Therapeutic Science for Rehabilitation (재활치료과학)

Korean Society of Neurological Occupational Therapy (대한신경계작업치료학회)
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A Study on the Effect of Virtual Reality Intervention on Cognitive Function in Individuals With Stroke Through Meta-analysis

메타분석을 통한 뇌졸중 환자의 인지기능에 대한 가상현실 중재 효과 연구

  • Kwon, Jae Sung (Dept. of Occupational Therapy, College of Health Science, Cheongju University)
  • 권재성 (청주대학교 보건의료과학대학 작업치료학과)
  • Received : 2021.04.25
  • Accepted : 2021.06.17
  • Published : 2021.08.31
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Abstract

Objective : The purpose of this study was to verify the effect of virtual reality interventions (VRIs) on cognitive function in individuals with stroke through a systematic literature review and meta-analysis. Methods : We reviewed randomized controlled trials (RCTs) the last 10 years using academic databases. PubMed, MEDLINE, and CINAHL were used for international studies, and DBpia, KISS, Kyoboscholar, and e-article were used for Korean studies. For the quantitative meta-analysis, subgroups of outcomes were classified into general cognitive function (G-CF), attention and memory (A&M), and executive function (EF). Results : Nine RCTs were analyzed. The total number of participants was 271 (140 in the experimental group). The effect size (Cohen's d) was estimated using a random effects model. The effect sizes of the outcome subgroups of were as follows: small to medium for G-CF (d=0.422; 95% CI: 0.101~0.742; p=0.010), small for A&M (d=0.249; 95% CI: -0.107~0.605; p=0.170), and medium for EF (d=0.666; 95% CI: 0.136~1.195; p=0.014). Conclusion : Considering the various stimuli provided by the virtual environment and the results from available research, virtual reality should be applied to interventions for integrated cognitive functions. In addition, it would be appropriate to be used as an additional intervention to traditional cognitive rehabilitation for stroke.

목적 : 본 연구에서는 뇌졸중 환자의 손상된 인지기능 회복을 위한 가상현실 중재의 효과를 체계적인 문헌고찰과 메타분석을 통하여 검증하고자 하였다. 연구방법 : 체계적 문헌고찰을 위하여 최근 10년 동안의 국내·외 무작위 대조 임상시험 연구들을 대상으로 조사하였다. 검색을 위한 학술 데이터베이스로는, 영어로 작성된 연구의 검색을 위해 PubMed와 MEDLINE, CINAHL을 사용하였고, 국문으로 작성된 연구의 검색을 위해서는 DBpia와 한국학술정보, 스콜라 학지사·교보문고, 학술교육원을 사용하였다. 정보의 추출은 PICO 방식으로 시행하였다. 계량적 메타분석을 위하여, 결과변인의 하위그룹을 전반적인 인지기능, 집중력과 기억력, 실행기능으로 분류하여 결과변인을 합성하였다. 결과 : 최종 9편의 무작위 대조 임상시험이 선정되었고, 참여대상자의 총인원은 실험군이 140명, 대조군이 131명이었다. 효과크기는 랜덤효과모델로 산출하였다. 하위그룹들에 대한 가상현실 중재의 효과크기는 전반적인 인지기능이 0.422(95% CI: 0.101~0.742; p=0.010)로 중간효과크기에 가까웠고, 집중력과 기억력이 0.249(95% CI: -0.107~0.605; p=0.170)로 작은효과크기, 실행기능은 0.666(95% CI: 0.136~1.195; p=0.014)으로 중간효과크기를 나타내었다. 결론 : 가상현실 환경의 다양한 자극과 본 연구의 결과를 고려할 때, 가상현실 중재는 통합적인 인지기능에 대한 중재에 적용되어야 할 것이다. 또한 전통적인 뇌졸중 인지재활 중재와 더불어 추가적인 중재로 활용되는 것이 적절할 것이다.

Keywords

Acknowledgement

이 연구는 2019-2021학년도에 청주대학교 보건의 료과학연구소가 지원한 학술연구조성비(특별연구과제)에 의해 연구되었음

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