Korean Journal of Agricultural Science (농업과학연구)

  • 제48권3호
  • /
  • Pages.447-454
  • /
  • 2021
  • /
  • 2466-2402(pISSN)
  • /
  • 2466-2410(eISSN)
Institute of Agricultural Science, CNU (충남대학교 농업과학연구소)
권호 표지
DOI QR코드

DOI QR Code

Effects of different copper sources (inorganic and organic) on the growth performance, fecal excretion, intestinal morphology, and health in growing pigs

  • Kim, Minji (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Jung, Hyunjung (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Seong, Pil-Nam (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Jeong, Jin Young (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Baek, Youl-Chang (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Park, Seol Hwa (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Ryu, Chae Hwa (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Ki Hyun (Animal Welfare Team, National Institute of Animal Science, Rural Development Administration) ;
  • Chun, Ju Lan (Animal Welfare Team, National Institute of Animal Science, Rural Development Administration) ;
  • Oh, Sang-Ik (Division of Animal Disease & Health, National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Byeonghyeon (Animal Nutrition & Physiology Team, National Institute of Animal Science, Rural Development Administration)
  • 투고 : 2021.05.24
  • 심사 : 2021.06.30
  • 발행 : 2021.09.01
Download PDF
⟨ Previous Next ⟩

초록

This study was conducted to evaluate the effects of different copper sources (inorganic and organic) on the growth performance, fecal copper excretion, intestinal morphology, and health in growing pigs. A total of 40 growing pigs (30.22 ± 1.92 kg) were randomly assigned to 5 dietary treatments: a basal control diet (CON), 4 experimental diets supplemented with either copper sulfate (CuSO4), Cu-glycine complex (CuGly), Cu-amino acid complex (CuAA), or Cu-hydroxy-4-methylthio butanoate chelate complex (CuHMB) at 100 ppm, respectively. At the end of the study (28 days), fecal and blood samples were collected, and the pigs were slaughtered to determine the intestinal morphology. During the 28 days of the experimental period, pigs fed the inorganic and organic copper showed a higher average daily gain (p < 0.01) and gain feed ratio (p < 0.01). There were no differences in mineral concentrations of the serum; however, the copper concentration of the feces was lower (p < 0.01) in the CuAA and CuHMB groups. The intestinal morphology and blood profiles did not significantly differ between the groups. In conclusion, the organic copper sources (CuAA and CuHMB) can be used as a growth promoter to replace the CuSO4 without any negative effects on health in growing pigs and to reduce fecal copper excretion.

키워드

과제정보

본 연구는 농촌진흥청 연구사업(세부과제번호: PJ01493601)의 지원과 2021년도 농촌진흥청 국립축산과학원 전문연구원 과정 지원사업에 의해 수행되었습니다.

