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Subcutaneous Sarcoidosis of the Distal Lower Leg in a Middle-Aged Woman Associated with Pulmonary Sarcoidosis: a Case Report

  • Lea, Winnah Wu-in (Department of Radiology, Guro Hospital, Korea University College of Medicine) ;
  • Hong, Suk-Joo (Department of Radiology, Guro Hospital, Korea University College of Medicine) ;
  • Kang, Woo-Young (Department of Radiology, Guro Hospital, Korea University College of Medicine) ;
  • Kang, Eun-Young (Department of Radiology, Guro Hospital, Korea University College of Medicine) ;
  • Jeon, Tae-Sung (Department of Pathology, Guro Hospital, Korea University College of Medicine)
  • Received : 2021.08.22
  • Accepted : 2021.09.30
  • Published : 2022.03.30

Abstract

Sarcoidosis is a systemic disease of unknown etiology that can involve almost any organ systems, characterized by the presence of non-caseating granulomas in affected organs. Typically, the lungs and mediastinal lymph nodes are the most-affected sites, with cutaneous manifestations being the second. Subcutaneous nodules are a rare manifestation of cutaneous sarcoidosis, and it is even rarer for subcutaneous sarcoidosis to be associated with pulmonary sarcoidosis. Here, we present a case of subcutaneous sarcoidosis of the distal lower leg associated with pulmonary sarcoidosis.

Keywords

References

  1. Thomas KW, Hunninghake GW. Sarcoidosis. JAMA 2003;289:3300-3303 https://doi.org/10.1001/jama.289.24.3300
  2. Marcoval J, Mana J, Rubio M. Specific cutaneous lesions in patients with systemic sarcoidosis: relationship to severity and chronicity of disease. Clin Exp Dermatol 2011;36:739-744 https://doi.org/10.1111/j.1365-2230.2011.04128.x
  3. Zendah I, Badri T, Salah EB, Ghedira H. Subcutaneous sarcoidosis with thoracic involvement: a very rare presentation of the disease. Respir Med Case Rep 2020;30:101041 https://doi.org/10.1016/j.rmcr.2020.101041
  4. Mehrzad R, Festa J, Bhatt R. Subcutaneous sarcoidosis of the upper and lower extremities: a case report and review of the literature. World J Clin Cases 2019;7:2505-2512 https://doi.org/10.12998/wjcc.v7.i17.2505
  5. Shinozaki T, Watanabe H, Aoki J, Fukuda T, Shirakura K, Takagishi K. Imaging features of subcutaneous sarcoidosis. Skeletal Radiol 1998;27:359-364 https://doi.org/10.1007/s002560050398
  6. Ahmed I, Harshad SR. Subcutaneous sarcoidosis: is it a specific subset of cutaneous sarcoidosis frequently associated with systemic disease? J Am Acad Dermatol 2006;54:55-60 https://doi.org/10.1016/j.jaad.2005.10.001
  7. Choi KH, Choi YS, Kim BS, et al. A nodular type of subcutaneous sarcoidosis: a case report. J Korean Soc Radiol 2009;60:47-50 https://doi.org/10.3348/jksr.2009.60.1.47
  8. Fujimoto H, Ikeda M, Shimofusa R, Terauchi M, Eguchi M. Sarcoidosis breaching the fascia and mimicking a sarcoma. Skeletal Radiol 2002;31:706-708 https://doi.org/10.1007/s00256-002-0548-2
  9. Lim JH, Shim J-C, Yoon B-H, et al. Rare form of rheumatoid nodule around ischial tuberosity mimicking ischiogluteal bursitis. Investig Magn Reson Imaging 2017;21:97-101 https://doi.org/10.13104/imri.2017.21.2.97
  10. Beaman FD, Kransdorf MJ, Andrews TR, Murphey MD, Arcara LK, Keeling JH. Superficial soft-tissue masses: analysis, diagnosis, and differential considerations. Radiographics 2007;27:509-523 https://doi.org/10.1148/rg.272065082