대한의생명과학회지 (Biomedical Science Letters)

  • 제28권4호
  • /
  • Pages.322-326
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  • 2022
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  • 1738-3226(pISSN)
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  • 2288-7415(eISSN)
대한의생명과학회 (The Korean Society for Biomedical Laboratory Sciences)
권호 표지
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Quantitative Analysis of Chemical Components of Hydrolysate from Silkworm Fed with Cudrania tricuspidata Leaves

  • Jae Hwan, Choi (RMI Center, Nutricare Co., Ltd.) ;
  • Min Ji, Nam (RMI Center, Nutricare Co., Ltd.) ;
  • Ga Hee, Ryu (RMI Center, Nutricare Co., Ltd.) ;
  • Jeong Wook, Jeon (R&D Center, Nutricare Co., Ltd.) ;
  • Sung Seob, Yun (RMI Center, Nutricare Co., Ltd.)
  • 투고 : 2022.11.29
  • 심사 : 2022.12.19
  • 발행 : 2022.12.31
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초록

The purpose of this study was to develop hydrolysate from silkworm (Cudrania Silkworm Fibroin Peptide; CSFP), a food containing components for improving blood vessel health. In general, Cudrania tricuspidata leaves contain about 5 times more rutin and 25 times more dihydroquercetin than mulberry leaves. 1-Deoxynojirimycine (1-DNJ), dihydroquercetin and rutin inhibit the activity of carbohydrate-digesting enzymes, inhibit blood lipid peroxidation, and regulate insulin secretion, which helps blood vessels to be healthy. When the diet-controlled silkworm was enzymatically hydrolyzed, it was confirmed that rutin content was about 8 times higher than that of the in general silkworm as a control. In the silkworm hydrolysate, CSFP, developed as a final food material, the active ingredients were 65 mg/kg for rutin, 3,328 mg/kg for DNJ, 0.43 mg/kg for dihydroquercetin, and 82,624 mg/kg for total polyphenol, which was confirmed through LC-MS/MS analysis. In conclusion, it was found that silkworms fed with C. tricuspidata leaves as a diet had more active components that can help control blood sugar and improve blood vessel health than silkworms fed with mulberry leaves.

키워드

과제정보

This work was supported by a grant of the Agricultural Technology Commercialization Support Project through the Rural Development Administration, Republic of Korea (Project number PJ01693001).

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