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A Case Report of Non-Motor Symptoms Evaluated Using the Non-Motor Symptom Scale in a Patient with Secondary Parkinsonism Presumed to be Probable Lewy Body Dementia and Improved with Combined Treatment with Herbal Medicine and Acupuncture

루이소체 치매로 추정되는 이차성 파킨슨증 환자의 Non-Motor Symptom Scale(NMSS)로 평가한 비운동성 증상을 한약과 침의 복합치료로 호전시킨 증례보고 1례

  • Roh, Min-yeong (Dept. of Internal Korean Medicine, Dong-Shin Korean Medicine Hospital) ;
  • Lee, Ji-hyun (Dept. of Internal Korean Medicine, Dong-Shin Korean Medicine Hospital) ;
  • Han, Yang-hee (Dept. of Internal Korean Medicine, Dong-Shin Korean Medicine Hospital) ;
  • Leem, Jung-tae (Research Center of Traditional Korean Medicine, Wonkwang University)
  • 노민영 (목동동신한방병원 한방내과) ;
  • 이지현 (목동동신한방병원 한방내과) ;
  • 한양희 (목동동신한방병원 한방내과) ;
  • 임정태 (원광대학교 전통의학연구소)
  • Received : 2021.09.03
  • Accepted : 2021.11.01
  • Published : 2021.10.30

Abstract

Parkinson's syndrome is a degenerative brain disease that presents characteristic motor symptoms of tremor, rigidity, and gait disturbance. In addition to these motor symptoms, Parkinson's syndrome also presents non-motor symptoms (NMSs) such as sleep disturbance and cognitive decline. NMSs reduce patient's quality of life and psychosocial functioning and cause economic burden on the patient, so appropriate evaluation and treatment are required. Lewy body dementia is one of the several diseases belonging to Parkinson's syndrome. Its symptoms such as cognitive function, memory impairment, and hallucinations occur with Parkinsonism. Although drug therapy is being used with drug treatment to treat non-motor symptoms, it has limitations such as side effects, which stimulated interest in other complementary treatment methods such as oriental medicine treatment, dance, and yoga. The patient in this case complained of tremor in the right upper extremity, muscle hypertension and pain, and persistent vision, memory, and cognitive decline. The patient was diagnosed with probable Lewy body dementia. The patient was hospitalized for 4 months and received acupuncture and herbal medicines. After treatment, the patient's NMS scale scores decreased from 90 to 63, and the Unified Parkinson's Disease Rating Scale scores (summed I, II, and III) decreased from 17 points to 8 points. The Beck Depression Inventory score decreased from 22 points to 13 points. In addition, the patient's subjective evaluation revealed improvement. In this case, a patient diagnosed with probable Lewy body dementia who did not respond to the standard treatment and did not want to take medications showed improvement in not only motor symptoms but also NMSs after integrative Korean medicine treatment.

Keywords

Acknowledgement

이 성과는 정부(과학기술정보통신부)의 재원으로 한국 연구재단의 지원을 받아 수행된 연구임(NRF-2019R1F1A1059310)

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