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Cemento-osseous dysplasia: clinical presentation and symptoms

  • Nam, Inhye (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Ryu, Jihye (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Shin, Sang-Hun (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Kim, Yong-Deok (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University) ;
  • Lee, Jae-Yeol (Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University)
  • Received : 2021.07.19
  • Accepted : 2021.10.12
  • Published : 2022.04.30

Abstract

Objectives: The purpose of this study was to evaluate risk factors and symptoms in cemento-osseous dysplasia (COD) patients. Materials and Methods: In this study, 62 patients who were diagnosed histologically with COD were investigated from 2010 to 2020 at the author's institution. We compared clinical and radiological characteristics of symptomatic and asymptomatic patients. The factors were sex, age, lesion size, site, radiologic stage of lesion, apical involvement, sign of infection, and history of tooth extraction. Statistical analysis was performed using Fisher's exact test and the chi-square test. Results: COD was more prevalent in female patients. With the exception of three cases, all were focal COD. The majority of patients presented with symptoms when the lesion was smaller than 1.5 cm in size. Symptoms were observed when the apex of the tooth was included in the lesion or there was a local infection around the lesion. The history of tooth extraction and previous endodontic treatment were evaluated, and history was not a significant predictor for the onset of symptoms. Conclusion: In this study, risk factors associated with symptomatic patients were size of lesion, apical involvement, and local infection.

Keywords

Acknowledgement

This work was supported by a 2-Year Research Grant of Pusan National University.

References

  1. Alsufyani NA, Lam EW. Osseous (cemento-osseous) dysplasia of the jaws: clinical and radiographic analysis. J Can Dent Assoc 2011;77:b70.
  2. Mainville GN, Turgeon DP, Kauzman A. Diagnosis and management of benign fibro-osseous lesions of the jaws: a current review for the dental clinician. Oral Dis 2017;23:440-50. https://doi.org/10.1111/odi.12531
  3. MacDonald DS. Classification and nomenclature of fibro-osseous lesions. Oral Surg Oral Med Oral Pathol Oral Radiol 2021;131:385-9. https://doi.org/10.1016/j.oooo.2020.12.004
  4. de Noronha Santos Netto J, Machado Cerri J, Miranda AM, Pires FR. Benign fibro-osseous lesions: clinicopathologic features from 143 cases diagnosed in an oral diagnosis setting. Oral Surg Oral Med Oral Pathol Oral Radiol 2013;115:e56-65. https://doi.org/10.1016/j.oooo.2012.05.022
  5. Kim NK, Kim HS, Kim J, Nam W, Cha IH, Kim HJ. Florid cemento-osseous dysplasia: a report of two cases. J Korean Assoc Oral Maxillofac Surg 2011;37:515-9. https://doi.org/10.5125/jkaoms.2011.37.6.515
  6. Nelson BL, Phillips BJ. Benign fibro-osseous lesions of the head and neck. Head Neck Pathol 2019;13:466-75. https://doi.org/10.1007/s12105-018-0992-5
  7. Brody A, Zalatnai A, Csomo K, Belik A, Dobo-Nagy C. Difficulties in the diagnosis of periapical translucencies and in the classification of cemento-osseous dysplasia. BMC Oral Health 2019;19:139. https://doi.org/10.1186/s12903-019-0843-0
  8. Kato CN, Barra SG, Pereira MJ, Gomes LT, Amaral TM, Abreu LG, et al. Mandibular radiomorphometric parameters of women with cemento-osseous dysplasia. Dentomaxillofac Radiol 2020;49:20190359. https://doi.org/10.1259/dmfr.20190359
  9. Mufeed A, Mangalath U, George A, Hafiz A. Infected florid osseous dysplasia: clinical and imaging follow-up. BMJ Case Rep 2015;2015:bcr2014209099. https://doi.org/10.1136/bcr-2014-209099
  10. Olgac V, Sinanoglu A, Selvi F, Soluk-Tekkesin M. A clinicopathologic analysis of 135 cases of cemento-osseous dysplasia: to operate or not to operate? J Stomatol Oral Maxillofac Surg 2021;122:278-82. https://doi.org/10.1016/j.jormas.2020.06.002
  11. Kawai T, Hiranuma H, Kishino M, Jikko A, Sakuda M. Cemento-osseous dysplasia of the jaws in 54 Japanese patients: a radiographic study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;87:107-14. https://doi.org/10.1016/s1079-2104(99)70303-3
  12. Cavalcanti PHP, Nascimento EHL, Pontual MLDA, Pontual ADA, Marcelos PGCL, Perez DEDC, et al. Cemento-osseous dysplasias: imaging features based on cone beam computed tomography scans. Braz Dent J 2018;29:99-104. https://doi.org/10.1590/0103-6440201801621
  13. Gumru B, Akkitap MP, Deveci S, Idman E. A retrospective cone beam computed tomography analysis of cemento-osseous dysplasia. J Dent Sci 2021;16:1154-61. https://doi.org/10.1016/j.jds.2021.03.009
  14. Shibata N, Inamoto K, Naitoh M, Ariji E. Clinical assessment of cemento-osseous dysplasia based on three-dimensional diagnostic imaging: a case report. Aust Endod J 2021;47:105-12. https://doi.org/10.1111/aej.12488
  15. Su L, Weathers DR, Waldron CA. Distinguishing features of focal cemento-osseous dysplasia and cemento-ossifying fibromas. II. A clinical and radiologic spectrum of 316 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1997;84:540-9. https://doi.org/10.1016/s1079-2104(97)90271-7
  16. Ravikumar SS, Vasupradha G, Menaka TR, Sankar SP. Focal cemento-osseous dysplasia. J Oral Maxillofac Pathol 2020;24(Suppl 1):S19-22. https://doi.org/10.4103/jomfp.JOMFP_209_19
  17. Min CK, Koh KJ, Kim KA. Recurrent symptomatic cemento-osseous dysplasia: a case report. Imaging Sci Dent 2018;48:131-7. https://doi.org/10.5624/isd.2018.48.2.131
  18. Kato CNAO, de Arruda JAA, Mendes PA, Neiva IM, Abreu LG, Moreno A, et al. Infected cemento-osseous dysplasia: analysis of 66 cases and literature review. Head Neck Pathol 2020;14:173-82. https://doi.org/10.1007/s12105-019-01037-x
  19. Gunhan O, Kahraman D, Yalcin UK. The possible pathogenesis of cemento-osseous dysplasia: a case series and discussion. Adv Oral Maxillofac Surg 2021;3:100105. https://doi.org/10.1016/j.adoms.2021.100105
  20. Ray JM, Triplett RG. What is the role of biofilms in severe head and neck infections? Oral Maxillofac Surg Clin North Am 2011;23:497-505. https://doi.org/10.1016/j.coms.2011.07.002