참고문헌

  1. Carpenter CB, Woodworth JC, Derouchey JM, Tokach MD, Goodband RD, Dritz SS, Dritz SS, Wu F, Usry JL. 2019. Effects of increasing copper from tri-basic copper chloride or a copper-methionine chelate on growth performance of nursery pigs. Translational Animal Science 3:58-64.
  2. Chabaev MG, Nekrasov RV, Strekozov NI, Tsis EY, Klementyev MI. 2020. Effects of different levels and forms of chelated metal proteinates on productive performance and metabolic processes in fattening young pigs. Russian Agricultural Sciences 46:161-166. https://doi.org/10.3103/S1068367420020032
  3. Coble KF, Burnett DD, DeRouchey JM, Tokach MD, Gonzalez JM, Wu F, Dritz SS, Goodband RD, Woodworth JC, Pluske JR. 2018. Effect of diet type and added copper on growth performance, carcass characteristics, energy digestibility, gut morphology, and mucosal mRNA expression of finishing pigs. Journal of Animal Science 96:3288-3301. https://doi.org/10.1093/jas/sky196
  4. Espinosa CD, Stein HH. 2021. Digestibility and metabolism of copper in diets for pigs and influence of dietary copper on growth performance, intestinal health, and overall immune status: a review. Journal of Animal Science and Biotechnology 12:1-12. https://doi.org/10.1186/s40104-020-00531-5
  5. Fry RS, Ashwell MS, Lloyd KE, O'Nan AT, Flowers WL, Stewart KR, Spears JW. 2012. Amount and source of dietary copper affects small intestine morphology, duodenal lipid peroxidation, hepatic oxidative stress, and mRNA expression of hepatic copper regulatory proteins in weanling pigs. Journal of Animal Science 90:3112-3119. https://doi.org/10.2527/jas.2011-4403
  6. Huang Y, Yoo JS, Kim HJ, Wang Y, Chen YJ, Cho JH, Kim IH. 2010a. The effects of different copper (inorganic and organic) and energy (tallow and glycerol) sources on growth performance, nutrient digestibility, and fecal excretion profiles in growing pigs. Asian-Australasian Journal of Animal Sciences 23:573-579. https://doi.org/10.5713/ajas.2010.80436
  7. Huang Y, Zhou TX, Lee JH, Jang HD, Park JC, Kim IH. 2010b. Effect of dietary copper sources (cupric sulfate and cupric methionate) and concentrations on performance and fecal characteristics in growing pigs. Asian-Australasian Journal of Animal Sciences 23:757-761. https://doi.org/10.5713/ajas.2010.80437
  8. Hyder MA, Hasan M, Mohieldein AH. 2013. Comparative levels of ALT, AST, ALP and GGT in Liver associated diseases. European Journal of Experimental Biology 3:280-284.
  9. Lee DS, Lee JB, Lee MY, Joo RN, Lee KS, Min SW, Hong BD, Chung DY. 2016. Chemical properties of liquid swine manure for fermentation step in public livestock recycling center. Korean Journal of Agricultural Science 43:424-431. [in Korean] https://doi.org/10.7744/kjoas.20160045
  10. Lee SH, Choi SC, Chae BJ, Acda SP, Han YK. 2001. Effects of feeding different chelated copper and zinc sources on growth performance and fecal excretions of weanling pigs. Asian-Australasian Journal of Animal Sciences 14:1616-1620. https://doi.org/10.5713/ajas.2001.1616
  11. Liao P, Li M, Li Y, Tan X, Zhao F, Shu X, Yin Y. 2017. Effects of dietary supplementation with cupreous N-carbamylglutamate (NCG) chelate and copper sulfate on growth performance, serum biochemical profile and immune response, tissue mineral levels and fecal excretion of mineral in weaning piglets. Food and Agricultural Immunology 28:1315-1329. https://doi.org/10.1080/09540105.2017.1339668
  12. Liao P, Shu X, Tang M, Tan B, Yin Y. 2018. Effect of dietary copper source (inorganic vs. chelated) on immune response, mineral status, and fecal mineral excretion in nursery piglets. Food and Agricultural Immunology 29:548-563. https://doi.org/10.1080/09540105.2017.1416068
  13. Lin G, Guo Y, Liu B, Wang R, Su X, Yu D, He P. 2020. Optimal dietary copper requirements and relative bioavailability for weanling pigs fed either copper proteinate or tribasic copper chloride. Journal of Animal Science and Biotechnology 11:1-15. https://doi.org/10.1186/s40104-019-0409-7
  14. Liu Y, Ma YL, Zhao JM, Vazquez-Anon M, Stein HH. 2014. Digestibility and retention of zinc, copper, manganese, iron, calcium, and phosphorus in pigs fed diets containing inorganic or organic minerals. Journal of Animal Science 92:3407-3415. https://doi.org/10.2527/jas.2013-7080
  15. NIAS (National Institute of Animal Science). 2017. Korean feeding standard for swine. NIAS, RDA, Wanju, Korea. [in Korean]
  16. Pluske JR, Pethick DW, Hopwood DE, Hampson DJ. 2002. Nutritional influences on some major enteric bacterial diseases of pig. Nutrition Research Reviews 15:333-371. https://doi.org/10.1079/NRR200242
  17. SAS (Statistical Analysis System). 2009. SAS user's guide. Version 9.4. SAS Institute Inc., Cary, NC, USA.
  18. Shurson GC, Ku PK, Waxler GL, Yokoyama MT, Miller ER. 1990. Physiological relationships between microbiological status and dietary copper levels in the pig. Journal of Animal Science 68:1061-1071. https://doi.org/10.2527/1990.6841061x
  19. Yenice E, Mizrak C, Gultekin M, Atik Z, Tunca M. 2015. Effects of organic and inorganic forms of manganese, zinc, copper, and chromium on bioavailability of these minerals and calcium in late-phase laying hens. Biological Trace Element Research 167:300-307. https://doi.org/10.1007/s12011-015-0313-8
  20. Zhao J, Allee G, Gerlemann G, Ma L, Gracia MI, Parker D, Vazquez-Anon M, Harrell RJ. 2014. Effects of a chelated copper as growth promoter on performance and carcass traits in pigs. Asian-Australasian Journal of Animal Sciences 27:965-973. https://doi.org/10.5713/ajas.2013.13416
  21. Zhao J, Harper AF, Estienne MJ, Webb KE, McElroy AP, Denbow DM. 2007. Growth performance and intestinal morphology responses in early weaned pigs to supplementation of antibiotic-free diets with an organic copper complex and spray-dried plasma protein in sanitary and nonsanitary environments. Journal of Animal Science 85:1302-1310. https://doi.org/10.2527/jas.2006-434