wrinkle, firmness, moisturizing, whitening, alleviation of inflammation, and sensitivity. Thus, It has been proved Diamond-spicules containing functional active ingredients, not only as transdermal delivery system, but also can be used as multifunctional cosmetic material.

본 연구는 스피큘이 함유된 화장품을 피부에 적용하였을 때 안전한지를 평가하고, 기능성 활성 물질이 담지된 다이아몬드-스피큘이 경피흡수를 높이면서 피부에는 효율적으로 투과되어 그 효능이 잘 나타나는지 검토하는 데 목적을 두었다. 이를 위하여 30~60대 여성 30명을 대상으로 각 시험군에 따른 화장품을 4주간 피부에 적용하여 주관적으로 느끼는 피부 자극 및 피부 변화 여부를 설문지를 통하여 조사하였다. 그 결과 스피큘을 함유한 화장품이 일반 화장품과 비교하여 피부에 더 안전하였으며, 특히 다이아몬드-스피큘 함유화장품의 경우는 항주름, 탄력, 보습, 미백, 염증 완화 및 예민함 등이 시험 전과 비교하여 월등하게 개선되었다고 통계적으로도 유의미한 응답을 하였다(p<.001). 이로써 스피큘이 함유된 화장품이 피부에 안전하며, 기능성 활성 물질이 담지된 다이아몬드-스피큘이 경피전달시스템의 기능뿐 아니라 담지된 활성 물질이 피부에 효율적으로 투과될 수 있는 다기능성 화장품 소재로의 활용도 가능함을 확인하였다.

