DOI QR코드

DOI QR Code

Guideline for the Management of Neonates Born to Mothers With COVID-19

코로나19 감염 산모에서 출생한 신생아 관리 지침

  • Jae Hong Choi (Department of Pediatrics, Jeju National University College of Medicine) ;
  • Soo-Han Choi (Department of Pediatrics, Pusan National University School of Medicine) ;
  • Do-Hyun Kim (Department of Pediatrics, Dongguk University Ilsan Hospital) ;
  • Yong-Sung Choi (Department of Pediatrics, Kyung Hee University College of Medicine) ;
  • Ki Wook Yun (Department of Pediatrics, Seoul National University College of Medicine)
  • 최재홍 (제주대학교 의과대학 소아청소년과) ;
  • 최수한 (부산대학교 의과대학 소아청소년과) ;
  • 김도현 (동국대학교 일산병원 소아청소년과) ;
  • 최용성 (경희대학교 의과대학 소아청소년과) ;
  • 윤기욱 (서울대학교 의과대학 소아청소년과)
  • Received : 2022.09.29
  • Accepted : 2022.12.14
  • Published : 2022.12.25

Abstract

For the extended duration of the coronavirus disease 2019 (COVID-19) pandemic, reports emerged that mother-to-child transmission rates were low. However, the pandemic protocols including strict isolation, testing for severe acute respiratory syndrome coronavirus 2, and negative pressure isolation remained in Korea. Recently, the guideline for the management of neonates born to mothers with COVID-19 have been revised based on guidelines in other countries. Here, we introduce this newly developed guideline and review the foreign guidelines that were used for reference.

장기화된 코로나19의 유행으로 많은 임산부들이 분만에 임박하여 감염되는 사례들이 많아진 반면, 이런 상황에서 출생하는 신생아들을 처치 및 검사에 대한 국내 권고 사항은 코로나19 유행 초기에 만들어져 진료 현장에서 어려움이 많았다. 다행히 최근에 축적된 자료와 외국의 최신 지침을 반영한 국내 권고 사항이 개정 발표되어 이를 소개하게 되었다. 대표적인 변화로는 코로나19 확진 산모에게 출생한 신생아의 처치 및 검사가 반드시 음압 격리 시설 내에서 이루어질 필요 없이 적절한 보호장구를 착용한 상태에서 신생아실에서 이루어질 수 있도록 하였다. 또한 코로나19 검사도 생후 48-72시간에 1회 시행할 것을 권고하였으며, 모자 동실을 할 경우에는 증상 없는 건강한 신생아라면 검사 없이 경과 관찰할 수 있도록 하였다. 입원이 필요한 경우에는 기존 권고 사항과 같이 생후 24시간, 48시간 째에 각각 두 번 검사를 시행하도록 하였다. 개정된 권고 사항이 코로나19 확진 산모와 신생아의 진료에 유연성을 주면서 감염의 확산을 최소화할 수 있으리라 기대한다.

Keywords

References

  1. Korea Disease Control and Prevention Agency. COVID-19 response guidelines (for local government) Edition 13-1, Aug 15 2022 [Internet]. Cheongju: Korea Disease Control and Prevention Agency; 2022 [cited 2022 Sep 14]. Available from: http://ncov.mohw.go.kr/upload/viewer/skin/doc.html?fn=1660304334151_20220812203856.pdf&rs=/upload/viewer/result/202209/. 
  2. Kim KH, Cho EY, Kim DH, Kim HW, Park JY, Eun BW, et al. Guidelines for coronavirus disease 2019 response in children and adolescents. Pediatr Infect Vaccine 2020;27:24-34.  https://doi.org/10.14776/piv.2020.27.e11
  3. The Korean Society of Pediatric Infectious Diseases. COVID-19 response guidelines (neonate, infant, children), Dec 31 2020 [Internet]. Seoul: The Korean Society of Pediatric Infectious Diseases; 2020 [cited 2022 Sep 14]. Available from: https://www.kspid.or.kr/board/list.html?num=587&cate=&start=20&sort=top2%20desc,%20top%20desc,%20num%20desc&code=notice&key=&keyword=. 
  4. American Academy of Pediatrics. Management of infants born to mothers with suspected or confirmed COVID-19 [Internet]. Washington, D.C.: American Academy of Pediatrics; 2022 [cited 2022 Sep 20]. Available from: https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/clinicalguidance/faqs-management-of-infants-born-to-covid-19-mothers/. 
  5. Korean Society of Pediatric Infectious Diseases. Guideline for isolation and test of neonate born in mother with COVID-19 [Internet]. Seoul: Korean Society of Pediatric Infectious Diseases; 2022 [cited 2022 Sep 28]. Available from: https://www.kspid.or.kr/board/list.html?code=notice&num=780&cate=%B0%F8%C1%F6%A1%A4%BC%D2%BD%C4&. 
  6. Vigil-Vazquez S, Carrasco-Garcia I, Hernanz-Lobo A, Manzanares A, Perez-Perez A, Toledano-Revenga J, et al. Impact of gestational COVID-19 on neonatal outcomes: is vertical infection possible? Pediatr Infect Dis J 2022;41:466-72.  https://doi.org/10.1097/INF.0000000000003518
  7. Mullins E, Perry A, Banerjee J, Townson J, Grozeva D, Milton R, et al. Pregnancy and neonatal outcomes of COVID-19: the PAN-COVID study. Eur J Obstet Gynecol Reprod Biol 2022;276:161-7.  https://doi.org/10.1016/j.ejogrb.2022.07.010
  8. Centers for Disease Control and Prevention. Data on COVID-19 during pregnancy: birth and infant outcomes [Internet]. Atlanta: Centers for Disease Control and Prevention; 2022 [cited 2022 Sep 14]. Available from: https://covid.cdc.gov/covid-data-tracker/#pregnant-birth-infant. 
  9. New South Wales Government. Re-admission of babies of women with suspected or confirmed COVID-19 [Internet]. Sydney: NSW Government; 2022 [cited 2022 Sep 26]. Available from: https://www.health.nsw.gov.au/Infectious/covid-19/communities-of-practice/Pages/guide-neonatal-services.aspx. 
  10. British Association of Perinatal Medicine. COVID-19 pandemic frequently asked questions within neonatal services [Internet]. London: British Association of Perinatal Medicine; 2022 [cited 2022 Sep 26]. Available from: https://www.bapm.org/pages/182-perinatal-covid-19-resources.