Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Cohort Profile: Korean Tuberculosis and Post-Tuberculosis Cohort Constructed by Linking the Korean National Tuberculosis Surveillance System and National Health Information Database

  • Jeong, Dawoon (The Korean Institute of Tuberculosis, Korean National Tuberculosis Association) ;
  • Kang, Hee-Yeon (Department of Health Policy and Management, Seoul National University College of Medicine) ;
  • Kim, Jinsun (Division of Tuberculosis Prevention and Control, Bureau of Infectious Disease Policy, Korea Disease Control and Prevention Agency) ;
  • Lee, Hyewon (Division of Tuberculosis Prevention and Control, Bureau of Infectious Disease Policy, Korea Disease Control and Prevention Agency) ;
  • Yoo, Bit-Na (National Evidence-based Collaborating Agency) ;
  • Kim, Hee-Sun (National Evidence-based Collaborating Agency) ;
  • Choi, Hongjo (Department of Preventive Medicine, Konyang University College of Medicine)
  • Received : 2021.12.15
  • Accepted : 2022.03.29
  • Published : 2022.05.31
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Abstract

We aimed to review the current data composition of the Korean Tuberculosis and Post-Tuberculosis Cohort, which was constructed by linking the Korean Tuberculosis Surveillance System (KNTSS; established and operated by the Korean Disease Control and Prevention Agency since 2000) and the National Health Information Database (NHID; established by the National Health Insurance Service in 2012). The following data were linked: KNTSS data pertaining to patients diagnosed with tuberculosis between 2011 and 2018, NHID data of patients with a history of tuberculosis and related diseases between 2006 and 2018, and data (obtained from the Statistics Korea database) on causes of death. Data from 300 117 tuberculosis patients (177 206 men and 122 911 women) were linked. The rate of treatment success for new cases was highest in 2015 (86.7%), with a gradual decrease thereafter. The treatment success rate for previously treated cases showed an increasing trend until 2014 (79.0%) and decreased thereafter. In total, 53 906 deaths were confirmed among tuberculosis patients included in the cohort. The Korean Tuberculosis and Post-Tuberculosis Cohort can be used to analyze different measurement variables in an integrated manner depending on the data source. Therefore, these cohort data can be used in future epidemiological studies and research on policy-effect analysis, treatment outcome analysis, and health-related behaviors such as treatment discontinuation.

Keywords

Acknowledgement

This study used the National Health Information Database (NHIS-2019-1-662) of the National Health Insurance Service (NHIS).

References

  1. World Health Organization. Global tuberculosis report 2020 [cited 2021 Nov 25]. Available from: https://www.who.int/publications/i/item/9789240013131.
  2. Cho KS. Tuberculosis control in the Republic of Korea. Epidemiol Health 2018;40:e2018036. https://doi.org/10.4178/epih.e2018036
  3. Go U, Park M, Kim UN, Lee S, Han S, Lee J, et al. Tuberculosis prevention and care in Korea: evolution of policy and practice. J Clin Tuberc Other Mycobact Dis 2018;11:28-36. https://doi.org/10.1016/j.jctube.2018.04.006
  4. Na BJ, Kang MY, Hong JY, Kim EY, Kim KY, Lee MS, et al. The ratio of medical aid over health insurance of age adjusted mortality rate of tuberculosis and related factors. J Agric Med Community Health 2006;31(1):9-20 (Korean).
  5. Kim HJ. Current status of tuberculosis in Korea. Korean J Med 2012;82(3):257-262 (Korean). https://doi.org/10.3904/kjm.2012.82.3.257
  6. Kang HY, Yoo H, Park W, Go U, Jeong E, Jung KS, et al. Tuberculosis notification completeness and timeliness in the Republic of Korea during 2012-2014. Osong Public Health Res Perspect 2016;7(5):320-326. https://doi.org/10.1016/j.phrp.2016.08.002
  7. Seong SC, Kim YY, Khang YH, Heon Park J, Kang HJ, Lee H, et al. Data resource profile: the national health information data-base of the National Health Insurance Service in South Korea. Int J Epidemiol 2017;46(3):799-800. https://doi.org/10.1093/ije/dyw253
  8. Chu H, Shih CJ, Lee YJ, Kuo SC, Hsu YT, Ou SM, et al. Risk of tuberculosis among healthcare workers in an intermediate-burden country: a nationwide population study. J Infect 2014;69(6):525-532. https://doi.org/10.1016/j.jinf.2014.06.019
  9. Lee CC, Lee MG, Hsu WT, Park JY, Porta L, Liu MA, et al. Use of calcium channel blockers and risk of active tuberculosis disease: a population-based analysis. Hypertension 2021;77(2):328-337. https://doi.org/10.1161/HYPERTENSIONAHA.120.15534
  10. Chen YT, Kuo SC, Chao PW, Chang YY. Use of lipid-lowering agents is not associated with improved outcomes for tuberculosis patients on standard-course therapy: a populationbased cohort study. PLoS One 2019;14(1):e0210479. https://doi.org/10.1371/journal.pone.0210479
  11. Lalor MK, Mohiyuddin T, Uddin T, Thomas HL, Lipman M, Campbell CN. The challenge of estimating tuberculosis mortality accurately in England and Wales. Int J Tuberc Lung Dis 2018;22(5):572-578. https://doi.org/10.5588/ijtld.17.0695
  12. Yu S, Sohn H, Kim HY, Kim H, Oh KH, Kim HJ, et al. Evaluating the impact of the nationwide public-private mix (PPM) program for tuberculosis under National Health Insurance in South Korea: a difference in differences analysis. PLoS Med 2021;18(7):e1003717. https://doi.org/10.1371/journal.pmed.1003717
  13. World Health Organization. International statistical classification of diseases and related health problems 10th revision [cited 2021 Nov 25]. Available from: https://icd.who.int/browse10/2019/en.
  14. Korea Informative Classification of Disease. Korean standard classification of diseases and causes of death (KCD-7) [cited 2021 Nov 25]. Available from: https://www.koicd.kr/kcd/kcds.do (Korean).
  15. Shin HY, Lee JY, Kim JE, Lee S, Youn H, Kim H, et al. Cause-of-death statistics in 2016 in the Republic of Korea. J Korean Med Assoc 2018;61(9):573-584 (Korean). https://doi.org/10.5124/jkma.2018.61.9.573
  16. Korean Statistical Information Services. Deaths by cause (103 item); 2021 [cited 2021 Nov 25]. Available from: https://kosis.kr/statHtml/statHtml.do?orgId=101&tblId=DT_1B34E02&conn_path=I2&language=en.