Keywords

References

  1. H. H. Kang. (2004). Well-being in cosmetics. J Soc. Cosmet. Scientists Korea, 30(3), 307-311.
  2. K. H. Kim, K. I. Ko, E. J. Kang, E. K. Yang, & S.N. Park. (2004). A research trend of natural product on well-being industry. J Soc. Cosmet. Scientists Korea, 30(3), 329-343.
  3. W.G. Cho. (2011). Transdermal delivery system of effective ingredients for cosmeceuticals. J Soc. Cosmet. Scientists Korea, 37(2), 97-112. DOI : 10.15230/SCSK.2011.37.2.097
  4. J. S. Kang, H. N. La, S. U. Bak, H. J. Eom, B. K. Lee & H. J. Shin. (2019). Development of dermal transduction epidermal growth factor (EGF) using a skin penetrating functional peptide. J. Soc. Cosmet. Scientists Korea, 45(2), 175-184. DOI : 10.15230/SCSK.2019.45.2.175
  5. M. M. Badran, J. Kuntsche & A. Fahr. (2009). Skin penetration enhancement by a microneedle device (DermarollerⓇ) in vitro: dependency on needle size and applied formulation. Eur. J. Pharm. Sci., 36(4-5), 511-523. DOI : 10.1016/j.ejps.2008.12.008
  6. J. H. Park, S. O. Choi, S. M. Seo, Y. B. Choy & M. R. Prausnitz. (2010). Microneedle roller for transdermal drug delivery. Eur. J. Pharm. Biopharm., 76(2), 282-289. DOI : 10.1016/j.ejpb.2010.07.001
  7. S. J. Kim. (2011). A study on transdermal drug delivery system with microneedle system in the field of skin care. KSBB Journal, 26(4), 277-282. https://doi.org/10.7841/ksbbj.2011.26.4.277
  8. K. C. Madison. (2003) Barrier function of the skin: "La raison d'ltre" of the epidermis. J. Invest. Dermatol., 121(2), 231-241. DOI : 10.1046/j.1523-1747.2003.12359.x
  9. G. S. Kim & S. M. Kang. (2017). The skin safety and effects of the fermented broth of lactobacillus rhamnosus for improving the neck skin. J. Kor. Soc. Cosm., 23(1), 101-114.
  10. H. Kalluri & A. K. Banga. (2011). Transdermal delivery of proteins. AAPS PharmSciTech, 12(1), 431-441. https://doi.org/10.1208/s12249-011-9601-6
  11. J. Y. Chung & H. S. Han. (2014). The recent trend of percutaneous absorption used in cosmetics. Asian J Beauty Cosmetol, 12(5), 597-605.
  12. G.S. Kim & S.M. Kang. (2016). The effects of the fermented broth of lactobacillus rhamnosus for improving the facial skin of middle-aged women as the skin barrier-recovering cosmetic material. J. Kor. Soc. Cosm., 22(5), 1004-1015.
  13. D.S. Han, G.S. Kim & S.M. Kang. (2020). The skin care effects and percutaneous absorptivity of the spicules-containing cosmetics. J. Kor. Soc. Cosm., 26(4), 886-896.
  14. D.S. Han. (2020). Skin Care Effects of the spicules-containing cosmetics. Doctoral dissertation, Konkuk university, Seoul.
  15. C. H. Lee & B. S. Choi. (2019). Improvement of facial acne on skin with 3% spicule. Asian J Beauty Cosmetol, 17(3), 397-410. https://doi.org/10.20402/ajbc.2019.0308
  16. H. S. Kim & Y. H. Choi. (2017). Comparative study on changes in skin condition according to peeling care techniques. Asian J Beauty Cosmetol, 16(1), 82-92.
  17. J. H. Yoo & S. H. Li. (2015). Effects of spicule and curcumin on an improvement in keratosis pilaris. Asian J Beauty Cosmetol, 13(6), 883-890.
  18. J. Kim. (1997). Perspective views of evaluation methods of cosmetic safety and efficacy. J. Kor. Soc. Cosm., 23(1), 159-184.
  19. KFDA. (2011). Guidelines for cosmetics risk assessment. (Online). https://www.mfds.go.kr
  20. S. H. Moon, S. S. Han, Y. H. Kim, W. K. Yoo & K. H. Kim. (2018). Cosmetic safety awareness: a comparison between general consumers and skin care workers. J Invest Cosmetol, 14(3), 343-350. DOI : 10.15810/jic.2018.14.3.010
  21. M. N. Lee, M. H. Jang & I. H. Lee. (2014). The status of skin condition and using of cosmetic for 50's women. JKAIS, 15(12), 7005-7011. DOI : 10.5762/KAIS.2014.15.12.7005
  22. Y. K. Yoo, M. S. Lee, K. H. Choi, G. T. Lee & K. K. Lee. (2015). The efficacy and safety test of new moisturizing cream for dry skin condition and itch relief. Asian J Beauty Cosmetol, 13(1), 49-57.
  23. S. I. Jang, S. M. Lee, B. R. Paik, J. Han, E. J. Kim & H. K. Lee. (2017). A study on skin permeability and skin whitening effect of high pressure emulsification processed cosmetic. J. Soc. Cosmet. Sci. Korea, 43(3), 189-194. DOI : 10.15230/SCSK.2017.43.3.189
  24. J. Y. Joo & S. H. Lee. (2016). The effects of interest level in appearance of korean middle aged women on purchasing pattern of cosmetic products. KSDC Journal, 22(1), 401-410.
  25. E. K. Sim & K. R. Kim. (2008). Consumer's preference and determinants of purchase of cosmeceutical products. J. Kor. Soc. Cosm., 14(4), 1264-1279.
  26. D. S. Han. (2020). Cosmetic composition for skin wrinkle improvement and whitening facial skin. KR patent No 1020200147498 Daejeon : Korean Intellectual Property Office
  27. D. S. Han. (2020). Functional cosmetic composition for improving skin wrinkles and elasticity. KR patent No 1020200147499 Daejeon : Korean Intellectual Property Office
  28. D. S. Han. (2020). Functional cosmetic composition for skin moisturizing and soothing. KR patent No 1020200147500 Daejeon : Korean Intellectual Property Office
  29. Korea Consumer Agency. (2003). Cosmetic safety survey. 2002 Consumer Damage Information Analysis and Safety Status Investigation, pp. 92-115.
  30. C. E. Lance, M. M. Butts & L. C. Michels. (2006). The sources of four commonly reported cut off criteria : what did they really say?. Organizational Research Methods, 9(2), 202-220. DOI : 10.1177/1094428105284919
  31. Y. E. Choi & H. S. Ahn (2012). The effect of microneedle therapy system to improve the facial skin conditions for mid-aged women. Asian J Beauty Cosmetol, 10(3), 611-618.
  32. H. J. Lee, H. S. Ahn & H. S. Bae. (2012). Antioxidant status of serum by the wellness index of the skin in the middle aged women. Asian J Beauty Cosmetol, 10(1), 15-23.
  33. M. H. Kim. (2021). The effects of aestheticians' professional care on the facial skin of middle-aged women in their 40s. J. Int. Soc. Heal. Beau., 15(1), 41-50. DOI : 10.35131/ishb.2021.15.1.4
  34. H. S. Kim & S. H. You. (2017). A study on skin change of women in their 40s-50s according to types of peeling. J. Kor. Soc. Cosm., 23(6), 1245-1253.
  35. S. K. Kang, S. Y. Ryu & J. Park (2005). Condition of facial skin by non-invasive measurement and lipid.moisture type of the facial skin by subjective self-consciousness in some middle-aged women. J. Soc. Cosmet. Scientists Korea, 31(3), 279-283.
  36. S. H. Park & S. O. Noh. (2014). Effect of high frequency therapy on middle-aged wonmen's skin conditions. JKAIS, 2014(2), 796-799.
  37. J. M. Lee. (2020). Awareness of facial skin care for particulate matter and needs analysis for anti-pollution. master's thesis, Youngsan University, Busan.
  38. S. K. Seo, C. S. Ku, B. M. Son, S. G. Lee, E. M. Kang, M. Kim, J. H. Hong, S. Kim & M. S. Shin. (2016). Anti-pollution capacity of mixtures of anemarrhena asphodeloides root extract, β-glucan and poly-γ-glutamic acid from stimulation with particulate matter. J Invest Cosmetol, 12(4), 313-322. DOI : 10.15810/jic.2016.12.4.004
  39. J. A. Hyun, J. H. Lee, E. B. Kang, H. J. Kim, D. I. Kim, G. E. Park, K. S. Kwak & B. J. An. (2020). Validation of pharmacological activity and anti-pollution effect of ethanol extract of azadirachta indica leaf. Korean J. Food Preserv., 27(3), 393-406. DOI : 10.11002/kjfp.2020.27.3.393